BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 10683371)

  • 1. Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581.
    Tomasson MH; Sternberg DW; Williams IR; Carroll M; Cain D; Aster JC; Ilaria RL; Van Etten RA; Gilliland DG
    J Clin Invest; 2000 Feb; 105(4):423-32. PubMed ID: 10683371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TEL/PDGFbetaR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor.
    Tomasson MH; Williams IR; Hasserjian R; Udomsakdi C; McGrath SM; Schwaller J; Druker B; Gilliland DG
    Blood; 1999 Mar; 93(5):1707-14. PubMed ID: 10029600
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia.
    Liu Q; Schwaller J; Kutok J; Cain D; Aster JC; Williams IR; Gilliland DG
    EMBO J; 2000 Apr; 19(8):1827-38. PubMed ID: 10775267
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Signaling in leukemia: which messenger to kill?
    Pear WS
    J Clin Invest; 2000 Feb; 105(4):419-22. PubMed ID: 10683370
    [No Abstract]   [Full Text] [Related]  

  • 5. The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways.
    Sternberg DW; Tomasson MH; Carroll M; Curley DP; Barker G; Caprio M; Wilbanks A; Kazlauskas A; Gilliland DG
    Blood; 2001 Dec; 98(12):3390-7. PubMed ID: 11719379
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Tel-PDGFRbeta fusion gene produces a chronic myeloproliferative syndrome in transgenic mice.
    Ritchie KA; Aprikyan AA; Bowen-Pope DF; Norby-Slycord CJ; Conyers S; Bartelmez S; Sitnicka EH; Hickstein DD
    Leukemia; 1999 Nov; 13(11):1790-803. PubMed ID: 10557054
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: a common mechanism for transformation by tyrosine kinase fusion proteins.
    Wilbanks AM; Mahajan S; Frank DA; Druker BJ; Gilliland DG; Carroll M
    Exp Hematol; 2000 May; 28(5):584-93. PubMed ID: 10812249
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage.
    Cain JA; Xiang Z; O'Neal J; Kreisel F; Colson A; Luo H; Hennighausen L; Tomasson MH
    Blood; 2007 May; 109(9):3906-14. PubMed ID: 17218386
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways.
    Carroll M; Tomasson MH; Barker GF; Golub TR; Gilliland DG
    Proc Natl Acad Sci U S A; 1996 Dec; 93(25):14845-50. PubMed ID: 8962143
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity.
    Buijs A; van Rompaey L; Molijn AC; Davis JN; Vertegaal AC; Potter MD; Adams C; van Baal S; Zwarthoff EC; Roussel MF; Grosveld GC
    Mol Cell Biol; 2000 Dec; 20(24):9281-93. PubMed ID: 11094079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia.
    Magnusson MK; Meade KE; Brown KE; Arthur DC; Krueger LA; Barrett AJ; Dunbar CE
    Blood; 2001 Oct; 98(8):2518-25. PubMed ID: 11588050
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells.
    Lacronique V; Boureux A; Monni R; Dumon S; Mauchauffé M; Mayeux P; Gouilleux F; Berger R; Gisselbrecht S; Ghysdael J; Bernard OA
    Blood; 2000 Mar; 95(6):2076-83. PubMed ID: 10706877
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Positive and negative regulatory roles of the WW-like domain in TEL-PDGFbetaR transformation.
    Chen J; Williams IR; Kutok JL; Duclos N; Anastasiadou E; Masters SC; Fu H; Gilliland DG
    Blood; 2004 Jul; 104(2):535-42. PubMed ID: 15054045
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of myeloproliferative disease in mice by tyrosine kinase fusion oncogenes does not require granulocyte-macrophage colony-stimulating factor or interleukin-3.
    Tomasson MH; Williams IR; Li S; Kutok J; Cain D; Gillessen S; Dranoff G; Van Etten RA; Gilliland DG
    Blood; 2001 Mar; 97(5):1435-41. PubMed ID: 11222391
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The coupling of TEL/PDGFbetaR to distinct functional responses is modulated by the presence of cytokine: involvement of mitogen-activated protein kinases.
    Wheadon H; Welham MJ
    Blood; 2003 Aug; 102(4):1480-9. PubMed ID: 12714513
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fusion of Huntingtin interacting protein 1 to platelet-derived growth factor beta receptor (PDGFbetaR) in chronic myelomonocytic leukemia with t(5;7)(q33;q11.2).
    Ross TS; Bernard OA; Berger R; Gilliland DG
    Blood; 1998 Jun; 91(12):4419-26. PubMed ID: 9616134
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transforming properties of the Huntingtin interacting protein 1/ platelet-derived growth factor beta receptor fusion protein.
    Ross TS; Gilliland DG
    J Biol Chem; 1999 Aug; 274(32):22328-36. PubMed ID: 10428802
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice.
    Grisolano JL; O'Neal J; Cain J; Tomasson MH
    Proc Natl Acad Sci U S A; 2003 Aug; 100(16):9506-11. PubMed ID: 12881486
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stable expression of small interfering RNA sensitizes TEL-PDGFbetaR to inhibition with imatinib or rapamycin.
    Chen J; Wall NR; Kocher K; Duclos N; Fabbro D; Neuberg D; Griffin JD; Shi Y; Gilliland DG
    J Clin Invest; 2004 Jun; 113(12):1784-91. PubMed ID: 15199413
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes.
    Schwaller J; Frantsve J; Aster J; Williams IR; Tomasson MH; Ross TS; Peeters P; Van Rompaey L; Van Etten RA; Ilaria R; Marynen P; Gilliland DG
    EMBO J; 1998 Sep; 17(18):5321-33. PubMed ID: 9736611
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.