BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 10702394)

  • 1. KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors.
    Lux ML; Rubin BP; Biase TL; Chen CJ; Maclure T; Demetri G; Xiao S; Singer S; Fletcher CD; Fletcher JA
    Am J Pathol; 2000 Mar; 156(3):791-5. PubMed ID: 10702394
    [TBL] [Abstract][Full Text] [Related]  

  • 2. KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.
    Rubin BP; Singer S; Tsao C; Duensing A; Lux ML; Ruiz R; Hibbard MK; Chen CJ; Xiao S; Tuveson DA; Demetri GD; Fletcher CD; Fletcher JA
    Cancer Res; 2001 Nov; 61(22):8118-21. PubMed ID: 11719439
    [TBL] [Abstract][Full Text] [Related]  

  • 3. c-kit mutations in gastrointestinal stromal tumors occur preferentially in the spindle rather than in the epithelioid cell variant.
    Wardelmann E; Neidt I; Bierhoff E; Speidel N; Manegold C; Fischer HP; Pfeifer U; Pietsch T
    Mod Pathol; 2002 Feb; 15(2):125-36. PubMed ID: 11850541
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gastrointestinal stromal tumors with internal tandem duplications in 3' end of KIT juxtamembrane domain occur predominantly in stomach and generally seem to have a favorable course.
    Lasota J; Dansonka-Mieszkowska A; Stachura T; Schneider-Stock R; Kallajoki M; Steigen SE; Sarlomo-Rikala M; Boltze C; Kordek R; Roessner A; Stachura J; Miettinen M
    Mod Pathol; 2003 Dec; 16(12):1257-64. PubMed ID: 14681327
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours.
    Hirota S; Nishida T; Isozaki K; Taniguchi M; Nakamura J; Okazaki T; Kitamura Y
    J Pathol; 2001 Apr; 193(4):505-10. PubMed ID: 11276010
    [TBL] [Abstract][Full Text] [Related]  

  • 6. KIT gene deletions at the intron 10-exon 11 boundary in GI stromal tumors.
    Corless CL; McGreevey L; Town A; Schroeder A; Bainbridge T; Harrell P; Fletcher JA; Heinrich MC
    J Mol Diagn; 2004 Nov; 6(4):366-70. PubMed ID: 15507676
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity.
    Debiec-Rychter M; Wasag B; Stul M; De Wever I; Van Oosterom A; Hagemeijer A; Sciot R
    J Pathol; 2004 Apr; 202(4):430-8. PubMed ID: 15095270
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Absence of c-kit gene mutations in gastrointestinal stromal tumours from neurofibromatosis type 1 patients.
    Kinoshita K; Hirota S; Isozaki K; Ohashi A; Nishida T; Kitamura Y; Shinomura Y; Matsuzawa Y
    J Pathol; 2004 Jan; 202(1):80-5. PubMed ID: 14694524
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors.
    Moskaluk CA; Tian Q; Marshall CR; Rumpel CA; Franquemont DW; Frierson HF
    Oncogene; 1999 Mar; 18(10):1897-902. PubMed ID: 10086344
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors.
    Taniguchi M; Nishida T; Hirota S; Isozaki K; Ito T; Nomura T; Matsuda H; Kitamura Y
    Cancer Res; 1999 Sep; 59(17):4297-300. PubMed ID: 10485475
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Detection of c-kit-activating mutations in gastrointestinal stromal tumors by high-resolution amplicon melting analysis.
    Willmore C; Holden JA; Zhou L; Tripp S; Wittwer CT; Layfield LJ
    Am J Clin Pathol; 2004 Aug; 122(2):206-16. PubMed ID: 15323137
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors.
    Wardelmann E; Losen I; Hans V; Neidt I; Speidel N; Bierhoff E; Heinicke T; Pietsch T; Büttner R; Merkelbach-Bruse S
    Int J Cancer; 2003 Oct; 106(6):887-95. PubMed ID: 12918066
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors.
    Chen LL; Trent JC; Wu EF; Fuller GN; Ramdas L; Zhang W; Raymond AK; Prieto VG; Oyedeji CO; Hunt KK; Pollock RE; Feig BW; Hayes KJ; Choi H; Macapinlac HA; Hittelman W; Velasco MA; Patel S; Burgess MA; Benjamin RS; Frazier ML
    Cancer Res; 2004 Sep; 64(17):5913-9. PubMed ID: 15342366
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach.
    Cho S; Kitadai Y; Yoshida S; Tanaka S; Yoshihara M; Yoshida K; Chayama K
    Int J Oncol; 2006 Jun; 28(6):1361-7. PubMed ID: 16685437
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gastrointestinal stromal tumors (GISTs): definition, occurrence, pathology, differential diagnosis and molecular genetics.
    Miettinen M; Lasota J
    Pol J Pathol; 2003; 54(1):3-24. PubMed ID: 12817876
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in exon 11 of the c-kit gene in a myogenic tumor and a neurogenic tumor as well as in gastrointestinal stromal tumors. Utility of c-kit mutation as a prognostic biomarker for gastrointestinal mesenchymal tumor.
    Yasuoka R; Sakakura C; Shimomura K; Fujita Y; Nakanishi M; Aragane H; Hagiwara A; Bamba M; Abe T; Yamagishi H
    Dig Surg; 2003; 20(3):183-91. PubMed ID: 12759497
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs).
    Duensing A; Medeiros F; McConarty B; Joseph NE; Panigrahy D; Singer S; Fletcher CD; Demetri GD; Fletcher JA
    Oncogene; 2004 May; 23(22):3999-4006. PubMed ID: 15007386
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors.
    Singer S; Rubin BP; Lux ML; Chen CJ; Demetri GD; Fletcher CD; Fletcher JA
    J Clin Oncol; 2002 Sep; 20(18):3898-905. PubMed ID: 12228211
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases.
    Lasota J; Wozniak A; Sarlomo-Rikala M; Rys J; Kordek R; Nassar A; Sobin LH; Miettinen M
    Am J Pathol; 2000 Oct; 157(4):1091-5. PubMed ID: 11021812
    [TBL] [Abstract][Full Text] [Related]  

  • 20. KIT exon 11 deletion-inversions represent complex mutations in gastrointestinal stromal tumors.
    Lasota J; Miettinen M
    Cancer Genet Cytogenet; 2007 May; 175(1):69-72. PubMed ID: 17498562
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.