BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 10675333)

  • 21. Targeted Sos1 deletion reveals its critical role in early T-cell development.
    Kortum RL; Sommers CL; Alexander CP; Pinski JM; Li W; Grinberg A; Lee J; Love PE; Samelson LE
    Proc Natl Acad Sci U S A; 2011 Jul; 108(30):12407-12. PubMed ID: 21746917
    [TBL] [Abstract][Full Text] [Related]  

  • 22. SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1.
    Qu Y; Chen Q; Lai X; Zhu C; Chen C; Zhao X; Deng R; Xu M; Yuan H; Wang Y; Yu J; Huang J
    Mol Cancer; 2014 Apr; 13():95. PubMed ID: 24775912
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Multiple decisive phosphorylation sites for the negative feedback regulation of SOS1 via ERK.
    Kamioka Y; Yasuda S; Fujita Y; Aoki K; Matsuda M
    J Biol Chem; 2010 Oct; 285(43):33540-33548. PubMed ID: 20724475
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development.
    Wang DZ; Hammond VE; Abud HE; Bertoncello I; McAvoy JW; Bowtell DD
    Genes Dev; 1997 Feb; 11(3):309-20. PubMed ID: 9030684
    [TBL] [Abstract][Full Text] [Related]  

  • 25. An activating mutation in sos-1 identifies its Dbl domain as a critical inhibitor of the epidermal growth factor receptor pathway during Caenorhabditis elegans vulval development.
    Modzelewska K; Elgort MG; Huang J; Jongeward G; Lauritzen A; Yoon CH; Sternberg PW; Moghal N
    Mol Cell Biol; 2007 May; 27(10):3695-707. PubMed ID: 17339331
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Phospholipase D and RalA cooperate with the epidermal growth factor receptor to transform 3Y1 rat fibroblasts.
    Lu Z; Hornia A; Joseph T; Sukezane T; Frankel P; Zhong M; Bychenok S; Xu L; Feig LA; Foster DA
    Mol Cell Biol; 2000 Jan; 20(2):462-7. PubMed ID: 10611224
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Understanding SOS (Son of Sevenless).
    Pierre S; Bats AS; Coumoul X
    Biochem Pharmacol; 2011 Nov; 82(9):1049-56. PubMed ID: 21787760
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling.
    Kiel C; Serrano L
    Sci Signal; 2009 Jul; 2(81):ra38. PubMed ID: 19638615
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Rare variants in SOS2 and LZTR1 are associated with Noonan syndrome.
    Yamamoto GL; Aguena M; Gos M; Hung C; Pilch J; Fahiminiya S; Abramowicz A; Cristian I; Buscarilli M; Naslavsky MS; Malaquias AC; Zatz M; Bodamer O; Majewski J; Jorge AA; Pereira AC; Kim CA; Passos-Bueno MR; Bertola DR
    J Med Genet; 2015 Jun; 52(6):413-21. PubMed ID: 25795793
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes.
    Roose JP; Mollenauer M; Ho M; Kurosaki T; Weiss A
    Mol Cell Biol; 2007 Apr; 27(7):2732-45. PubMed ID: 17283063
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs.
    Liceras-Boillos P; García-Navas R; Ginel-Picardo A; Anta B; Pérez-Andrés M; Lillo C; Gómez C; Jimeno D; Fernández-Medarde A; Baltanás FC; Santos E
    Oncogene; 2016 Dec; 35(50):6389-6402. PubMed ID: 27157612
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Sos1 rapidly associates with Grb2 and is hypophosphorylated when complexed with the EGF receptor after EGF stimulation.
    Hu Y; Bowtell DD
    Oncogene; 1996 May; 12(9):1865-72. PubMed ID: 8649846
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Shc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cells.
    Lioubin MN; Myles GM; Carlberg K; Bowtell D; Rohrschneider LR
    Mol Cell Biol; 1994 Sep; 14(9):5682-91. PubMed ID: 7520523
    [TBL] [Abstract][Full Text] [Related]  

  • 34. RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.
    Depeille P; Henricks LM; van de Ven RA; Lemmens E; Wang CY; Matli M; Werb Z; Haigis KM; Donner D; Warren R; Roose JP
    Nat Cell Biol; 2015 Jun; 17(6):804-15. PubMed ID: 26005835
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation.
    Gotoh N; Toyoda M; Shibuya M
    Mol Cell Biol; 1997 Apr; 17(4):1824-31. PubMed ID: 9121430
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase Cepsilon.
    Piiper A; Elez R; You SJ; Kronenberger B; Loitsch S; Roche S; Zeuzem S
    J Biol Chem; 2003 Feb; 278(9):7065-72. PubMed ID: 12496267
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation.
    Pierre S; Bats AS; Chevallier A; Bui LC; Ambolet-Camoit A; Garlatti M; Aggerbeck M; Barouki R; Coumoul X
    Biochem Pharmacol; 2011 Jan; 81(2):304-13. PubMed ID: 20950586
    [TBL] [Abstract][Full Text] [Related]  

  • 38. CIIA negatively regulates the Ras-Erk1/2 signaling pathway through inhibiting the Ras-specific GEF activity of SOS1.
    Hwang HS; Hwang SG; Yoon KW; Yoon JH; Roh KH; Choi EJ
    J Cell Sci; 2014 Apr; 127(Pt 8):1640-6. PubMed ID: 24522193
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Chromosomal localization of two genes encoding human ras exchange factors: SOS1 maps to the 2p22-->p16 region and SOS2 to the 14q21-->q22 region of the human genome.
    Chardin P; Mattei MG
    Cytogenet Cell Genet; 1994; 66(1):68-9. PubMed ID: 8275713
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices.
    Leshchiner ES; Parkhitko A; Bird GH; Luccarelli J; Bellairs JA; Escudero S; Opoku-Nsiah K; Godes M; Perrimon N; Walensky LD
    Proc Natl Acad Sci U S A; 2015 Feb; 112(6):1761-6. PubMed ID: 25624485
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.