211 related articles for article (PubMed ID: 10699948)
1. Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis.
Gajate C; Fonteriz RI; Cabaner C; Alvarez-Noves G; Alvarez-Rodriguez Y; Modolell M; Mollinedo F
Int J Cancer; 2000 Mar; 85(5):674-82. PubMed ID: 10699948
[TBL] [Abstract][Full Text] [Related]
2. Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis.
Gajate C; Del Canto-Jañez E; Acuña AU; Amat-Guerri F; Geijo E; Santos-Beneit AM; Veldman RJ; Mollinedo F
J Exp Med; 2004 Aug; 200(3):353-65. PubMed ID: 15289504
[TBL] [Abstract][Full Text] [Related]
3. Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system.
Cabaner C; Gajate C; Macho A; Muñoz E; Modolell M; Mollinedo F
Br J Pharmacol; 1999 Jun; 127(4):813-25. PubMed ID: 10433487
[TBL] [Abstract][Full Text] [Related]
4. The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells.
Gajate C; Mollinedo F
Blood; 2001 Dec; 98(13):3860-3. PubMed ID: 11739199
[TBL] [Abstract][Full Text] [Related]
5. Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells.
Gajate C; Santos-Beneit AM; Macho A; Lazaro Md; Hernandez-De Rojas A; Modolell M; Muñoz E; Mollinedo F
Int J Cancer; 2000 Apr; 86(2):208-18. PubMed ID: 10738248
[TBL] [Abstract][Full Text] [Related]
6. Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH(3) (edelfosine), a proapoptotic agent in tumor cells.
Gajate C; Mollinedo F
Curr Drug Metab; 2002 Oct; 3(5):491-525. PubMed ID: 12369895
[TBL] [Abstract][Full Text] [Related]
7. ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor.
Mollinedo F; Gajate C; Martín-Santamaría S; Gago F
Curr Med Chem; 2004 Dec; 11(24):3163-84. PubMed ID: 15579006
[TBL] [Abstract][Full Text] [Related]
8. Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (Edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L).
Mollinedo F; Fernández-Luna JL; Gajate C; Martín-Martín B; Benito A; Martínez-Dalmau R; Modolell M
Cancer Res; 1997 Apr; 57(7):1320-8. PubMed ID: 9102220
[TBL] [Abstract][Full Text] [Related]
9. Liposomal ET-18-OCH(3) induces cytochrome c-mediated apoptosis independently of CD95 (APO-1/Fas) signaling.
Cuvillier O; Mayhew E; Janoff AS; Spiegel S
Blood; 1999 Nov; 94(10):3583-92. PubMed ID: 10552970
[TBL] [Abstract][Full Text] [Related]
10. Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy.
Gajate C; Mollinedo F
J Biol Chem; 2005 Mar; 280(12):11641-7. PubMed ID: 15659383
[TBL] [Abstract][Full Text] [Related]
11. Bcl-2 inhibits calcineurin-mediated Fas ligand expression in antitumor drug-treated baby hamster kidney cells.
Simizu S; Shibasaki F; Osada H
Jpn J Cancer Res; 2000 Jul; 91(7):706-14. PubMed ID: 10920278
[TBL] [Abstract][Full Text] [Related]
12. Drug-induced apoptosis in lung cnacer cells is not mediated by the Fas/FasL (CD95/APO1) signaling pathway.
Ferreira CG; Tolis C; Span SW; Peters GJ; van Lopik T; Kummer AJ; Pinedo HM; Giaccone G
Clin Cancer Res; 2000 Jan; 6(1):203-12. PubMed ID: 10656451
[TBL] [Abstract][Full Text] [Related]
13. Involvement of c-Jun NH2-terminal kinase activation and c-Jun in the induction of apoptosis by the ether phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine.
Gajate C; Santos-Beneit A; Modolell M; Mollinedo F
Mol Pharmacol; 1998 Apr; 53(4):602-12. PubMed ID: 9547349
[TBL] [Abstract][Full Text] [Related]
14. Fas receptor (CD95)-mediated apoptosis in leukemic cells.
Komada Y; Sakurai M
Leuk Lymphoma; 1997 Mar; 25(1-2):9-21. PubMed ID: 9130610
[TBL] [Abstract][Full Text] [Related]
15. Activity, pharmacokinetics and tissue distribution of TLC ELL-12 (liposomal antitumor ether lipid) in rats with transplantable, s.c. methylnitrosourea-induced tumors.
Bhamra R; Bolcsak LE; Ahmad I; Schupsky J; Roberts P; Stevens R; Cavanaugh C; Swenson CE
Anticancer Drugs; 2003 Jul; 14(6):481-6. PubMed ID: 12853892
[TBL] [Abstract][Full Text] [Related]
16. In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts.
Mollinedo F; de la Iglesia-Vicente J; Gajate C; Estella-Hermoso de Mendoza A; Villa-Pulgarin JA; de Frias M; Roué G; Gil J; Colomer D; Campanero MA; Blanco-Prieto MJ
Clin Cancer Res; 2010 Apr; 16(7):2046-54. PubMed ID: 20233887
[TBL] [Abstract][Full Text] [Related]
17. Blockade of the Fas-triggered intracellular signaling pathway in human melanomas is circumvented by cytotoxic lymphocytes.
Ferrarini M; Imro MA; Sciorati C; Heltai S; Protti MP; Pellicciari C; Rovere P; Manfredi AA; Rugarli C
Int J Cancer; 1999 May; 81(4):573-9. PubMed ID: 10225447
[TBL] [Abstract][Full Text] [Related]
18. Cryptosporidium parvum induces apoptosis in biliary epithelia by a Fas/Fas ligand-dependent mechanism.
Chen XM; Gores GJ; Paya CV; LaRusso NF
Am J Physiol; 1999 Sep; 277(3):G599-608. PubMed ID: 10484385
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of FAS/FAS-ligand does not block chemotherapy-induced apoptosis in drug sensitive and resistant cells.
Richardson DS; Allen PD; Kelsey SM; Newland AC
Adv Exp Med Biol; 1999; 457():259-66. PubMed ID: 10500801
[TBL] [Abstract][Full Text] [Related]
20. Mature but not immature Fas ligand (CD95L)-transduced human monocyte-derived dendritic cells are protected from Fas-mediated apoptosis and can be used as killer APC.
Hoves S; Krause SW; Halbritter D; Zhang HG; Mountz JD; Schölmerich J; Fleck M
J Immunol; 2003 Jun; 170(11):5406-13. PubMed ID: 12759415
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]