121 related articles for article (PubMed ID: 10681552)
1. A network of conserved intramolecular contacts defines the off-state of the transmembrane switch mechanism in a seven-transmembrane receptor.
Lu ZL; Hulme EC
J Biol Chem; 2000 Feb; 275(8):5682-6. PubMed ID: 10681552
[TBL] [Abstract][Full Text] [Related]
2. Transmembrane domains 4 and 7 of the M(1) muscarinic acetylcholine receptor are critical for ligand binding and the receptor activation switch.
Lu ZL; Saldanha JW; Hulme EC
J Biol Chem; 2001 Sep; 276(36):34098-104. PubMed ID: 11441014
[TBL] [Abstract][Full Text] [Related]
3. Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor.
Han SJ; Hamdan FF; Kim SK; Jacobson KA; Bloodworth LM; Li B; Wess J
J Biol Chem; 2005 Oct; 280(41):34849-58. PubMed ID: 16093246
[TBL] [Abstract][Full Text] [Related]
4. Structure and activation of muscarinic acetylcholine receptors.
Hulme EC; Lu ZL; Saldanha JW; Bee MS
Biochem Soc Trans; 2003 Feb; 31(Pt 1):29-34. PubMed ID: 12546648
[TBL] [Abstract][Full Text] [Related]
5. Use of an in situ disulfide cross-linking strategy to map proximities between amino acid residues in transmembrane domains I and VII of the M3 muscarinic acetylcholine receptor.
Hamdan FF; Ward SD; Siddiqui NA; Bloodworth LM; Wess J
Biochemistry; 2002 Jun; 41(24):7647-58. PubMed ID: 12056896
[TBL] [Abstract][Full Text] [Related]
6. The conformational switch in muscarinic acetylcholine receptors.
Hulme EC; Lu ZL; Bee M; Curtis CA; Saldanha J
Life Sci; 2001 Apr; 68(22-23):2495-500. PubMed ID: 11392618
[TBL] [Abstract][Full Text] [Related]
7. The functional topography of transmembrane domain 3 of the M1 muscarinic acetylcholine receptor, revealed by scanning mutagenesis.
Lu ZL; Hulme EC
J Biol Chem; 1999 Mar; 274(11):7309-15. PubMed ID: 10066794
[TBL] [Abstract][Full Text] [Related]
8. Alanine-scanning mutagenesis of transmembrane domain 6 of the M(1) muscarinic acetylcholine receptor suggests that Tyr381 plays key roles in receptor function.
Ward SD; Curtis CA; Hulme EC
Mol Pharmacol; 1999 Nov; 56(5):1031-41. PubMed ID: 10531410
[TBL] [Abstract][Full Text] [Related]
9. Scanning mutagenesis identifies amino acid side chains in transmembrane domain 5 of the M(1) muscarinic receptor that participate in binding the acetyl methyl group of acetylcholine.
Allman K; Page KM; Curtis CA; Hulme EC
Mol Pharmacol; 2000 Jul; 58(1):175-84. PubMed ID: 10860940
[TBL] [Abstract][Full Text] [Related]
10. Seven-transmembrane receptors: crystals clarify.
Lu ZL; Saldanha JW; Hulme EC
Trends Pharmacol Sci; 2002 Mar; 23(3):140-6. PubMed ID: 11879682
[TBL] [Abstract][Full Text] [Related]
11. Identification of a ligand-dependent switch within a muscarinic receptor.
Spalding TA; Burstein ES; Henderson SC; Ducote KR; Brann MR
J Biol Chem; 1998 Aug; 273(34):21563-8. PubMed ID: 9705286
[TBL] [Abstract][Full Text] [Related]
12. Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1: noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor.
Jensen AA; Sheppard PO; Jensen LB; O'Hara PJ; Bräuner-Osborne H
J Biol Chem; 2001 Mar; 276(13):10110-8. PubMed ID: 11133983
[TBL] [Abstract][Full Text] [Related]
13. Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast. Identification of point mutations that "silence" a constitutively active mutant M3 receptor and greatly impair receptor/G protein coupling.
Schmidt C; Li B; Bloodworth L; Erlenbach I; Zeng FY; Wess J
J Biol Chem; 2003 Aug; 278(32):30248-60. PubMed ID: 12750375
[TBL] [Abstract][Full Text] [Related]
14. The conformational switch in 7-transmembrane receptors: the muscarinic receptor paradigm.
Hulme EC; Lu ZL; Ward SD; Allman K; Curtis CA
Eur J Pharmacol; 1999 Jun; 375(1-3):247-60. PubMed ID: 10443581
[TBL] [Abstract][Full Text] [Related]
15. Connectivity and orientation of the seven helical bundle in the tachykinin NK-1 receptor probed by zinc site engineering.
Elling CE; Schwartz TW
EMBO J; 1996 Nov; 15(22):6213-9. PubMed ID: 8947044
[TBL] [Abstract][Full Text] [Related]
16. Complex of an active mu-opioid receptor with a cyclic peptide agonist modeled from experimental constraints.
Fowler CB; Pogozheva ID; Lomize AL; LeVine H; Mosberg HI
Biochemistry; 2004 Dec; 43(50):15796-810. PubMed ID: 15595835
[TBL] [Abstract][Full Text] [Related]
17. Conserved extracellular cysteine pair in the M3 muscarinic acetylcholine receptor is essential for proper receptor cell surface localization but not for G protein coupling.
Zeng FY; Soldner A; Schöneberg T; Wess J
J Neurochem; 1999 Jun; 72(6):2404-14. PubMed ID: 10349850
[TBL] [Abstract][Full Text] [Related]
18. Gonadotropin-Releasing Hormone (GnRH) Receptor Structure and GnRH Binding.
Flanagan CA; Manilall A
Front Endocrinol (Lausanne); 2017; 8():274. PubMed ID: 29123501
[TBL] [Abstract][Full Text] [Related]
19. Structure of a G-protein-coupling domain of a muscarinic receptor predicted by random saturation mutagenesis.
Hill-Eubanks D; Burstein ES; Spalding TA; Bräuner-Osborne H; Brann MR
J Biol Chem; 1996 Feb; 271(6):3058-65. PubMed ID: 8621701
[TBL] [Abstract][Full Text] [Related]
20. Insertion mutagenesis as a tool to predict the secondary structure of a muscarinic receptor domain determining specificity of G-protein coupling.
Blüml K; Mutschler E; Wess J
Proc Natl Acad Sci U S A; 1994 Aug; 91(17):7980-4. PubMed ID: 8058746
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
