898 related articles for article (PubMed ID: 10698680)
1. The PI3K-PDK1 connection: more than just a road to PKB.
Vanhaesebroeck B; Alessi DR
Biochem J; 2000 Mar; 346 Pt 3(Pt 3):561-76. PubMed ID: 10698680
[TBL] [Abstract][Full Text] [Related]
2. PDK1 and PKB/Akt: ideal targets for development of new strategies to structure-based drug design.
Harris TK
IUBMB Life; 2003 Mar; 55(3):117-26. PubMed ID: 12822887
[TBL] [Abstract][Full Text] [Related]
3. Regulation of protein kinase B.
Meier R; Hemmings BA
J Recept Signal Transduct Res; 1999; 19(1-4):121-8. PubMed ID: 10071752
[TBL] [Abstract][Full Text] [Related]
4. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2.
Kobayashi T; Cohen P
Biochem J; 1999 Apr; 339 ( Pt 2)(Pt 2):319-28. PubMed ID: 10191262
[TBL] [Abstract][Full Text] [Related]
5. Differential activation of the phosphatidylinositol 3'-kinase/Akt survival pathway by ionizing radiation in tumor and primary endothelial cells.
Zingg D; Riesterer O; Fabbro D; Glanzmann C; Bodis S; Pruschy M
Cancer Res; 2004 Aug; 64(15):5398-406. PubMed ID: 15289348
[TBL] [Abstract][Full Text] [Related]
6. p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes.
Genot E; Reif K; Beach S; Kramer I; Cantrell D
Oncogene; 1998 Oct; 17(13):1731-8. PubMed ID: 9796702
[TBL] [Abstract][Full Text] [Related]
7. Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
Milburn CC; Deak M; Kelly SM; Price NC; Alessi DR; Van Aalten DM
Biochem J; 2003 Nov; 375(Pt 3):531-8. PubMed ID: 12964941
[TBL] [Abstract][Full Text] [Related]
8. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.
Kandel ES; Hay N
Exp Cell Res; 1999 Nov; 253(1):210-29. PubMed ID: 10579924
[TBL] [Abstract][Full Text] [Related]
9. Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes.
Yamada T; Katagiri H; Asano T; Tsuru M; Inukai K; Ono H; Kodama T; Kikuchi M; Oka Y
Am J Physiol Endocrinol Metab; 2002 Jun; 282(6):E1385-94. PubMed ID: 12006370
[TBL] [Abstract][Full Text] [Related]
10. 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.
Alessi DR; Deak M; Casamayor A; Caudwell FB; Morrice N; Norman DG; Gaffney P; Reese CB; MacDougall CN; Harbison D; Ashworth A; Bownes M
Curr Biol; 1997 Oct; 7(10):776-89. PubMed ID: 9368760
[TBL] [Abstract][Full Text] [Related]
11. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
Sekulić A; Hudson CC; Homme JL; Yin P; Otterness DM; Karnitz LM; Abraham RT
Cancer Res; 2000 Jul; 60(13):3504-13. PubMed ID: 10910062
[TBL] [Abstract][Full Text] [Related]
12. PI3K/Akt signalling pathway and cancer.
Fresno Vara JA; Casado E; de Castro J; Cejas P; Belda-Iniesta C; González-Barón M
Cancer Treat Rev; 2004 Apr; 30(2):193-204. PubMed ID: 15023437
[TBL] [Abstract][Full Text] [Related]
13. [Protein kinase B and its role in the signal transduction pathway mediated by phosphoinositide 3-kinase].
Zou W; Li ZY; Li CL; Cui ZC
Sheng Li Ke Xue Jin Zhan; 2000 Apr; 31(2):120-4. PubMed ID: 12545728
[TBL] [Abstract][Full Text] [Related]
14. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction.
Burgering BM; Coffer PJ
Nature; 1995 Aug; 376(6541):599-602. PubMed ID: 7637810
[TBL] [Abstract][Full Text] [Related]
15. Effect of overexpression and nuclear translocation of constitutively active PKB-alpha on cellular survival and proliferation in HepG2 cells.
Gupta D; Syed NA; Roesler WJ; Khandelwal RL
J Cell Biochem; 2004 Oct; 93(3):513-25. PubMed ID: 15372623
[TBL] [Abstract][Full Text] [Related]
16. Sustained Akt/PKB activation and transient attenuation of c-jun N-terminal kinase in the inhibition of apoptosis by IGF-1 in vascular smooth muscle cells.
Allen RT; Krueger KD; Dhume A; Agrawal DK
Apoptosis; 2005 May; 10(3):525-35. PubMed ID: 15909115
[TBL] [Abstract][Full Text] [Related]
17. Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.
Currie RA; Walker KS; Gray A; Deak M; Casamayor A; Downes CP; Cohen P; Alessi DR; Lucocq J
Biochem J; 1999 Feb; 337 ( Pt 3)(Pt 3):575-83. PubMed ID: 9895304
[TBL] [Abstract][Full Text] [Related]
18. Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor.
Dijkers PF; van Dijk TB; de Groot RP; Raaijmakers JA; Lammers JW; Koenderman L; Coffer PJ
Oncogene; 1999 Jun; 18(22):3334-42. PubMed ID: 10362354
[TBL] [Abstract][Full Text] [Related]
19. Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1.
Wick MJ; Dong LQ; Riojas RA; Ramos FJ; Liu F
J Biol Chem; 2000 Dec; 275(51):40400-6. PubMed ID: 11006271
[TBL] [Abstract][Full Text] [Related]
20. The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.
Biondi RM; Kieloch A; Currie RA; Deak M; Alessi DR
EMBO J; 2001 Aug; 20(16):4380-90. PubMed ID: 11500365
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
