These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 10686104)

  • 1. Backbone dynamics of a cbEGF domain pair in the presence of calcium.
    Werner JM; Knott V; Handford PA; Campbell ID; Downing AK
    J Mol Biol; 2000 Mar; 296(4):1065-78. PubMed ID: 10686104
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of the N2144S mutation on backbone dynamics of a TB-cbEGF domain pair from human fibrillin-1.
    Yuan X; Werner JM; Lack J; Knott V; Handford PA; Campbell ID; Downing AK
    J Mol Biol; 2002 Feb; 316(1):113-25. PubMed ID: 11829507
    [TBL] [Abstract][Full Text] [Related]  

  • 3. EGF-like domain calcium affinity modulated by N-terminal domain linkage in human fibrillin-1.
    Smallridge RS; Whiteman P; Doering K; Handford PA; Downing AK
    J Mol Biol; 1999 Feb; 286(3):661-8. PubMed ID: 10024441
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Solution structure and dynamics of a calcium binding epidermal growth factor-like domain pair from the neonatal region of human fibrillin-1.
    Smallridge RS; Whiteman P; Werner JM; Campbell ID; Handford PA; Downing AK
    J Biol Chem; 2003 Apr; 278(14):12199-206. PubMed ID: 12511552
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metal ion dependency of microfibrils supports a rod-like conformation for fibrillin-1 calcium-binding epidermal growth factor-like domains.
    Cardy CM; Handford PA
    J Mol Biol; 1998 Mar; 276(5):855-60. PubMed ID: 9566191
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A G1127S change in calcium-binding epidermal growth factor-like domain 13 of human fibrillin-1 causes short range conformational effects.
    Whiteman P; Smallridge RS; Knott V; Cordle JJ; Downing AK; Handford PA
    J Biol Chem; 2001 May; 276(20):17156-62. PubMed ID: 11278305
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fibrillin-1, a calcium binding protein of extracellular matrix.
    Handford PA
    Biochim Biophys Acta; 2000 Dec; 1498(2-3):84-90. PubMed ID: 11108952
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular effects of calcium binding mutations in Marfan syndrome depend on domain context.
    McGettrick AJ; Knott V; Willis A; Handford PA
    Hum Mol Genet; 2000 Aug; 9(13):1987-94. PubMed ID: 10942427
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Defective calcium binding to fibrillin-1: consequence of an N2144S change for fibrillin-1 structure and function.
    Kettle S; Yuan X; Grundy G; Knott V; Downing AK; Handford PA
    J Mol Biol; 1999 Jan; 285(3):1277-87. PubMed ID: 9887276
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NMR analysis of cbEGF domains gives new insights into the structural consequences of a P1148A substitution in fibrillin-1.
    Whiteman P; Downing AK; Handford PA
    Protein Eng; 1998 Nov; 11(11):957-9. PubMed ID: 9876915
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cellular and molecular studies of Marfan syndrome mutations identify co-operative protein folding in the cbEGF12-13 region of fibrillin-1.
    Whiteman P; Willis AC; Warner A; Brown J; Redfield C; Handford PA
    Hum Mol Genet; 2007 Apr; 16(8):907-18. PubMed ID: 17324963
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Calcium binding properties of an epidermal growth factor-like domain pair from human fibrillin-1.
    Knott V; Downing AK; Cardy CM; Handford P
    J Mol Biol; 1996 Jan; 255(1):22-7. PubMed ID: 8568869
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural consequences of cysteine substitutions C1977Y and C1977R in calcium-binding epidermal growth factor-like domain 30 of human fibrillin-1.
    Suk JY; Jensen S; McGettrick A; Willis AC; Whiteman P; Redfield C; Handford PA
    J Biol Chem; 2004 Dec; 279(49):51258-65. PubMed ID: 15371449
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Engineered mutations in fibrillin-1 leading to Marfan syndrome act at the protein, cellular and organismal levels.
    Zeyer KA; Reinhardt DP
    Mutat Res Rev Mutat Res; 2015; 765():7-18. PubMed ID: 26281765
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular effects of homocysteine on cbEGF domain structure: insights into the pathogenesis of homocystinuria.
    Hutchinson S; Aplin RT; Webb H; Kettle S; Timmermans J; Boers GH; Handford PA
    J Mol Biol; 2005 Feb; 346(3):833-44. PubMed ID: 15713466
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Solution structure of the LDL receptor EGF-AB pair: a paradigm for the assembly of tandem calcium binding EGF domains.
    Saha S; Boyd J; Werner JM; Knott V; Handford PA; Campbell ID; Downing AK
    Structure; 2001 Jun; 9(6):451-6. PubMed ID: 11435110
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Gly --> Ser change causes defective folding in vitro of calcium-binding epidermal growth factor-like domains from factor IX and fibrillin-1.
    Whiteman P; Downing AK; Smallridge R; Winship PR; Handford PA
    J Biol Chem; 1998 Apr; 273(14):7807-13. PubMed ID: 9525872
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The calcium binding properties and molecular organization of epidermal growth factor-like domains in human fibrillin-1.
    Handford P; Downing AK; Rao Z; Hewett DR; Sykes BC; Kielty CM
    J Biol Chem; 1995 Mar; 270(12):6751-6. PubMed ID: 7896820
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
    Downing AK; Knott V; Werner JM; Cardy CM; Campbell ID; Handford PA
    Cell; 1996 May; 85(4):597-605. PubMed ID: 8653794
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bovine model of Marfan syndrome results from an amino acid change (c.3598G > A, p.E1200K) in a calcium-binding epidermal growth factor-like domain of fibrillin-1.
    Singleton AC; Mitchell AL; Byers PH; Potter KA; Pace JM
    Hum Mutat; 2005 Apr; 25(4):348-52. PubMed ID: 15776436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.