BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 10702222)

  • 1. Unique in vivo associations with SmgGDS and RhoGDI and different guanine nucleotide exchange activities exhibited by RhoA, dominant negative RhoA(Asn-19), and activated RhoA(Val-14).
    Strassheim D; Porter RA; Phelps SH; Williams CL
    J Biol Chem; 2000 Mar; 275(10):6699-702. PubMed ID: 10702222
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human RhoA/RhoGDI complex expressed in yeast: GTP exchange is sufficient for translocation of RhoA to liposomes.
    Read PW; Liu X; Longenecker K; Dipierro CG; Walker LA; Somlyo AV; Somlyo AP; Nakamoto RK
    Protein Sci; 2000 Feb; 9(2):376-86. PubMed ID: 10716190
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG.
    Zalcman G; Closson V; Camonis J; Honoré N; Rousseau-Merck MF; Tavitian A; Olofsson B
    J Biol Chem; 1996 Nov; 271(48):30366-74. PubMed ID: 8939998
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SmgGDS-607 Regulation of RhoA GTPase Prenylation Is Nucleotide-Dependent.
    Jennings BC; Lawton AJ; Rizk Z; Fierke CA
    Biochemistry; 2018 Jul; 57(29):4289-4298. PubMed ID: 29940100
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC.
    Hamel B; Monaghan-Benson E; Rojas RJ; Temple BR; Marston DJ; Burridge K; Sondek J
    J Biol Chem; 2011 Apr; 286(14):12141-8. PubMed ID: 21242305
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP.
    Ugolev Y; Berdichevsky Y; Weinbaum C; Pick E
    J Biol Chem; 2008 Aug; 283(32):22257-71. PubMed ID: 18505730
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases.
    Bergom C; Hauser AD; Rymaszewski A; Gonyo P; Prokop JW; Jennings BC; Lawton AJ; Frei A; Lorimer EL; Aguilera-Barrantes I; Mackinnon AC; Noon K; Fierke CA; Williams CL
    J Biol Chem; 2016 Mar; 291(12):6534-45. PubMed ID: 26814130
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Splice variants of SmgGDS control small GTPase prenylation and membrane localization.
    Berg TJ; Gastonguay AJ; Lorimer EL; Kuhnmuench JR; Li R; Fields AP; Williams CL
    J Biol Chem; 2010 Nov; 285(46):35255-66. PubMed ID: 20709748
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors.
    Turner SJ; Zhuang S; Zhang T; Boss GR; Pilz RB
    Biochem Pharmacol; 2008 Jan; 75(2):405-13. PubMed ID: 17920041
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI.
    Golovanov AP; Chuang TH; DerMardirossian C; Barsukov I; Hawkins D; Badii R; Bokoch GM; Lian LY; Roberts GC
    J Mol Biol; 2001 Jan; 305(1):121-35. PubMed ID: 11114252
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quantitative analysis of prenylated RhoA interaction with its chaperone, RhoGDI.
    Tnimov Z; Guo Z; Gambin Y; Nguyen UT; Wu YW; Abankwa D; Stigter A; Collins BM; Waldmann H; Goody RS; Alexandrov K
    J Biol Chem; 2012 Aug; 287(32):26549-62. PubMed ID: 22628549
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins.
    Zhang B; Zhang Y; Wang Z; Zheng Y
    J Biol Chem; 2000 Aug; 275(33):25299-307. PubMed ID: 10843989
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF.
    Gasmi-Seabrook GM; Marshall CB; Cheung M; Kim B; Wang F; Jang YJ; Mak TW; Stambolic V; Ikura M
    J Biol Chem; 2010 Feb; 285(8):5137-45. PubMed ID: 20018869
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding.
    Shimizu H; Toma-Fukai S; Saijo S; Shimizu N; Kontani K; Katada T; Shimizu T
    J Biol Chem; 2017 Aug; 292(32):13441-13448. PubMed ID: 28630045
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Disruption of RhoGDI and RhoA regulation by a Rac1 specificity switch mutant.
    Wong KW; Mohammadi S; Isberg RR
    J Biol Chem; 2006 Dec; 281(52):40379-88. PubMed ID: 17074770
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SmgGDS displays differential binding and exchange activity towards different Ras isoforms.
    Vikis HG; Stewart S; Guan KL
    Oncogene; 2002 Apr; 21(15):2425-32. PubMed ID: 11948427
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Serine phosphorylation negatively regulates RhoA in vivo.
    Ellerbroek SM; Wennerberg K; Burridge K
    J Biol Chem; 2003 May; 278(21):19023-31. PubMed ID: 12654918
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of morphology by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in Swiss 3T3 cells.
    Miura Y; Kikuchi A; Musha T; Kuroda S; Yaku H; Sasaki T; Takai Y
    J Biol Chem; 1993 Jan; 268(1):510-5. PubMed ID: 8416955
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel role for RhoGDI as an inhibitor of GAP proteins.
    Hancock JF; Hall A
    EMBO J; 1993 May; 12(5):1915-21. PubMed ID: 8491184
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular mechanism of regulation of RhoA GTPase by phosphorylation of RhoGDI.
    Sinha K; Kumawat A; Jang H; Nussinov R; Chakrabarty S
    Biophys J; 2024 Jan; 123(1):57-67. PubMed ID: 37978802
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.