BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

343 related articles for article (PubMed ID: 10688619)

  • 1. Effects of age on in vitro midazolam biotransformation in male CD-1 mouse liver microsomes.
    Warrington JS; Poku JW; von Moltke LL; Shader RI; Harmatz JS; Greenblatt DJ
    J Pharmacol Exp Ther; 2000 Mar; 292(3):1024-31. PubMed ID: 10688619
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms.
    Perloff MD; von Moltke LL; Court MH; Kotegawa T; Shader RI; Greenblatt DJ
    J Pharmacol Exp Ther; 2000 Feb; 292(2):618-28. PubMed ID: 10640299
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential metabolism of midazolam in mouse liver and intestine microsomes: a comparison of cytochrome P450 activity and expression.
    Perloff MD; Von Moltke LL; Greenblatt DJ
    Xenobiotica; 2003 Apr; 33(4):365-77. PubMed ID: 12745872
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone.
    Mäenpää J; Hall SD; Ring BJ; Strom SC; Wrighton SA
    Pharmacogenetics; 1998 Apr; 8(2):137-55. PubMed ID: 10022752
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytochrome P450-dependent metabolism of midazolam in hepatic microsomes from chickens, turkeys, pheasant and bobwhite quail.
    Cortright KA; Craigmill AL
    J Vet Pharmacol Ther; 2006 Dec; 29(6):469-76. PubMed ID: 17083450
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A; Satoh H; Thomas PE; Bush E; Moore D
    Drug Metab Dispos; 1996 Sep; 24(9):940-7. PubMed ID: 8886602
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prediction of midazolam-CYP3A inhibitors interaction in the human liver from in vivo/in vitro absorption, distribution, and metabolism data.
    Yamano K; Yamamoto K; Katashima M; Kotaki H; Takedomi S; Matsuo H; Ohtani H; Sawada Y; Iga T
    Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):443-52. PubMed ID: 11259329
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity.
    Gorski JC; Vannaprasaht S; Hamman MA; Ambrosius WT; Bruce MA; Haehner-Daniels B; Hall SD
    Clin Pharmacol Ther; 2003 Sep; 74(3):275-87. PubMed ID: 12966371
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effect of age on sildenafil biotransformation in rat and mouse liver microsomes.
    Warrington JS; von Moltke LL; Harmatz JS; Shader RI; Greenblatt DJ
    Drug Metab Dispos; 2003 Nov; 31(11):1306-9. PubMed ID: 14570760
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of age on in vitro triazolam biotransformation in male human liver microsomes.
    Patki KC; von Moltke LL; Harmatz JS; Hesse LM; Court MH; Greenblatt DJ
    J Pharmacol Exp Ther; 2004 Mar; 308(3):874-9. PubMed ID: 14634046
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vivo comparisons of constitutive cytochrome P450 3A activity assessed by alprazolam, triazolam, and midazolam.
    Masica AL; Mayo G; Wilkinson GR
    Clin Pharmacol Ther; 2004 Oct; 76(4):341-9. PubMed ID: 15470333
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alprazolam-ritonavir interaction: implications for product labeling.
    Greenblatt DJ; von Moltke LL; Harmatz JS; Durol AL; Daily JP; Graf JA; Mertzanis P; Hoffman JL; Shader RI
    Clin Pharmacol Ther; 2000 Apr; 67(4):335-41. PubMed ID: 10801241
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unchanged cytochrome P450 3A (CYP3A) expression and metabolism of midazolam, triazolam, and dexamethasone in mdr(-/-) mouse liver microsomes.
    Perloff MD; von Moltke LL; Cotreau MM; Greenblatt DJ
    Biochem Pharmacol; 1999 Jun; 57(11):1227-32. PubMed ID: 10230766
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.
    Paine MF; Khalighi M; Fisher JM; Shen DD; Kunze KL; Marsh CL; Perkins JD; Thummel KE
    J Pharmacol Exp Ther; 1997 Dec; 283(3):1552-62. PubMed ID: 9400033
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor.
    Zhang Y; Guo X; Lin ET; Benet LZ
    Drug Metab Dispos; 1998 Apr; 26(4):360-6. PubMed ID: 9531525
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole.
    von Moltke LL; Greenblatt DJ; Harmatz JS; Duan SX; Harrel LM; Cotreau-Bibbo MM; Pritchard GA; Wright CE; Shader RI
    J Pharmacol Exp Ther; 1996 Feb; 276(2):370-9. PubMed ID: 8632299
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.
    Tsunoda SM; Velez RL; von Moltke LL; Greenblatt DJ
    Clin Pharmacol Ther; 1999 Nov; 66(5):461-71. PubMed ID: 10579473
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes.
    Zhu M; Zhao W; Jimenez H; Zhang D; Yeola S; Dai R; Vachharajani N; Mitroka J
    Drug Metab Dispos; 2005 Apr; 33(4):500-7. PubMed ID: 15640381
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The roles of CYP3A and CYP2B isoforms in hepatic bioactivation and detoxification of the pyrrolizidine alkaloid senecionine in sheep and hamsters.
    Huan JY; Miranda CL; Buhler DR; Cheeke PR
    Toxicol Appl Pharmacol; 1998 Aug; 151(2):229-35. PubMed ID: 9707499
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.