222 related articles for article (PubMed ID: 10668854)
1. Deficient cotinine formation from nicotine is attributed to the whole deletion of the CYP2A6 gene in humans.
Nakajima M; Yamagishi S; Yamamoto H; Yamamoto T; Kuroiwa Y; Yokoi T
Clin Pharmacol Ther; 2000 Jan; 67(1):57-69. PubMed ID: 10668854
[TBL] [Abstract][Full Text] [Related]
2. Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans.
Nakajima M; Kwon JT; Tanaka N; Zenta T; Yamamoto Y; Yamamoto H; Yamazaki H; Yamamoto T; Kuroiwa Y; Yokoi T
Clin Pharmacol Ther; 2001 Jan; 69(1):72-8. PubMed ID: 11180041
[TBL] [Abstract][Full Text] [Related]
3. CYP2A6 genotype, phenotype, and the use of nicotine metabolites as biomarkers during ad libitum smoking.
Malaiyandi V; Goodz SD; Sellers EM; Tyndale RF
Cancer Epidemiol Biomarkers Prev; 2006 Oct; 15(10):1812-9. PubMed ID: 17035386
[TBL] [Abstract][Full Text] [Related]
4. Nicotine metabolism and CYP2A6 allele frequencies in Koreans.
Kwon JT; Nakajima M; Chai S; Yom YK; Kim HK; Yamazaki H; Sohn DR; Yamamoto T; Kuroiwa Y; Yokoi T
Pharmacogenetics; 2001 Jun; 11(4):317-23. PubMed ID: 11434509
[TBL] [Abstract][Full Text] [Related]
5. The significance of the homozygous CYP2A6 deletion on nicotine metabolism: a new genotyping method of CYP2A6 using a single PCR-RFLP.
Kitagawa K; Kunugita N; Katoh T; Yang M; Kawamoto T
Biochem Biophys Res Commun; 1999 Aug; 262(1):146-51. PubMed ID: 10448083
[TBL] [Abstract][Full Text] [Related]
6. Determinants of the rate of nicotine metabolism and effects on smoking behavior.
Johnstone E; Benowitz N; Cargill A; Jacob R; Hinks L; Day I; Murphy M; Walton R
Clin Pharmacol Ther; 2006 Oct; 80(4):319-30. PubMed ID: 17015050
[TBL] [Abstract][Full Text] [Related]
7. Effects of whole deletion of CYP2A6 on nicotine metabolism in humans.
Zhang X; Ameno K; Ameno S; Kinoshita H; Kubota T; Kumihashi M; Mostofa J; Iwahashi K; Ijiri I
Drug Chem Toxicol; 2002 May; 25(2):203-13. PubMed ID: 12024803
[TBL] [Abstract][Full Text] [Related]
8. Metabolic profile of nicotine in subjects whose CYP2A6 gene is deleted.
Yamanaka H; Nakajima M; Nishimura K; Yoshida R; Fukami T; Katoh M; Yokoi T
Eur J Pharm Sci; 2004 Aug; 22(5):419-25. PubMed ID: 15265511
[TBL] [Abstract][Full Text] [Related]
9. CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.
Benowitz NL; Swan GE; Jacob P; Lessov-Schlaggar CN; Tyndale RF
Clin Pharmacol Ther; 2006 Nov; 80(5):457-67. PubMed ID: 17112802
[TBL] [Abstract][Full Text] [Related]
10. A novel polymorphism of human CYP2A6 gene CYP2A6*17 has an amino acid substitution (V365M) that decreases enzymatic activity in vitro and in vivo.
Fukami T; Nakajima M; Yoshida R; Tsuchiya Y; Fujiki Y; Katoh M; McLeod HL; Yokoi T
Clin Pharmacol Ther; 2004 Dec; 76(6):519-27. PubMed ID: 15592323
[TBL] [Abstract][Full Text] [Related]
11. Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6.
Nakajima M; Kuroiwa Y; Yokoi T
Drug Metab Rev; 2002 Nov; 34(4):865-77. PubMed ID: 12487152
[TBL] [Abstract][Full Text] [Related]
12. Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity.
Dempsey D; Tutka P; Jacob P; Allen F; Schoedel K; Tyndale RF; Benowitz NL
Clin Pharmacol Ther; 2004 Jul; 76(1):64-72. PubMed ID: 15229465
[TBL] [Abstract][Full Text] [Related]
13. In vivo evaluation of coumarin and nicotine as probe drugs to predict the metabolic capacity of CYP2A6 due to genetic polymorphism in Thais.
Peamkrasatam S; Sriwatanakul K; Kiyotani K; Fujieda M; Yamazaki H; Kamataki T; Yoovathaworn K
Drug Metab Pharmacokinet; 2006 Dec; 21(6):475-84. PubMed ID: 17220563
[TBL] [Abstract][Full Text] [Related]
14. Duplications and defects in the CYP2A6 gene: identification, genotyping, and in vivo effects on smoking.
Rao Y; Hoffmann E; Zia M; Bodin L; Zeman M; Sellers EM; Tyndale RF
Mol Pharmacol; 2000 Oct; 58(4):747-55. PubMed ID: 10999944
[TBL] [Abstract][Full Text] [Related]
15. Variable CYP2A6-mediated nicotine metabolism alters smoking behavior and risk.
Tyndale RF; Sellers EM
Drug Metab Dispos; 2001 Apr; 29(4 Pt 2):548-52. PubMed ID: 11259349
[TBL] [Abstract][Full Text] [Related]
16. Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance.
Hukkanen J; Jacob P; Benowitz NL
Clin Pharmacol Ther; 2006 Nov; 80(5):522-30. PubMed ID: 17112808
[TBL] [Abstract][Full Text] [Related]
17. Comprehensive evaluation of variability in nicotine metabolism and CYP2A6 polymorphic alleles in four ethnic populations.
Nakajima M; Fukami T; Yamanaka H; Higashi E; Sakai H; Yoshida R; Kwon JT; McLeod HL; Yokoi T
Clin Pharmacol Ther; 2006 Sep; 80(3):282-97. PubMed ID: 16952495
[TBL] [Abstract][Full Text] [Related]
18. Genetic polymorphisms in the cytochrome P450 2A6 (CYP2A6) gene: implications for interindividual differences in nicotine metabolism.
Oscarson M
Drug Metab Dispos; 2001 Feb; 29(2):91-5. PubMed ID: 11159795
[TBL] [Abstract][Full Text] [Related]
19. Role of human cytochrome P4502A6 in C-oxidation of nicotine.
Nakajima M; Yamamoto T; Nunoya K; Yokoi T; Nagashima K; Inoue K; Funae Y; Shimada N; Kamataki T; Kuroiwa Y
Drug Metab Dispos; 1996 Nov; 24(11):1212-7. PubMed ID: 8937855
[TBL] [Abstract][Full Text] [Related]
20. Prediction methods for nicotine clearance using cotinine and 3-hydroxy-cotinine spot saliva samples II. Model application.
Levi M; Dempsey DA; Benowitz NL; Sheiner LB
J Pharmacokinet Pharmacodyn; 2007 Feb; 34(1):23-34. PubMed ID: 17206525
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
