These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Nakanishi K; Yoshimoto T; Tsutsui H; Okamura H Cytokine Growth Factor Rev; 2001 Mar; 12(1):53-72. PubMed ID: 11312119 [TBL] [Abstract][Full Text] [Related]
6. IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells. Tominaga K; Yoshimoto T; Torigoe K; Kurimoto M; Matsui K; Hada T; Okamura H; Nakanishi K Int Immunol; 2000 Feb; 12(2):151-60. PubMed ID: 10653850 [TBL] [Abstract][Full Text] [Related]
8. The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit. Chang JT; Segal BM; Nakanishi K; Okamura H; Shevach EM Eur J Immunol; 2000 Apr; 30(4):1113-9. PubMed ID: 10760800 [TBL] [Abstract][Full Text] [Related]
9. Interleukin-18 regulates both Th1 and Th2 responses. Nakanishi K; Yoshimoto T; Tsutsui H; Okamura H Annu Rev Immunol; 2001; 19():423-74. PubMed ID: 11244043 [TBL] [Abstract][Full Text] [Related]
10. Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cells. Verhagen CE; de Boer T ; Smits HH; Verreck FA; Wierenga EA; Kurimoto M; Lammas DA; Kumararatne DS; Sanal O; Kroon FP; van Dissel JT ; Sinigaglia F; Ottenhoff TH J Exp Med; 2000 Aug; 192(4):517-28. PubMed ID: 10952721 [TBL] [Abstract][Full Text] [Related]
12. Regulation of interleukin (IL)-18 receptor alpha chain expression on CD4(+) T cells during T helper (Th)1/Th2 differentiation. Critical downregulatory role of IL-4. Smeltz RB; Chen J; Hu-Li J; Shevach EM J Exp Med; 2001 Jul; 194(2):143-53. PubMed ID: 11457889 [TBL] [Abstract][Full Text] [Related]
13. IL-18 bridges innate and adaptive immunity through IFN-gamma and the CD134 pathway. Maxwell JR; Yadav R; Rossi RJ; Ruby CE; Weinberg AD; Aguila HL; Vella AT J Immunol; 2006 Jul; 177(1):234-45. PubMed ID: 16785519 [TBL] [Abstract][Full Text] [Related]
14. IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. Yoshimoto T; Takeda K; Tanaka T; Ohkusu K; Kashiwamura S; Okamura H; Akira S; Nakanishi K J Immunol; 1998 Oct; 161(7):3400-7. PubMed ID: 9759857 [TBL] [Abstract][Full Text] [Related]
15. A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production. Neighbors M; Xu X; Barrat FJ; Ruuls SR; Churakova T; Debets R; Bazan JF; Kastelein RA; Abrams JS; O'Garra A J Exp Med; 2001 Aug; 194(3):343-54. PubMed ID: 11489953 [TBL] [Abstract][Full Text] [Related]
16. Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: implications for the innate immune response. Fehniger TA; Shah MH; Turner MJ; VanDeusen JB; Whitman SP; Cooper MA; Suzuki K; Wechser M; Goodsaid F; Caligiuri MA J Immunol; 1999 Apr; 162(8):4511-20. PubMed ID: 10201989 [TBL] [Abstract][Full Text] [Related]
17. IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK and T cells. Sareneva T; Julkunen I; Matikainen S J Immunol; 2000 Aug; 165(4):1933-8. PubMed ID: 10925275 [TBL] [Abstract][Full Text] [Related]