BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 10713097)

  • 1. Characterization of glucokinase regulatory protein-deficient mice.
    Grimsby J; Coffey JW; Dvorozniak MT; Magram J; Li G; Matschinsky FM; Shiota C; Kaur S; Magnuson MA; Grippo JF
    J Biol Chem; 2000 Mar; 275(11):7826-31. PubMed ID: 10713097
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin-receptor substrate-2 (irs-2) is required for maintaining glucokinase and glucokinase regulatory protein expression in mouse liver.
    Roncero I; Alvarez E; Acosta C; Sanz C; Barrio P; Hurtado-Carneiro V; Burks D; Blázquez E
    PLoS One; 2013; 8(4):e58797. PubMed ID: 23560040
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Treatment of type 2 diabetes by adenoviral-mediated overexpression of the glucokinase regulatory protein.
    Slosberg ED; Desai UJ; Fanelli B; St Denny I; Connelly S; Kaleko M; Boettcher BR; Caplan SL
    Diabetes; 2001 Aug; 50(8):1813-20. PubMed ID: 11473043
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of the regulatory protein of glucokinase in the glucose sensory mechanism of the hepatocyte.
    de la Iglesia N; Mukhtar M; Seoane J; Guinovart JJ; Agius L
    J Biol Chem; 2000 Apr; 275(14):10597-603. PubMed ID: 10744755
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.
    Farrelly D; Brown KS; Tieman A; Ren J; Lira SA; Hagan D; Gregg R; Mookhtiar KA; Hariharan N
    Proc Natl Acad Sci U S A; 1999 Dec; 96(25):14511-6. PubMed ID: 10588736
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.
    Futamura M; Hosaka H; Kadotani A; Shimazaki H; Sasaki K; Ohyama S; Nishimura T; Eiki J; Nagata Y
    J Biol Chem; 2006 Dec; 281(49):37668-74. PubMed ID: 17028192
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity.
    Park JM; Kim TH; Jo SH; Kim MY; Ahn YH
    Sci Rep; 2015 Dec; 5():17395. PubMed ID: 26620281
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver.
    Beer NL; Tribble ND; McCulloch LJ; Roos C; Johnson PR; Orho-Melander M; Gloyn AL
    Hum Mol Genet; 2009 Nov; 18(21):4081-8. PubMed ID: 19643913
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse-a model for GCKR rs1260326.
    Ford BE; Chachra SS; Rodgers K; Moonira T; Al-Oanzi ZH; Anstee QM; Reeves HL; Schattenberg JM; Fairclough RJ; Smith DM; Tiniakos D; Agius L
    Mol Metab; 2023 Jun; 72():101722. PubMed ID: 37031802
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk.
    Rees MG; Wincovitch S; Schultz J; Waterstradt R; Beer NL; Baltrusch S; Collins FS; Gloyn AL
    Diabetologia; 2012 Jan; 55(1):114-22. PubMed ID: 22038520
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lack of glucokinase regulatory protein expression may contribute to low glucokinase activity in feline liver.
    Hiskett EK; Suwitheechon OU; Lindbloom-Hawley S; Boyle DL; Schermerhorn T
    Vet Res Commun; 2009 Mar; 33(3):227-40. PubMed ID: 18780155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase.
    de la Iglesia N; Veiga-da-Cunha M; Van Schaftingen E; Guinovart JJ; Ferrer JC
    FEBS Lett; 1999 Aug; 456(2):332-8. PubMed ID: 10456334
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antidiabetic Disruptors of the Glucokinase-Glucokinase Regulatory Protein Complex Reorganize a Coulombic Interface.
    Martinez JA; Xiao Q; Zakarian A; Miller BG
    Biochemistry; 2017 Jun; 56(24):3150-3157. PubMed ID: 28516783
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase.
    Choi JM; Seo MH; Kyeong HH; Kim E; Kim HS
    Proc Natl Acad Sci U S A; 2013 Jun; 110(25):10171-6. PubMed ID: 23733961
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hormonal and Metabolite Regulation of Hepatic Glucokinase.
    Agius L
    Annu Rev Nutr; 2016 Jul; 36():389-415. PubMed ID: 27146014
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of high-fat diet on glucose homeostasis and gene expression in glucokinase knockout mice.
    Gorman T; Hope DC; Brownlie R; Yu A; Gill D; Löfvenmark J; Wedin M; Mayers RM; Snaith MR; Smith DM
    Diabetes Obes Metab; 2008 Sep; 10(10):885-97. PubMed ID: 18034843
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes.
    Paliwal A; Paliwal V; Jain S; Paliwal S; Sharma S
    Mini Rev Med Chem; 2024; 24(7):674-688. PubMed ID: 37612862
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Allosteric activators of glucokinase: potential role in diabetes therapy.
    Grimsby J; Sarabu R; Corbett WL; Haynes NE; Bizzarro FT; Coffey JW; Guertin KR; Hilliard DW; Kester RF; Mahaney PE; Marcus L; Qi L; Spence CL; Tengi J; Magnuson MA; Chu CA; Dvorozniak MT; Matschinsky FM; Grippo JF
    Science; 2003 Jul; 301(5631):370-3. PubMed ID: 12869762
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators.
    Brocklehurst KJ; Payne VA; Davies RA; Carroll D; Vertigan HL; Wightman HJ; Aiston S; Waddell ID; Leighton B; Coghlan MP; Agius L
    Diabetes; 2004 Mar; 53(3):535-41. PubMed ID: 14988235
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucokinase regulatory protein: complexity at the crossroads of triglyceride and glucose metabolism.
    Raimondo A; Rees MG; Gloyn AL
    Curr Opin Lipidol; 2015 Apr; 26(2):88-95. PubMed ID: 25692341
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.