BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

617 related articles for article (PubMed ID: 10667586)

  • 1. The geldanamycins are potent inhibitors of the hepatocyte growth factor/scatter factor-met-urokinase plasminogen activator-plasmin proteolytic network.
    Webb CP; Hose CD; Koochekpour S; Jeffers M; Oskarsson M; Sausville E; Monks A; Vande Woude GF
    Cancer Res; 2000 Jan; 60(2):342-9. PubMed ID: 10667586
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Geldanamycins exquisitely inhibit HGF/SF-mediated tumor cell invasion.
    Xie Q; Gao CF; Shinomiya N; Sausville E; Hay R; Gustafson M; Shen Y; Wenkert D; Vande Woude GF
    Oncogene; 2005 May; 24(23):3697-707. PubMed ID: 15782129
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.
    Bauer TW; Liu W; Fan F; Camp ER; Yang A; Somcio RJ; Bucana CD; Callahan J; Parry GC; Evans DB; Boyd DD; Mazar AP; Ellis LM
    Cancer Res; 2005 Sep; 65(17):7775-81. PubMed ID: 16140945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of the plasminogen activator and matrix metalloproteinase systems in epidermal growth factor- and scatter factor-stimulated invasion of carcinoma cells.
    Rosenthal EL; Johnson TM; Allen ED; Apel IJ; Punturieri A; Weiss SJ
    Cancer Res; 1998 Nov; 58(22):5221-30. PubMed ID: 9823336
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.
    Besser D; Bardelli A; Didichenko S; Thelen M; Comoglio PM; Ponzetto C; Nagamine Y
    Oncogene; 1997 Feb; 14(6):705-11. PubMed ID: 9038378
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hepatocyte growth factor/scatter factor promotes retinal angiogenesis through increased urokinase expression.
    Colombo ES; Menicucci G; McGuire PG; Das A
    Invest Ophthalmol Vis Sci; 2007 Apr; 48(4):1793-800. PubMed ID: 17389513
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Autocrine hepatocyte growth factor/scatter factor-Met signaling induces transformation and the invasive/metastastic phenotype in C127 cells.
    Jeffers M; Rong S; Anver M; Vande Woude GF
    Oncogene; 1996 Aug; 13(4):853-6. PubMed ID: 8761307
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.
    Maulik G; Kijima T; Ma PC; Ghosh SK; Lin J; Shapiro GI; Schaefer E; Tibaldi E; Johnson BE; Salgia R
    Clin Cancer Res; 2002 Feb; 8(2):620-7. PubMed ID: 11839685
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel recombinant soluble splice variant of Met is a potent antagonist of the hepatocyte growth factor/scatter factor-Met pathway.
    Tiran Z; Oren A; Hermesh C; Rotman G; Levine Z; Amitai H; Handelsman T; Beiman M; Chen A; Landesman-Milo D; Dassa L; Peres Y; Koifman C; Glezer S; Vidal-Finkelstein R; Bahat K; Pergam T; Israel C; Horev J; Tsarfaty I; Ayalon-Soffer M
    Clin Cancer Res; 2008 Jul; 14(14):4612-21. PubMed ID: 18628476
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system.
    Lee DH; Yang Y; Lee SJ; Kim KY; Koo TH; Shin SM; Song KS; Lee YH; Kim YJ; Lee JJ; Choi I; Lee JH
    Cancer Res; 2003 Aug; 63(15):4648-55. PubMed ID: 12907645
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis.
    Zhang YW; Wang LM; Jove R; Vande Woude GF
    Oncogene; 2002 Jan; 21(2):217-26. PubMed ID: 11803465
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy.
    Li Y; Lal B; Kwon S; Fan X; Saldanha U; Reznik TE; Kuchner EB; Eberhart C; Laterra J; Abounader R
    Cancer Res; 2005 Oct; 65(20):9355-62. PubMed ID: 16230398
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of HGF/SF-Met signaling in prostate adenocarcinoma cells: evidence for alternative mechanisms leading to a metastatic phenotype in Pr-14c.
    MacDougall CA; Vargas M; Soares CR; Holzer RG; Ide AE; Jorcyk CL
    Prostate; 2005 Jul; 64(2):139-48. PubMed ID: 15678502
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of urokinase plasminogen activator receptor in thrombospondin 1-mediated tumor cell invasion.
    Albo D; Berger DH; Rothman VL; Tuszynski GP
    J Surg Res; 1999 Apr; 82(2):331-8. PubMed ID: 10090848
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interaction between cancer cells and stromal fibroblasts is required for activation of the uPAR-uPA-MMP-2 cascade in pancreatic cancer metastasis.
    He Y; Liu XD; Chen ZY; Zhu J; Xiong Y; Li K; Dong JH; Li X
    Clin Cancer Res; 2007 Jun; 13(11):3115-24. PubMed ID: 17545513
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HGF/SF and its receptor c-MET play a minor role in the dissemination of human B-lymphoma cells in SCID mice.
    Weimar IS; Weijer K; van den Berk PC; Muller EJ; Miranda N; Bakker AQ; Heemskerk MH; Hekman A; de Gast GC; Gerritsen WR
    Br J Cancer; 1999 Sep; 81(1):43-53. PubMed ID: 10487611
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of retarded liver regeneration in plasminogen activator-deficient mice: impaired activation of hepatocyte growth factor after Fas-mediated massive hepatic apoptosis.
    Shimizu M; Hara A; Okuno M; Matsuno H; Okada K; Ueshima S; Matsuo O; Niwa M; Akita K; Yamada Y; Yoshimi N; Uematsu T; Kojima S; Friedman SL; Moriwaki H; Mori H
    Hepatology; 2001 Mar; 33(3):569-76. PubMed ID: 11230736
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular characteristics of HGF-SF and its role in cell motility and invasion.
    Weidner KM; Hartmann G; Naldini L; Comoglio PM; Sachs M; Fonatsch C; Rieder H; Birchmeier W
    EXS; 1993; 65():311-28. PubMed ID: 8380739
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Scatter factor stimulates tumor growth and tumor angiogenesis in human breast cancers in the mammary fat pads of nude mice.
    Lamszus K; Jin L; Fuchs A; Shi E; Chowdhury S; Yao Y; Polverini PJ; Laterra J; Goldberg ID; Rosen EM
    Lab Invest; 1997 Mar; 76(3):339-53. PubMed ID: 9121117
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced invasion of hormone refractory prostate cancer cells through hepatocyte growth factor (HGF) induction of urokinase-type plasminogen activator (u-PA).
    Hall CL; Tsan R; Mugnai G; Mazar A; Radinsky R; Pettaway CA
    Prostate; 2004 May; 59(2):167-76. PubMed ID: 15042617
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.