599 related articles for article (PubMed ID: 10683375)
21. Role of inflammatory infiltrate in activation and effector function of cloned islet reactive nonobese diabetic CD8+ T cells: involvement of a nitric oxide-dependent pathway.
Gurlo T; Kawamura K; von Grafenstein H
J Immunol; 1999 Dec; 163(11):5770-80. PubMed ID: 10570259
[TBL] [Abstract][Full Text] [Related]
22. Perforin-dependent cytotoxic activity and lymphokine secretion by CD4+ T cells are regulated by CD8+ T cells.
Williams NS; Engelhard VH
J Immunol; 1997 Sep; 159(5):2091-9. PubMed ID: 9278294
[TBL] [Abstract][Full Text] [Related]
23. Both CD4(+)and CD8(+)T cells are required for IFN-gamma gene expression in pancreatic islets and autoimmune diabetes development in biobreeding rats.
El-Sheikh A; Suarez-Pinzon WL; Power RF; Rabinovitch A
J Autoimmun; 1999 Mar; 12(2):109-19. PubMed ID: 10047431
[TBL] [Abstract][Full Text] [Related]
24. I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice.
Noorchashm H; Lieu YK; Noorchashm N; Rostami SY; Greeley SA; Schlachterman A; Song HK; Noto LE; Jevnikar AM; Barker CF; Naji A
J Immunol; 1999 Jul; 163(2):743-50. PubMed ID: 10395666
[TBL] [Abstract][Full Text] [Related]
25. IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes.
Thomas HE; Parker JL; Schreiber RD; Kay TW
J Clin Invest; 1998 Sep; 102(6):1249-57. PubMed ID: 9739059
[TBL] [Abstract][Full Text] [Related]
26. IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma.
Trembleau S; Penna G; Gregori S; Giarratana N; Adorini L
J Immunol; 2003 Jun; 170(11):5491-501. PubMed ID: 12759426
[TBL] [Abstract][Full Text] [Related]
27. Abrogation of autoimmune diabetes in nonobese diabetic mice and protection against effector lymphocytes by transgenic paracrine TGF-beta1.
Moritani M; Yoshimoto K; Wong SF; Tanaka C; Yamaoka T; Sano T; Komagata Y; Miyazaki J; Kikutani H; Itakura M
J Clin Invest; 1998 Aug; 102(3):499-506. PubMed ID: 9691086
[TBL] [Abstract][Full Text] [Related]
28. Essential role for signal transducer and activator of transcription-1 in pancreatic beta-cell death and autoimmune type 1 diabetes of nonobese diabetic mice.
Kim S; Kim HS; Chung KW; Oh SH; Yun JW; Im SH; Lee MK; Kim KW; Lee MS
Diabetes; 2007 Oct; 56(10):2561-8. PubMed ID: 17620422
[TBL] [Abstract][Full Text] [Related]
29. Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.
Seewaldt S; Thomas HE; Ejrnaes M; Christen U; Wolfe T; Rodrigo E; Coon B; Michelsen B; Kay TW; von Herrath MG
Diabetes; 2000 Nov; 49(11):1801-9. PubMed ID: 11078446
[TBL] [Abstract][Full Text] [Related]
30. Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively.
Hashimoto W; Osaki T; Okamura H; Robbins PD; Kurimoto M; Nagata S; Lotze MT; Tahara H
J Immunol; 1999 Jul; 163(2):583-9. PubMed ID: 10395644
[TBL] [Abstract][Full Text] [Related]
31. In vivo blockade of the Fas-Fas ligand pathway inhibits cyclophosphamide-induced diabetes in NOD mice.
Mahiou J; Walter U; Lepault F; Godeau F; Bach JF; Chatenoud L
J Autoimmun; 2001 Jun; 16(4):431-40. PubMed ID: 11437491
[TBL] [Abstract][Full Text] [Related]
32. In vivo effects of cytokines on pancreatic beta-cells in models of type I diabetes dependent on CD4(+) T lymphocytes.
Angstetra E; Graham KL; Emmett S; Dudek NL; Darwiche R; Ayala-Perez R; Allison J; Santamaria P; Kay TW; Thomas HE
Immunol Cell Biol; 2009 Feb; 87(2):178-85. PubMed ID: 19015667
[TBL] [Abstract][Full Text] [Related]
33. Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate.
Zhao Y; Scott NA; Quah HS; Krishnamurthy B; Bond F; Loudovaris T; Mannering SI; Kay TW; Thomas HE
Eur J Immunol; 2015 Sep; 45(9):2494-503. PubMed ID: 25959978
[TBL] [Abstract][Full Text] [Related]
34. Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction.
Suarez-Pinzon W; Rajotte RV; Mosmann TR; Rabinovitch A
Diabetes; 1996 Oct; 45(10):1350-7. PubMed ID: 8826970
[TBL] [Abstract][Full Text] [Related]
35. Perforin and Fas induced by IFNgamma and TNFalpha mediate beta cell death by OT-I CTL.
McKenzie MD; Dudek NL; Mariana L; Chong MM; Trapani JA; Kay TW; Thomas HE
Int Immunol; 2006 Jun; 18(6):837-46. PubMed ID: 16574667
[TBL] [Abstract][Full Text] [Related]
36. Fas and Fas ligand immunolocalization in pancreatic islets of NOD mice during spontaneous and cyclophosphamide-accelerated diabetes.
Redd S; Ginn S; Ross JM
Histochem J; 2002; 34(1-2):1-12. PubMed ID: 12365794
[TBL] [Abstract][Full Text] [Related]
37. Prevention of autoimmune diabetes in NOD mice by troglitazone is associated with modulation of ICAM-1 expression on pancreatic islet cells and IFN-gamma expression in splenic T cells.
Augstein P; Dunger A; Heinke P; Wachlin G; Berg S; Hehmke B; Salzsieder E
Biochem Biophys Res Commun; 2003 May; 304(2):378-84. PubMed ID: 12711326
[TBL] [Abstract][Full Text] [Related]
38. In vivo diabetogenic action of CD4+ T lymphocytes requires Fas expression and is independent of IL-1 and IL-18.
Wen L; Green EA; Stratmann T; Panosa A; Gomis R; Eynon EE; Flavell RA; Mezquita JA; Mora C
Eur J Immunol; 2011 May; 41(5):1344-51. PubMed ID: 21469125
[TBL] [Abstract][Full Text] [Related]
39. Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.
Chong MM; Chen Y; Darwiche R; Dudek NL; Irawaty W; Santamaria P; Allison J; Kay TW; Thomas HE
J Immunol; 2004 May; 172(9):5714-21. PubMed ID: 15100317
[TBL] [Abstract][Full Text] [Related]
40. Cytotoxic T-cells from T-cell receptor transgenic NOD8.3 mice destroy beta-cells via the perforin and Fas pathways.
Dudek NL; Thomas HE; Mariana L; Sutherland RM; Allison J; Estella E; Angstetra E; Trapani JA; Santamaria P; Lew AM; Kay TW
Diabetes; 2006 Sep; 55(9):2412-8. PubMed ID: 16936188
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
