BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

82 related articles for article (PubMed ID: 10666019)

  • 1. Focus on "Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of DeltaF508-CFTR".
    Bradbury NA
    Am J Physiol Cell Physiol; 2000 Feb; 278(2):C257-8. PubMed ID: 10666019
    [No Abstract]   [Full Text] [Related]  

  • 2. Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of DeltaF508-CFTR.
    Rubenstein RC; Zeitlin PL
    Am J Physiol Cell Physiol; 2000 Feb; 278(2):C259-67. PubMed ID: 10666020
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of HSP70 promotes DeltaF508 CFTR trafficking.
    Choo-Kang LR; Zeitlin PL
    Am J Physiol Lung Cell Mol Physiol; 2001 Jul; 281(1):L58-68. PubMed ID: 11404246
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sodium 4-phenylbutyrate downregulates HSC70 expression by facilitating mRNA degradation.
    Rubenstein RC; Lyons BM
    Am J Physiol Lung Cell Mol Physiol; 2001 Jul; 281(1):L43-51. PubMed ID: 11404244
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of deltaF508 cystic fibrosis transmembrane regulator trafficking and function with 4-phenylbutyrate and flavonoids.
    Lim M; McKenzie K; Floyd AD; Kwon E; Zeitlin PL
    Am J Respir Cell Mol Biol; 2004 Sep; 31(3):351-7. PubMed ID: 15191910
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis.
    Meacham GC; Lu Z; King S; Sorscher E; Tousson A; Cyr DM
    EMBO J; 1999 Mar; 18(6):1492-505. PubMed ID: 10075921
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulation of epithelial sodium channel trafficking and function by sodium 4-phenylbutyrate in human nasal epithelial cells.
    Prulière-Escabasse V; Planès C; Escudier E; Fanen P; Coste A; Clerici C
    J Biol Chem; 2007 Nov; 282(47):34048-57. PubMed ID: 17890229
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The CFTR-Associated Ligand Arrests the Trafficking of the Mutant ΔF508 CFTR Channel in the ER Contributing to Cystic Fibrosis.
    Bergbower E; Boinot C; Sabirzhanova I; Guggino W; Cebotaru L
    Cell Physiol Biochem; 2018; 45(2):639-655. PubMed ID: 29402832
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A small molecule that binds to an ATPase domain of Hsc70 promotes membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator.
    Cho HJ; Gee HY; Baek KH; Ko SK; Park JM; Lee H; Kim ND; Lee MG; Shin I
    J Am Chem Soc; 2011 Dec; 133(50):20267-76. PubMed ID: 22074182
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of deltaF508 CFTR in a cystic fibrosis respiratory epithelial cell line by 4-phenylbutyrate, genistein and CPX.
    Andersson C; Roomans GM
    Eur Respir J; 2000 May; 15(5):937-41. PubMed ID: 10853862
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70.
    Farinha CM; Nogueira P; Mendes F; Penque D; Amaral MD
    Biochem J; 2002 Sep; 366(Pt 3):797-806. PubMed ID: 12069690
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proinflammatory effect of sodium 4-phenylbutyrate in deltaF508-cystic fibrosis transmembrane conductance regulator lung epithelial cells: involvement of extracellular signal-regulated protein kinase 1/2 and c-Jun-NH2-terminal kinase signaling.
    Roque T; Boncoeur E; Saint-Criq V; Bonvin E; Clement A; Tabary O; Jacquot J
    J Pharmacol Exp Ther; 2008 Sep; 326(3):949-56. PubMed ID: 18574003
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The molecular chaperone Hsc70 assists the in vitro folding of the N-terminal nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator.
    Strickland E; Qu BH; Millen L; Thomas PJ
    J Biol Chem; 1997 Oct; 272(41):25421-4. PubMed ID: 9325249
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator.
    Alberti S; Böhse K; Arndt V; Schmitz A; Höhfeld J
    Mol Biol Cell; 2004 Sep; 15(9):4003-10. PubMed ID: 15215316
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hsp70 and DNAJA2 limit CFTR levels through degradation.
    Kim Chiaw P; Hantouche C; Wong MJH; Matthes E; Robert R; Hanrahan JW; Shrier A; Young JC
    PLoS One; 2019; 14(8):e0220984. PubMed ID: 31408507
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 4-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cells.
    Suaud L; Miller K; Panichelli AE; Randell RL; Marando CM; Rubenstein RC
    J Biol Chem; 2011 Dec; 286(52):45083-92. PubMed ID: 22069317
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.
    Rubenstein RC; Egan ME; Zeitlin PL
    J Clin Invest; 1997 Nov; 100(10):2457-65. PubMed ID: 9366560
    [TBL] [Abstract][Full Text] [Related]  

  • 18. S-nitrosylating agents: a novel class of compounds that increase cystic fibrosis transmembrane conductance regulator expression and maturation in epithelial cells.
    Zaman K; Carraro S; Doherty J; Henderson EM; Lendermon E; Liu L; Verghese G; Zigler M; Ross M; Park E; Palmer LA; Doctor A; Stamler JS; Gaston B
    Mol Pharmacol; 2006 Oct; 70(4):1435-42. PubMed ID: 16857740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperone.
    Scott-Ward TS; Amaral MD
    FEBS J; 2009 Dec; 276(23):7097-109. PubMed ID: 19878303
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence of CFTR function in cystic fibrosis after systemic administration of 4-phenylbutyrate.
    Zeitlin PL; Diener-West M; Rubenstein RC; Boyle MP; Lee CK; Brass-Ernst L
    Mol Ther; 2002 Jul; 6(1):119-26. PubMed ID: 12095312
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.