112 related articles for article (PubMed ID: 10669567)
1. Successful virtual screening of a chemical database for farnesyltransferase inhibitor leads.
Perola E; Xu K; Kollmeyer TM; Kaufmann SH; Prendergast FG; Pang YP
J Med Chem; 2000 Feb; 43(3):401-8. PubMed ID: 10669567
[TBL] [Abstract][Full Text] [Related]
2. Successful molecular dynamics simulation of the zinc-bound farnesyltransferase using the cationic dummy atom approach.
Pang YP; Xu K; Yazal JE; Prendergas FG
Protein Sci; 2000 Oct; 9(10):1857-65. PubMed ID: 11106157
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and early structure-activity relationship of farnesyltransferase inhibitors which mimic both the peptidic and the prenylic substrate.
Schlitzer M; Böhm M; Sattler I; Dahse HM
Bioorg Med Chem; 2000 Aug; 8(8):1991-2006. PubMed ID: 11003144
[TBL] [Abstract][Full Text] [Related]
4. Non-peptidic, non-prenylic bisubstrate farnesyltransferase inhibitors. Part 3: structural requirements of the central moiety for farnesyltransferase inhibitory activity.
Schlitzer M; Böhm M; Sattler I
Bioorg Med Chem; 2000 Oct; 8(10):2399-406. PubMed ID: 11058034
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and characterization of piperazinedione-based dual protein inhibitors for both farnesyltransferase and geranylgeranyltransferase-I.
Qiao Y; Gao J; Qiu Y; Wu L; Guo F; Lo KK; Li D
Eur J Med Chem; 2011 Jun; 46(6):2264-73. PubMed ID: 21440964
[TBL] [Abstract][Full Text] [Related]
6. Exploration of novel aryl binding sites of farnesyltransferase using molecular modeling and benzophenone-based farnesyltransferase inhibitors.
Böhm M; Mitsch A; Wissner P; Sattler I; Schlitzer M
J Med Chem; 2001 Sep; 44(19):3117-24. PubMed ID: 11543680
[TBL] [Abstract][Full Text] [Related]
7. UCF76 compounds, new inhibitors of farnesyltransferase produced by Streptomyces.
Hara M; Soga S; Shono K; Eishima J; Mizukami T
J Antibiot (Tokyo); 2001 Feb; 54(2):182-6. PubMed ID: 11302493
[No Abstract] [Full Text] [Related]
8. Structure based design of benzophenone-based non-thiol farnesyltransferase inhibitors.
Schlitzer M
Curr Pharm Des; 2002; 8(19):1713-22. PubMed ID: 12171543
[TBL] [Abstract][Full Text] [Related]
9. Non-thiol farnesyltransferase inhibitors: the concept of benzophenone-based bisubstrate analogue farnesyltransferase inhibitors.
Schlitzer M; Sattler I
Eur J Med Chem; 2000; 35(7-8):721-6. PubMed ID: 10960188
[TBL] [Abstract][Full Text] [Related]
10. 3-Aryl-4-aryloyl-1-(1H-imidazol-5-yl)methylpyrrole, a novel class of farnesyltransferase inhibitors.
Lee H; Lee J; Shin Y; Jung W; Kim JH; Park K; Ro S; Chung HH; Koh JS
Bioorg Med Chem Lett; 2001 Nov; 11(22):2963-5. PubMed ID: 11677136
[TBL] [Abstract][Full Text] [Related]
11. Identification of mono- and bisubstrate inhibitors of protein farnesyltransferase and inducers of apoptosis from a pepticinnamin E library.
Thutewohl M; Kissau L; Popkirova B; Karaguni IM; Nowak T; Bate M; Kuhlmann J; Müller O; Waldmann H
Bioorg Med Chem; 2003 Jun; 11(12):2617-26. PubMed ID: 12757727
[TBL] [Abstract][Full Text] [Related]
12. Non-thiol farnesyltransferase inhibitors: FTase-inhibition and cellular activity of benzophenone-based bisubstrate analogue farnesyltransferase inhibitors.
Mitsch A; Bergemann S; Gust R; Sattler I; Schlitzer M
Arch Pharm (Weinheim); 2003 Jul; 336(4-5):242-50. PubMed ID: 12916059
[TBL] [Abstract][Full Text] [Related]
13. Non-thiol farnesyltransferase inhibitors: utilization of the far aryl binding site by 5-cinnamoylaminobenzophenones.
Mitsch A; Wissner P; Böhm M; Silber K; Klebe G; Sattler I; Schlitzer M
Arch Pharm (Weinheim); 2004 Sep; 337(9):493-501. PubMed ID: 15362122
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of o-trifluoromethylbiphenyl substituted 2-amino-nicotinonitriles as inhibitors of farnesyltransferase.
Wang GT; Wang X; Wang W; Hasvold LA; Sullivan G; Hutchins CW; O'Conner S; Gentiles R; Sowin T; Cohen J; Gu WZ; Zhang H; Rosenberg SH; Sham HL
Bioorg Med Chem Lett; 2005 Jan; 15(1):153-8. PubMed ID: 15582430
[TBL] [Abstract][Full Text] [Related]
15. Discovery and structure-activity relationships of novel piperidine inhibitors of farnesyltransferase.
Nara S; Tanaka R; Eishima J; Hara M; Takahashi Y; Otaki S; Foglesong RJ; Hughes PF; Turkington S; Kanda Y
J Med Chem; 2003 Jun; 46(12):2467-73. PubMed ID: 12773050
[TBL] [Abstract][Full Text] [Related]
16. Non-thiol farnesyltransferase inhibitors: N-(4-Acylamino-3-benzoylphenyl)-4-nitrocinnamic acid amides.
Sakowski J; Sattler I; Schlitzer M
Bioorg Med Chem; 2002 Feb; 10(2):233-9. PubMed ID: 11741771
[TBL] [Abstract][Full Text] [Related]
17. N-arylpiperazinone inhibitors of farnesyltransferase: discovery and biological activity.
Williams TM; Bergman JM; Brashear K; Breslin MJ; Dinsmore CJ; Hutchinson JH; MacTough SC; Stump CA; Wei DD; Zartman CB; Bogusky MJ; Culberson JC; Buser-Doepner C; Davide J; Greenberg IB; Hamilton KA; Koblan KS; Kohl NE; Liu D; Lobell RB; Mosser SD; O'Neill TJ; Rands E; Schaber MD; Huff JR
J Med Chem; 1999 Sep; 42(19):3779-84. PubMed ID: 10508426
[No Abstract] [Full Text] [Related]
18. Design, synthesis, and structure-activity relationships of tetrahydroquinoline-based farnesyltransferase inhibitors.
Lombardo LJ; Camuso A; Clark J; Fager K; Gullo-Brown J; Hunt JT; Inigo I; Kan D; Koplowitz B; Lee F; McGlinchey K; Qian L; Ricca C; Rovnyak G; Traeger S; Tokarski J; Williams DK; Wu LI; Zhao Y; Manne V; Bhide RS
Bioorg Med Chem Lett; 2005 Apr; 15(7):1895-9. PubMed ID: 15780629
[TBL] [Abstract][Full Text] [Related]
19. Non-thiol farnesyltransferase inhibitors: utilization of the near aryl binding site by 5-arylacetylaminobenzophenones.
Mitsch A; Böhm M; Sattler I; Schlitzer M
Arch Pharm (Weinheim); 2004 Apr; 337(4):213-8. PubMed ID: 15065081
[TBL] [Abstract][Full Text] [Related]
20. Farnesyl protein transferase inhibitors targeting the catalytic zinc for enhanced binding.
Njoroge FG; Vibulbhan B; Pinto P; Strickland C; Kirschmeier P; Bishop WR; Girijavallabhan V
Bioorg Med Chem Lett; 2004 Dec; 14(23):5877-80. PubMed ID: 15501060
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
