BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 10696794)

  • 1. Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-L-cysteine in freshly isolated human proximal tubular cells.
    Cummings BS; Lash LH
    Toxicol Sci; 2000 Feb; 53(2):458-66. PubMed ID: 10696794
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytotoxicity of trichloroethylene and S-(1, 2-dichlorovinyl)-L-cysteine in primary cultures of rat renal proximal tubular and distal tubular cells.
    Cummings BS; Zangar RC; Novak RF; Lash LH
    Toxicology; 2000 Sep; 150(1-3):83-98. PubMed ID: 10996665
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Roles of necrosis, Apoptosis, and mitochondrial dysfunction in S-(1,2-dichlorovinyl)-L-cysteine sulfoxide-induced cytotoxicity in primary cultures of human renal proximal tubular cells.
    Lash LH; Putt DA; Hueni SE; Krause RJ; Elfarra AA
    J Pharmacol Exp Ther; 2003 Jun; 305(3):1163-72. PubMed ID: 12626654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interactive toxicity of inorganic mercury and trichloroethylene in rat and human proximal tubules: effects on apoptosis, necrosis, and glutathione status.
    Lash LH; Putt DA; Hueni SE; Payton SG; Zwickl J
    Toxicol Appl Pharmacol; 2007 Jun; 221(3):349-62. PubMed ID: 17481684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of cytochrome P450 and glutathione S-transferase alpha in the metabolism and cytotoxicity of trichloroethylene in rat kidney.
    Cummings BS; Parker JC; Lash LH
    Biochem Pharmacol; 2000 Mar; 59(5):531-43. PubMed ID: 10660119
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glutathione-dependent metabolism of trichloroethylene in isolated liver and kidney cells of rats and its role in mitochondrial and cellular toxicity.
    Lash LH; Xu Y; Elfarra AA; Duescher RJ; Parker JC
    Drug Metab Dispos; 1995 Aug; 23(8):846-53. PubMed ID: 7493552
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Changes in gene expression in human renal proximal tubule cells exposed to low concentrations of S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene.
    Lock EA; Barth JL; Argraves SW; Schnellmann RG
    Toxicol Appl Pharmacol; 2006 Oct; 216(2):319-30. PubMed ID: 16844155
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells.
    McGoldrick TA; Lock EA; Rodilla V; Hawksworth GM
    Arch Toxicol; 2003 Jul; 77(7):365-70. PubMed ID: 12700887
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide.
    Lash LH; Sausen PJ; Duescher RJ; Cooley AJ; Elfarra AA
    J Pharmacol Exp Ther; 1994 Apr; 269(1):374-83. PubMed ID: 8169843
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells.
    Lash LH; Anders MW
    J Biol Chem; 1986 Oct; 261(28):13076-81. PubMed ID: 2875994
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apoptosis, necrosis, and cell proliferation induced by S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells.
    Lash LH; Hueni SE; Putt DA
    Toxicol Appl Pharmacol; 2001 Nov; 177(1):1-16. PubMed ID: 11708895
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glutathione conjugation of trichloroethylene in human liver and kidney: kinetics and individual variation.
    Lash LH; Lipscomb JC; Putt DA; Parker JC
    Drug Metab Dispos; 1999 Mar; 27(3):351-9. PubMed ID: 10064565
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular markers of trichloroethylene-induced toxicity in human kidney cells.
    Lash LH; Putt DA; Hueni SE; Horwitz BP
    Toxicol Appl Pharmacol; 2005 Aug; 206(2):157-68. PubMed ID: 15967204
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione.
    Lash LH; Putt DA; Huang P; Hueni SE; Parker JC
    Toxicology; 2007 Jun; 235(1-2):11-26. PubMed ID: 17433522
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells.
    Chen JC; Stevens JL; Trifillis AL; Jones TW
    Toxicol Appl Pharmacol; 1990 May; 103(3):463-73. PubMed ID: 2339419
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-Acetyl-L-cysteine and aminooxyacetic acid differentially modulate toxicity of the trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine in human placental villous trophoblast BeWo cells.
    Su AL; Lash LH; Loch-Caruso R
    Toxicology; 2023 Aug; 495():153611. PubMed ID: 37544576
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells.
    Lash LH; Anders MW
    J Pharmacol Exp Ther; 1989 Feb; 248(2):531-7. PubMed ID: 2918469
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exposure to cis- and trans-regioisomers of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-glutathione result in quantitatively and qualitatively different cellular effects in RPTEC/TERT1 cells.
    Capinha L; Jennings P; Commandeur JNM
    Toxicol Lett; 2023 Jul; 383():75-88. PubMed ID: 37353095
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation.
    Bernauer U; Birner G; Dekant W; Henschler D
    Arch Toxicol; 1996; 70(6):338-46. PubMed ID: 8975632
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models.
    Capinha L; Zhang Y; Holzer AK; Ückert AK; Zana M; Carta G; Murphy C; Baldovini J; Mazidi Z; Grillari J; Dinnyes A; van de Water B; Leist M; Commandeur JNM; Jennings P
    Arch Toxicol; 2023 Feb; 97(2):523-545. PubMed ID: 36576512
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.