BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 10663384)

  • 1. CYP2A6 genetic polymorphisms and liver microsomal coumarin and nicotine oxidation activities in Japanese and Caucasians.
    Inoue K; Yamazaki H; Shimada T
    Arch Toxicol; 2000 Jan; 73(10-11):532-9. PubMed ID: 10663384
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ethnic-related differences in coumarin 7-hydroxylation activities catalyzed by cytochrome P4502A6 in liver microsomes of Japanese and Caucasian populations.
    Shimada T; Yamazaki H; Guengerich FP
    Xenobiotica; 1996 Apr; 26(4):395-403. PubMed ID: 9173680
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502).
    Nunoya K; Yokoi T; Kimura K; Inoue K; Kodama T; Funayama M; Nagashima K; Funae Y; Green C; Kinoshita M; Kamataki T
    Pharmacogenetics; 1998 Jun; 8(3):239-49. PubMed ID: 9682269
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparison of cytochrome P450 2A6 polymorphism frequencies in Caucasians and African-Americans using a new one-step PCR-RFLP genotyping method.
    Paschke T; Riefler M; Schuler-Metz A; Wolz L; Scherer G; McBride CM; Bepler G
    Toxicology; 2001 Nov; 168(3):259-68. PubMed ID: 11684323
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel polymorphism of human CYP2A6 gene CYP2A6*17 has an amino acid substitution (V365M) that decreases enzymatic activity in vitro and in vivo.
    Fukami T; Nakajima M; Yoshida R; Tsuchiya Y; Fujiki Y; Katoh M; McLeod HL; Yokoi T
    Clin Pharmacol Ther; 2004 Dec; 76(6):519-27. PubMed ID: 15592323
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations.
    Inoue K; Yamazaki H; Imiya K; Akasaka S; Guengerich FP; Shimada T
    Pharmacogenetics; 1997 Apr; 7(2):103-13. PubMed ID: 9170147
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Determination of coumarin metabolism in Turkish population.
    Cok I; Aygün Kocabaş N; Cholerton S; Karakaya AE; Sardaş S
    Hum Exp Toxicol; 2001 Apr; 20(4):179-84. PubMed ID: 11393269
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel single nucleotide polymorphism altering stability and activity of CYP2a6.
    Ariyoshi N; Sawamura Y; Kamataki T
    Biochem Biophys Res Commun; 2001 Mar; 281(3):810-4. PubMed ID: 11237731
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of novel CYP2A6 polymorphic alleles (CYP2A6*18 and CYP2A6*19) that affect enzymatic activity.
    Fukami T; Nakajima M; Higashi E; Yamanaka H; Sakai H; McLeod HL; Yokoi T
    Drug Metab Dispos; 2005 Aug; 33(8):1202-10. PubMed ID: 15900015
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Low frequency of CYP2A6 gene polymorphism as revealed by a one-step polymerase chain reaction method.
    Chen GF; Tang YM; Green B; Lin DX; Guengerich FP; Daly AK; Caporaso NE; Kadlubar FF
    Pharmacogenetics; 1999 Jun; 9(3):327-32. PubMed ID: 10471064
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Three haplotypes associated with CYP2A6 phenotypes in Caucasians.
    Haberl M; Anwald B; Klein K; Weil R; Fuss C; Gepdiremen A; Zanger UM; Meyer UA; Wojnowski L
    Pharmacogenet Genomics; 2005 Sep; 15(9):609-24. PubMed ID: 16041240
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of coumarin 7-hydroxylase activity in human liver microsomes.
    Draper AJ; Madan A; Parkinson A
    Arch Biochem Biophys; 1997 May; 341(1):47-61. PubMed ID: 9143352
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Porcine CYP2A polymorphisms and activity.
    Skaanild MT; Friis C
    Basic Clin Pharmacol Toxicol; 2005 Aug; 97(2):115-21. PubMed ID: 15998359
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nicotine metabolism and CYP2A6 allele frequencies in Koreans.
    Kwon JT; Nakajima M; Chai S; Yom YK; Kim HK; Yamazaki H; Sohn DR; Yamamoto T; Kuroiwa Y; Yokoi T
    Pharmacogenetics; 2001 Jun; 11(4):317-23. PubMed ID: 11434509
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of a genotype previously designated as CYP2A6 D-type: CYP2A6*4B, another entire gene deletion allele of the CYP2A6 gene in Japanese.
    Ariyoshi N; Sekine H; Saito K; Kamataki T
    Pharmacogenetics; 2002 Aug; 12(6):501-4. PubMed ID: 12172220
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of human cytochrome P4502A6 in C-oxidation of nicotine.
    Nakajima M; Yamamoto T; Nunoya K; Yokoi T; Nagashima K; Inoue K; Funae Y; Shimada N; Kamataki T; Kuroiwa Y
    Drug Metab Dispos; 1996 Nov; 24(11):1212-7. PubMed ID: 8937855
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The significance of the homozygous CYP2A6 deletion on nicotine metabolism: a new genotyping method of CYP2A6 using a single PCR-RFLP.
    Kitagawa K; Kunugita N; Katoh T; Yang M; Kawamoto T
    Biochem Biophys Res Commun; 1999 Aug; 262(1):146-51. PubMed ID: 10448083
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation.
    Pearce R; Greenway D; Parkinson A
    Arch Biochem Biophys; 1992 Oct; 298(1):211-25. PubMed ID: 1381906
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin.
    Hadidi H; Zahlsen K; Idle JR; Cholerton S
    Food Chem Toxicol; 1997 Sep; 35(9):903-7. PubMed ID: 9409631
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of association between smoking and CYP2A6 gene polymorphisms in A Japanese population.
    Zhang X; Amemo K; Ameno S; Iwahashi K; Kinoshita H; Kubota T; Mostofa J; Ijiri I
    Nihon Arukoru Yakubutsu Igakkai Zasshi; 2001 Oct; 36(5):486-90. PubMed ID: 11725533
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.