202 related articles for article (PubMed ID: 10681574)
1. Partitioning of serpin-proteinase reactions between stable inhibition and substrate cleavage is regulated by the rate of serpin reactive center loop insertion into beta-sheet A.
Lawrence DA; Olson ST; Muhammad S; Day DE; Kvassman JO; Ginsburg D; Shore JD
J Biol Chem; 2000 Feb; 275(8):5839-44. PubMed ID: 10681574
[TBL] [Abstract][Full Text] [Related]
2. A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism.
Egelund R; Petersen TE; Andreasen PA
Eur J Biochem; 2001 Feb; 268(3):673-85. PubMed ID: 11168406
[TBL] [Abstract][Full Text] [Related]
3. Resolution of Michaelis complex, acylation, and conformational change steps in the reactions of the serpin, plasminogen activator inhibitor-1, with tissue plasminogen activator and trypsin.
Olson ST; Swanson R; Day D; Verhamme I; Kvassman J; Shore JD
Biochemistry; 2001 Oct; 40(39):11742-56. PubMed ID: 11570875
[TBL] [Abstract][Full Text] [Related]
4. Conformational changes of the reactive-centre loop and beta-strand 5A accompany temperature-dependent inhibitor-substrate transition of plasminogen-activator inhibitor 1.
Kjøller L; Martensen PM; Sottrup-Jensen L; Justesen J; Rodenburg KW; Andreasen PA
Eur J Biochem; 1996 Oct; 241(1):38-46. PubMed ID: 8898886
[TBL] [Abstract][Full Text] [Related]
5. Interaction between the P14 residue and strand 2 of beta-sheet B is critical for reactive center loop insertion in plasminogen activator inhibitor-2.
Saunders DN; Jankova L; Harrop SJ; Curmi PM; Gould AR; Ranson M; Baker MS
J Biol Chem; 2001 Nov; 276(46):43383-9. PubMed ID: 11555638
[TBL] [Abstract][Full Text] [Related]
6. Mutation of the highly conserved tryptophan in the serpin breach region alters the inhibitory mechanism of plasminogen activator inhibitor-1.
Blouse GE; Perron MJ; Kvassman JO; Yunus S; Thompson JH; Betts RL; Lutter LC; Shore JD
Biochemistry; 2003 Oct; 42(42):12260-72. PubMed ID: 14567688
[TBL] [Abstract][Full Text] [Related]
7. The pH dependence of serpin-proteinase complex dissociation reveals a mechanism of complex stabilization involving inactive and active conformational states of the proteinase which are perturbable by calcium.
Calugaru SV; Swanson R; Olson ST
J Biol Chem; 2001 Aug; 276(35):32446-55. PubMed ID: 11404362
[TBL] [Abstract][Full Text] [Related]
8. Rational design of complex formation between plasminogen activator inhibitor-1 and its target proteinases.
Aertgeerts K; De Ranter CJ; Booth NA; Declerck PJ
J Struct Biol; 1997 Apr; 118(3):236-42. PubMed ID: 9169233
[TBL] [Abstract][Full Text] [Related]
9. Formation of the covalent chymotrypsin.antichymotrypsin complex involves no large-scale movement of the enzyme.
O'Malley KM; Cooperman BS
J Biol Chem; 2001 Mar; 276(9):6631-9. PubMed ID: 11027695
[TBL] [Abstract][Full Text] [Related]
10. A concerted structural transition in the plasminogen activator inhibitor-1 mechanism of inhibition.
Blouse GE; Perron MJ; Thompson JH; Day DE; Link CA; Shore JD
Biochemistry; 2002 Oct; 41(40):11997-2009. PubMed ID: 12356300
[TBL] [Abstract][Full Text] [Related]
11. Apparent formation of sodium dodecyl sulfate-stable complexes between serpins and 3,4-dichloroisocoumarin-inactivated proteinases is due to regeneration of active proteinase from the inactivated enzyme.
Olson ST; Swanson R; Patston PA; Björk I
J Biol Chem; 1997 May; 272(20):13338-42. PubMed ID: 9148956
[TBL] [Abstract][Full Text] [Related]
12. Structural and inhibitory effects of hinge loop mutagenesis in serpin-2 from the malaria vector Anopheles gambiae.
Zhang X; Meekins DA; An C; Zolkiewski M; Battaile KP; Kanost MR; Lovell S; Michel K
J Biol Chem; 2015 Jan; 290(5):2946-56. PubMed ID: 25525260
[TBL] [Abstract][Full Text] [Related]
13. Understanding the specificity of serpin-protease complexes through interface analysis.
Rashid Q; Kapil C; Singh P; Kumari V; Jairajpuri MA
J Biomol Struct Dyn; 2015; 33(6):1352-62. PubMed ID: 25052369
[TBL] [Abstract][Full Text] [Related]
14. Formation of a noncovalent serpin-proteinase complex involves no conformational change in the serpin. Use of 1H-15N HSQC NMR as a sensitive nonperturbing monitor of conformation.
Peterson FC; Gordon NC; Gettins PG
Biochemistry; 2000 Oct; 39(39):11884-92. PubMed ID: 11009600
[TBL] [Abstract][Full Text] [Related]
15. Inhibitory mechanism of serpins: loop insertion forces acylation of plasminogen activator by plasminogen activator inhibitor-1.
Kvassman JO; Verhamme I; Shore JD
Biochemistry; 1998 Nov; 37(44):15491-502. PubMed ID: 9799512
[TBL] [Abstract][Full Text] [Related]
16. The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions.
Schreuder HA; de Boer B; Dijkema R; Mulders J; Theunissen HJ; Grootenhuis PD; Hol WG
Nat Struct Biol; 1994 Jan; 1(1):48-54. PubMed ID: 7656006
[TBL] [Abstract][Full Text] [Related]
17. Serpin conformational change in ovalbumin. Enhanced reactive center loop insertion through hinge region mutations.
Huntington JA; Fan B; Karlsson KE; Deinum J; Lawrence DA; Gettins PG
Biochemistry; 1997 May; 36(18):5432-40. PubMed ID: 9154925
[TBL] [Abstract][Full Text] [Related]
18. Reactive centre loop dynamics and serpin specificity.
Marijanovic EM; Fodor J; Riley BT; Porebski BT; Costa MGS; Kass I; Hoke DE; McGowan S; Buckle AM
Sci Rep; 2019 Mar; 9(1):3870. PubMed ID: 30846766
[TBL] [Abstract][Full Text] [Related]
19. Preparative induction and characterization of L-antithrombin: a structural homologue of latent plasminogen activator inhibitor-1.
Wardell MR; Chang WS; Bruce D; Skinner R; Lesk AM; Carrell RW
Biochemistry; 1997 Oct; 36(42):13133-42. PubMed ID: 9335576
[TBL] [Abstract][Full Text] [Related]
20. Type-1 plasminogen-activator inhibitor -- conformational differences between latent, active, reactive-centre-cleaved and plasminogen-activator-complexed forms, as probed by proteolytic susceptibility.
Egelund R; Schousboe SL; Sottrup-Jensen L; Rodenburg KW; Andreasen PA
Eur J Biochem; 1997 Sep; 248(3):775-85. PubMed ID: 9342229
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]