303 related articles for article (PubMed ID: 10662693)
21. Chain initiation on the soraphen-producing modular polyketide synthase from Sorangium cellulosum.
Wilkinson CJ; Frost EJ; Staunton J; Leadlay PF
Chem Biol; 2001 Dec; 8(12):1197-208. PubMed ID: 11755398
[TBL] [Abstract][Full Text] [Related]
22. Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase.
Rowe CJ; Böhm IU; Thomas IP; Wilkinson B; Rudd BA; Foster G; Blackaby AP; Sidebottom PJ; Roddis Y; Buss AD; Staunton J; Leadlay PF
Chem Biol; 2001 May; 8(5):475-85. PubMed ID: 11358694
[TBL] [Abstract][Full Text] [Related]
23. The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase.
Beck BJ; Yoon YJ; Reynolds KA; Sherman DH
Chem Biol; 2002 May; 9(5):575-83. PubMed ID: 12031664
[TBL] [Abstract][Full Text] [Related]
24. Rapid engineering of polyketide overproduction by gene transfer to industrially optimized strains.
Rodriguez E; Hu Z; Ou S; Volchegursky Y; Hutchinson CR; McDaniel R
J Ind Microbiol Biotechnol; 2003 Aug; 30(8):480-8. PubMed ID: 12698320
[TBL] [Abstract][Full Text] [Related]
25. Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase.
Kao CM; Pieper R; Cane DE; Khosla C
Biochemistry; 1996 Sep; 35(38):12363-8. PubMed ID: 8823171
[TBL] [Abstract][Full Text] [Related]
26. Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae.
Jung WS; Lee SK; Hong JS; Park SR; Jeong SJ; Han AR; Sohng JK; Kim BG; Choi CY; Sherman DH; Yoon YJ
Appl Microbiol Biotechnol; 2006 Oct; 72(4):763-9. PubMed ID: 16493552
[TBL] [Abstract][Full Text] [Related]
27. Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units.
Lau J; Fu H; Cane DE; Khosla C
Biochemistry; 1999 Feb; 38(5):1643-51. PubMed ID: 9931032
[TBL] [Abstract][Full Text] [Related]
28. Complex organization of the Streptomyces avermitilis genes encoding the avermectin polyketide synthase.
MacNeil DJ; Occi JL; Gewain KM; MacNeil T; Gibbons PH; Ruby CL; Danis SJ
Gene; 1992 Jun; 115(1-2):119-25. PubMed ID: 1612425
[TBL] [Abstract][Full Text] [Related]
29. Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives.
Ruan X; Pereda A; Stassi DL; Zeidner D; Summers RG; Jackson M; Shivakumar A; Kakavas S; Staver MJ; Donadio S; Katz L
J Bacteriol; 1997 Oct; 179(20):6416-25. PubMed ID: 9335291
[TBL] [Abstract][Full Text] [Related]
30. A host-vector system for analysis and manipulation of rifamycin polyketide biosynthesis in Amycolatopsis mediterranei.
Hu Z; Hunziker D; Hutchinson CR; Khosla C
Microbiology (Reading); 1999 Sep; 145 ( Pt 9)():2335-2341. PubMed ID: 10517586
[TBL] [Abstract][Full Text] [Related]
31. Heterologous expression in Escherichia coli of an intact multienzyme component of the erythromycin-producing polyketide synthase.
Roberts GA; Staunton J; Leadlay PF
Eur J Biochem; 1993 May; 214(1):305-11. PubMed ID: 8508800
[TBL] [Abstract][Full Text] [Related]
32. Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases.
Pieper R; Luo G; Cane DE; Khosla C
Nature; 1995 Nov; 378(6554):263-6. PubMed ID: 7477343
[TBL] [Abstract][Full Text] [Related]
33. Functional dissection of a multimodular polypeptide of the pikromycin polyketide synthase into monomodules by using a matched pair of heterologous docking domains.
Yan J; Gupta S; Sherman DH; Reynolds KA
Chembiochem; 2009 Jun; 10(9):1537-43. PubMed ID: 19437523
[TBL] [Abstract][Full Text] [Related]
34. The leptomycin gene cluster and its heterologous expression in Streptomyces lividans.
Hu Z; Reid R; Gramajo H
J Antibiot (Tokyo); 2005 Oct; 58(10):625-33. PubMed ID: 16392678
[TBL] [Abstract][Full Text] [Related]
35. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei.
Tang L; Yoon YJ; Choi CY; Hutchinson CR
Gene; 1998 Aug; 216(2):255-65. PubMed ID: 9729415
[TBL] [Abstract][Full Text] [Related]
36. Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues.
Ranganathan A; Timoney M; Bycroft M; Cortés J; Thomas IP; Wilkinson B; Kellenberger L; Hanefeld U; Galloway IS; Staunton J; Leadlay PF
Chem Biol; 1999 Oct; 6(10):731-41. PubMed ID: 10508677
[TBL] [Abstract][Full Text] [Related]
37. Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.
McDaniel R; Thamchaipenet A; Gustafsson C; Fu H; Betlach M; Ashley G
Proc Natl Acad Sci U S A; 1999 Mar; 96(5):1846-51. PubMed ID: 10051557
[TBL] [Abstract][Full Text] [Related]
38. Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules.
Hans M; Hornung A; Dziarnowski A; Cane DE; Khosla C
J Am Chem Soc; 2003 May; 125(18):5366-74. PubMed ID: 12720450
[TBL] [Abstract][Full Text] [Related]
39. Iterative type II polyketide synthases, cyclases and ketoreductases exhibit context-dependent behavior in the biosynthesis of linear and angular decapolyketides.
Meurer G; Gerlitz M; Wendt-Pienkowski E; Vining LC; Rohr J; Hutchinson CR
Chem Biol; 1997 Jun; 4(6):433-43. PubMed ID: 9224566
[TBL] [Abstract][Full Text] [Related]
40. Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases.
Tsai SC; Lu H; Cane DE; Khosla C; Stroud RM
Biochemistry; 2002 Oct; 41(42):12598-606. PubMed ID: 12379102
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
