313 related articles for article (PubMed ID: 10669578)
1. New selective and potent 5-HT(1B/1D) antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides.
Liao Y; Böttcher H; Harting J; Greiner H; van Amsterdam C; Cremers T; Sundell S; März J; Rautenberg W; Wikström H
J Med Chem; 2000 Feb; 43(3):517-25. PubMed ID: 10669578
[TBL] [Abstract][Full Text] [Related]
2. 5-HT reuptake inhibitors with 5-HT(1B/1D) antagonistic activity: a new approach toward efficient antidepressants.
Matzen L; van Amsterdam C; Rautenberg W; Greiner HE; Harting J; Seyfried CA; Böttcher H
J Med Chem; 2000 Mar; 43(6):1149-57. PubMed ID: 10737747
[TBL] [Abstract][Full Text] [Related]
3. Involvement of 5-HT(1B/1D) and 5-HT2A receptors in 5-HT-induced contraction of endothelium-denuded rabbit epicardial coronary arteries.
Ellwood AJ; Curtis MJ
Br J Pharmacol; 1997 Nov; 122(5):875-84. PubMed ID: 9384503
[TBL] [Abstract][Full Text] [Related]
4. Specific labelling of serotonin 5-HT(1B) receptors in rat frontal cortex with the novel, phenylpiperazine derivative, [3H]GR125,743. A pharmacological characterization.
Millan MJ; Newman-Tancredi A; Lochon S; Touzard M; Aubry S; Audinot V
Pharmacol Biochem Behav; 2002 Apr; 71(4):589-98. PubMed ID: 11888550
[TBL] [Abstract][Full Text] [Related]
5. SB-272183, a selective 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptor antagonist in native tissue.
Watson J; Roberts C; Scott C; Kendall I; Collin L; Day NC; Harries MH; Soffin E; Davies CH; Randall AD; Heightman T; Gaster L; Wyman P; Parker C; Price GW; Middlemiss DN
Br J Pharmacol; 2001 Jul; 133(6):797-806. PubMed ID: 11454652
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and structure-activity relationships of a new model of arylpiperazines. 5. Study of the physicochemical influence of the pharmacophore on 5-HT(1a)/alpha(1)-adrenergic receptor affinity: synthesis of a new derivative with mixed 5-HT(1a)/d(2) antagonist properties.
López-Rodríguez ML; Morcillo MJ; Fernández E; Porras E; Orensanz L; Beneytez ME; Manzanares J; Fuentes JA
J Med Chem; 2001 Jan; 44(2):186-97. PubMed ID: 11170628
[TBL] [Abstract][Full Text] [Related]
7. The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
Gaster LM; Blaney FE; Davies S; Duckworth DM; Ham P; Jenkins S; Jennings AJ; Joiner GF; King FD; Mulholland KR; Wyman PA; Hagan JJ; Hatcher J; Jones BJ; Middlemiss DN; Price GW; Riley G; Roberts C; Routledge C; Selkirk J; Slade PD
J Med Chem; 1998 Apr; 41(8):1218-35. PubMed ID: 9548813
[TBL] [Abstract][Full Text] [Related]
8. In vitro activity of LY393558, an inhibitor of the 5-hydroxytryptamine transporter with 5-HT(1B/1D/2) receptor antagonist properties.
Pullar IA; Boot JR; Carney SL; Cohen ML; Colvin EM; Conway RG; Hardy CH; Lucaites VL; Nelson DL; Schenck KW; Tomlinson R; Wedley S
Eur J Pharmacol; 2001 Nov; 432(1):9-17. PubMed ID: 11734182
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and in vitro and in vivo functional studies of ortho-substituted phenylpiperazine and N-substituted 4-N-(o-methoxyphenyl)aminopiperidine analogues of WAY100635.
Mensonides-Harsema MM; Liao Y; Böttcher H; Bartoszyk GD; Greiner HE; Harting J; de Boer P; Wikström HV
J Med Chem; 2000 Feb; 43(3):432-9. PubMed ID: 10669570
[TBL] [Abstract][Full Text] [Related]
10. Synergism between 5-HT1B/1D and 5-HT1A receptor antagonists on turnover and release of 5-HT in guinea-pig brain in vivo.
Stenfors C; Magnusson T; Larsson LG; Yu H; Hållbus M; Magnusson O; Ross SB
Naunyn Schmiedebergs Arch Pharmacol; 1999 Feb; 359(2):110-6. PubMed ID: 10048595
[TBL] [Abstract][Full Text] [Related]
11. LY393558, a 5-hydroxytryptamine reuptake inhibitor and 5-HT(1B/1D) receptor antagonist: effects on extracellular levels of 5-hydroxytryptamine in the guinea pig and rat.
Mitchell SN; Greenslade RG; Cooper J
Eur J Pharmacol; 2001 Nov; 432(1):19-27. PubMed ID: 11734183
[TBL] [Abstract][Full Text] [Related]
12. F 11356, a novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors in models relevant to migraine.
John GW; Pauwels PJ; Perez M; Halazy S; Le Grand B; Verscheure Y; Valentin JP; Palmier C; Wurch T; Chopin P; Marien M; Kleven MS; Koek W; Assie MB; Carilla-Durand E; Tarayre JP; Colpaert FC
J Pharmacol Exp Ther; 1999 Jul; 290(1):83-95. PubMed ID: 10381763
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and pharmacological evaluation of 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-phenylpiperazines with clozapine-like mixed activities at dopamine D(2), serotonin, and GABA(A) receptors.
Asproni B; Pau A; Bitti M; Melosu M; Cerri R; Dazzi L; Seu E; Maciocco E; Sanna E; Busonero F; Talani G; Pusceddu L; Altomare C; Trapani G; Biggio G
J Med Chem; 2002 Oct; 45(21):4655-68. PubMed ID: 12361392
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and SAR of 3- and 4-substituted quinolin-2-ones: discovery of mixed 5-HT(1B)/5-HT(2A) receptor antagonists.
McCort G; Hoornaert C; Aletru M; Denys C; Duclos O; Cadilhac C; Guilpain E; Dellac G; Janiak P; Galzin AM; Delahaye M; Guilbert F; O'Connor S
Bioorg Med Chem; 2001 Aug; 9(8):2129-37. PubMed ID: 11504649
[TBL] [Abstract][Full Text] [Related]
15. Head and whole-body jerking in guinea pigs are differentially modulated by 5-HT1A, 5-HT1B/1D and 5-HT2A receptor antagonists.
Nielsen CK
Eur J Pharmacol; 1998 Nov; 361(2-3):185-90. PubMed ID: 9865507
[TBL] [Abstract][Full Text] [Related]
16. [N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy.
Maier DL; Sobotka-Briner C; Ding M; Powell ME; Jiang Q; Hill G; Heys JR; Elmore CS; Pierson ME; Mrzljak L
J Pharmacol Exp Ther; 2009 Jul; 330(1):342-51. PubMed ID: 19401496
[TBL] [Abstract][Full Text] [Related]
17. Influence of the endothelium and nitric oxide on the contractile responses evoked by 5-HT1D receptor agonists in the rabbit isolated saphenous vein.
Valentin JP; Bonnafous R; John GW
Br J Pharmacol; 1996 Sep; 119(1):35-42. PubMed ID: 8872354
[TBL] [Abstract][Full Text] [Related]
18. Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockade.
Roberts C; Boyd DF; Middlemiss DN; Routledge C
Neuropharmacology; 1999 Sep; 38(9):1409-19. PubMed ID: 10471095
[TBL] [Abstract][Full Text] [Related]
19. Differences in the effects of ketanserin and GR127935 on 5-HT-receptor mediated responses in rabbit saphenous vein and guinea-pig jugular vein.
Razzaque Z; Longmore J; Hill RG
Eur J Pharmacol; 1995 Sep; 283(1-3):199-206. PubMed ID: 7498311
[TBL] [Abstract][Full Text] [Related]
20. Characterization of sumatriptan-induced contractions in human isolated blood vessels using selective 5-HT(1B) and 5-HT(1D) receptor antagonists and in situ hybridization.
van den Broek RW; Bhalla P; VanDenBrink AM; de Vries R; Sharma HS; Saxena PR
Cephalalgia; 2002 Mar; 22(2):83-93. PubMed ID: 11972574
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
