234 related articles for article (PubMed ID: 10715209)
1. Thioesterase domain of delta-(l-alpha-Aminoadipyl)-l-cysteinyl-d-valine synthetase: alteration of stereospecificity by site-directed mutagenesis.
Kallow W; Kennedy J; Arezi B; Turner G; von Döhren H
J Mol Biol; 2000 Mar; 297(2):395-408. PubMed ID: 10715209
[TBL] [Abstract][Full Text] [Related]
2. Motifs in the C-terminal region of the Penicillium chrysogenum ACV synthetase are essential for valine epimerization and processivity of tripeptide formation.
Wu X; García-Estrada C; Vaca I; Martín JF
Biochimie; 2012 Feb; 94(2):354-64. PubMed ID: 21889568
[TBL] [Abstract][Full Text] [Related]
3. Penicillin biosynthesis: energy requirement for tripeptide precursor formation by delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Acremonium chrysogenum.
Kallow W; von Döhren H; Kleinkauf H
Biochemistry; 1998 Apr; 37(17):5947-52. PubMed ID: 9558329
[TBL] [Abstract][Full Text] [Related]
4. Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans. Molecular characterization of the acvA gene encoding the first enzyme of the penicillin biosynthetic pathway.
MacCabe AP; van Liempt H; Palissa H; Unkles SE; Riach MB; Pfeifer E; von Döhren H; Kinghorn JR
J Biol Chem; 1991 Jul; 266(19):12646-54. PubMed ID: 2061333
[TBL] [Abstract][Full Text] [Related]
5. Alpha-aminoadipyl-cysteinyl-valine synthetases in beta-lactam producing organisms. From Abraham's discoveries to novel concepts of non-ribosomal peptide synthesis.
Martin JF
J Antibiot (Tokyo); 2000 Oct; 53(10):1008-21. PubMed ID: 11132945
[TBL] [Abstract][Full Text] [Related]
6. delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase is a rate limiting enzyme for penicillin production in Aspergillus nidulans.
Kennedy J; Turner G
Mol Gen Genet; 1996 Nov; 253(1-2):189-97. PubMed ID: 9003303
[TBL] [Abstract][Full Text] [Related]
7. delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans. The first enzyme in penicillin biosynthesis is a multifunctional peptide synthetase.
van Liempt H; von Döhren H; Kleinkauf H
J Biol Chem; 1989 Mar; 264(7):3680-4. PubMed ID: 2645274
[TBL] [Abstract][Full Text] [Related]
8. Conversion of serine-114 to cysteine-114 and the role of the active site nucleophile in acyl transfer by myristoyl-ACP thioesterase from Vibrio harveyi.
Li J; Szittner R; Derewenda ZS; Meighen EA
Biochemistry; 1996 Aug; 35(31):9967-73. PubMed ID: 8756458
[TBL] [Abstract][Full Text] [Related]
9. Effect of modification of the length and flexibility of the acyl carrier protein-thioesterase interdomain linker on functionality of the animal fatty acid synthase.
Joshi AK; Witkowski A; Berman HA; Zhang L; Smith S
Biochemistry; 2005 Mar; 44(10):4100-7. PubMed ID: 15751987
[TBL] [Abstract][Full Text] [Related]
10. Penicillin biosynthesis: intermediates of biosynthesis of delta-L-alpha-aminoadipyl-L-cysteinyl-D-valine formed by ACV synthetase from Acremonium chrysogenum.
Kallow W; Neuhof T; Arezi B; Jungblut P; von Döhren H
FEBS Lett; 1997 Sep; 414(1):74-8. PubMed ID: 9305735
[TBL] [Abstract][Full Text] [Related]
11. L-delta-(alpha-Aminoadipoyl)-L-cysteinyl-D-valine synthetase: thioesterification of valine is not obligatory for peptide bond formation.
Shiau CY; Byford MF; Aplin RT; Baldwin JE; Schofield CJ
Biochemistry; 1997 Jul; 36(29):8798-806. PubMed ID: 9220966
[TBL] [Abstract][Full Text] [Related]
12. Nonribosomal peptide synthetases-evidence for a second ATP-binding site.
Kallow W; Pavela-Vrancic M; Dieckmann R; von Döhren H
Biochim Biophys Acta; 2002 Nov; 1601(1):93-9. PubMed ID: 12429507
[TBL] [Abstract][Full Text] [Related]
13. Mutational analysis of a type II thioesterase associated with nonribosomal peptide synthesis.
Linne U; Schwarzer D; Schroeder GN; Marahiel MA
Eur J Biochem; 2004 Apr; 271(8):1536-45. PubMed ID: 15066179
[TBL] [Abstract][Full Text] [Related]
14. In vivo characterization of tandem C-terminal thioesterase domains in arthrofactin synthetase.
Roongsawang N; Washio K; Morikawa M
Chembiochem; 2007 Mar; 8(5):501-12. PubMed ID: 17328008
[TBL] [Abstract][Full Text] [Related]
15. Utility of epimerization domains for the redesign of nonribosomal peptide synthetases.
Stein DB; Linne U; Marahiel MA
FEBS J; 2005 Sep; 272(17):4506-20. PubMed ID: 16128819
[TBL] [Abstract][Full Text] [Related]
16. Crystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthase.
Ge W; Clifton IJ; Stok JE; Adlington RM; Baldwin JE; Rutledge PJ
Biochem Biophys Res Commun; 2010 Aug; 398(4):659-64. PubMed ID: 20603104
[TBL] [Abstract][Full Text] [Related]
17. Characterization of the Cephalosporium acremonium pcbAB gene encoding alpha-aminoadipyl-cysteinyl-valine synthetase, a large multidomain peptide synthetase: linkage to the pcbC gene as a cluster of early cephalosporin biosynthetic genes and evidence of multiple functional domains.
Gutiérrez S; Díez B; Montenegro E; Martín JF
J Bacteriol; 1991 Apr; 173(7):2354-65. PubMed ID: 1706706
[TBL] [Abstract][Full Text] [Related]
18. Chirality of peptide bond-forming condensation domains in nonribosomal peptide synthetases: the C5 domain of tyrocidine synthetase is a (D)C(L) catalyst.
Clugston SL; Sieber SA; Marahiel MA; Walsh CT
Biochemistry; 2003 Oct; 42(41):12095-104. PubMed ID: 14556641
[TBL] [Abstract][Full Text] [Related]
19. The thioesterase domain of the fengycin biosynthesis cluster: a structural base for the macrocyclization of a non-ribosomal lipopeptide.
Samel SA; Wagner B; Marahiel MA; Essen LO
J Mol Biol; 2006 Jun; 359(4):876-89. PubMed ID: 16697411
[TBL] [Abstract][Full Text] [Related]
20. delta-(L-alpha-Aminoadipyl)-L-cysteinyl-D-valine synthetase, that mediates the first committed step in penicillin biosynthesis, is a cytosolic enzyme.
van der Lende TR; van de Kamp M; Berg M; Sjollema K; Bovenberg RA; Veenhuis M; Konings WN; Driessen AJ
Fungal Genet Biol; 2002 Oct; 37(1):49-55. PubMed ID: 12223189
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]