BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 10660119)

  • 1. Role of cytochrome P450 and glutathione S-transferase alpha in the metabolism and cytotoxicity of trichloroethylene in rat kidney.
    Cummings BS; Parker JC; Lash LH
    Biochem Pharmacol; 2000 Mar; 59(5):531-43. PubMed ID: 10660119
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glutathione conjugation of trichloroethylene in rats and mice: sex-, species-, and tissue-dependent differences.
    Lash LH; Qian W; Putt DA; Jacobs K; Elfarra AA; Krause RJ; Parker JC
    Drug Metab Dispos; 1998 Jan; 26(1):12-9. PubMed ID: 9443846
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutathione conjugation of trichloroethylene in human liver and kidney: kinetics and individual variation.
    Lash LH; Lipscomb JC; Putt DA; Parker JC
    Drug Metab Dispos; 1999 Mar; 27(3):351-9. PubMed ID: 10064565
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytotoxicity of trichloroethylene and S-(1, 2-dichlorovinyl)-L-cysteine in primary cultures of rat renal proximal tubular and distal tubular cells.
    Cummings BS; Zangar RC; Novak RF; Lash LH
    Toxicology; 2000 Sep; 150(1-3):83-98. PubMed ID: 10996665
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-L-cysteine in freshly isolated human proximal tubular cells.
    Cummings BS; Lash LH
    Toxicol Sci; 2000 Feb; 53(2):458-66. PubMed ID: 10696794
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glutathione-dependent metabolism of trichloroethylene in isolated liver and kidney cells of rats and its role in mitochondrial and cellular toxicity.
    Lash LH; Xu Y; Elfarra AA; Duescher RJ; Parker JC
    Drug Metab Dispos; 1995 Aug; 23(8):846-53. PubMed ID: 7493552
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interactive toxicity of inorganic mercury and trichloroethylene in rat and human proximal tubules: effects on apoptosis, necrosis, and glutathione status.
    Lash LH; Putt DA; Hueni SE; Payton SG; Zwickl J
    Toxicol Appl Pharmacol; 2007 Jun; 221(3):349-62. PubMed ID: 17481684
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytochrome p450-dependent metabolism of trichloroethylene in rat kidney.
    Cummings BS; Parker JC; Lash LH
    Toxicol Sci; 2001 Mar; 60(1):11-9. PubMed ID: 11222868
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione.
    Lash LH; Putt DA; Huang P; Hueni SE; Parker JC
    Toxicology; 2007 Jun; 235(1-2):11-26. PubMed ID: 17433522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk assessment.
    Capinha L; Jennings P; Commandeur JNM
    Toxicol Lett; 2021 May; 341():94-106. PubMed ID: 33539969
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of S-(1,2-dichlorovinyl)glutathione in the blood of human volunteers exposed to trichloroethylene.
    Lash LH; Putt DA; Brashear WT; Abbas R; Parker JC; Fisher JW
    J Toxicol Environ Health A; 1999 Jan; 56(1):1-21. PubMed ID: 9923751
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analytical methods impact estimates of trichloroethylene's glutathione conjugation and risk assessment.
    Zhang F; Marty S; Budinsky R; Bartels M; Pottenger LH; Bus J; Bevan C; Erskine T; Clark A; Holzheuer B; Markham D
    Toxicol Lett; 2018 Oct; 296():82-94. PubMed ID: 30081224
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Renal cellular transport of exogenous glutathione: heterogeneity at physiological and pharmacological concentrations.
    Lash LH; Putt DA
    Biochem Pharmacol; 1999 Sep; 58(5):897-907. PubMed ID: 10449202
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro methods of assessing renal damage.
    Lash LH
    Toxicol Pathol; 1998; 26(1):33-42. PubMed ID: 9502385
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Renal cell type specificity of cephalosporin-induced cytotoxicity in suspensions of isolated proximal tubular and distal tubular cells.
    Lash LH; Tokarz JJ; Woods EB
    Toxicology; 1994; 94(1-3):97-118. PubMed ID: 7801333
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cellular distribution of cytochromes P-450 in the rat kidney.
    Cummings BS; Zangar RC; Novak RF; Lash LH
    Drug Metab Dispos; 1999 Apr; 27(4):542-8. PubMed ID: 10101150
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation.
    Bernauer U; Birner G; Dekant W; Henschler D
    Arch Toxicol; 1996; 70(6):338-46. PubMed ID: 8975632
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular and subcellular heterogeneity of glutathione metabolism and transport in rat kidney cells.
    Lash LH; Visarius TM; Sall JM; Qian W; Tokarz JJ
    Toxicology; 1998 Sep; 130(1):1-15. PubMed ID: 9846992
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Renal and hepatic toxicity of trichloroethylene and its glutathione-derived metabolites in rats and mice: sex-, species-, and tissue-dependent differences.
    Lash LH; Qian W; Putt DA; Hueni SE; Elfarra AA; Krause RJ; Parker JC
    J Pharmacol Exp Ther; 2001 Apr; 297(1):155-64. PubMed ID: 11259540
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oxidative stress and cytotoxicity of 4-(2-thienyl)butyric acid in isolated rat renal proximal tubular and distal tubular cells.
    Lash LH; Tokarz JJ
    Toxicology; 1995 Dec; 103(3):167-75. PubMed ID: 8553360
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.