BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 10720751)

  • 1. N-Acetyltransferase genetics and their role in predisposition to aromatic and heterocyclic amine-induced carcinogenesis.
    Hein DW
    Toxicol Lett; 2000 Mar; 112-113():349-56. PubMed ID: 10720751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis.
    Hein DW
    Mutat Res; 2002 Sep; 506-507():65-77. PubMed ID: 12351146
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.
    Hein DW; Doll MA; Fretland AJ; Leff MA; Webb SJ; Xiao GH; Devanaboyina US; Nangju NA; Feng Y
    Cancer Epidemiol Biomarkers Prev; 2000 Jan; 9(1):29-42. PubMed ID: 10667461
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
    Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ
    Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.
    Jefferson FA; Xiao GH; Hein DW
    Toxicol Sci; 2009 Jan; 107(1):293-7. PubMed ID: 18842621
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.
    Hein DW; Doll MA; Rustan TD; Gray K; Feng Y; Ferguson RJ; Grant DM
    Carcinogenesis; 1993 Aug; 14(8):1633-8. PubMed ID: 8353847
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of nucleotide substitutions in N-acetyltransferase-1 on N-acetylation (deactivation) and O-acetylation (activation) of arylamine carcinogens: implications for cancer predisposition.
    Fretland AJ; Doll MA; Zhu Y; Smith L; Leff MA; Hein DW
    Cancer Detect Prev; 2002; 26(1):10-4. PubMed ID: 12088197
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rodent models of the human acetylation polymorphism: comparisons of recombinant acetyltransferases.
    Hein DW; Doll MA; Fretland AJ; Gray K; Deitz AC; Feng Y; Jiang W; Rustan TD; Satran SL; Wilkie TR
    Mutat Res; 1997 May; 376(1-2):101-6. PubMed ID: 9202744
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens.
    Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW
    Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-Acetyltransferase-2 genetic polymorphism, well-done meat intake, and breast cancer risk among postmenopausal women.
    Deitz AC; Zheng W; Leff MA; Gross M; Wen WQ; Doll MA; Xiao GH; Folsom AR; Hein DW
    Cancer Epidemiol Biomarkers Prev; 2000 Sep; 9(9):905-10. PubMed ID: 11008907
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption.
    Lilla C; Verla-Tebit E; Risch A; Jäger B; Hoffmeister M; Brenner H; Chang-Claude J
    Cancer Epidemiol Biomarkers Prev; 2006 Jan; 15(1):99-107. PubMed ID: 16434594
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1.
    Fretland AJ; Doll MA; Leff MA; Hein DW
    Pharmacogenetics; 2001 Aug; 11(6):511-20. PubMed ID: 11505221
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens.
    Hein DW; Doll MA; Rustan TD; Gray K; Ferguson RJ; Feng Y
    Toxicol Appl Pharmacol; 1994 Jan; 124(1):16-24. PubMed ID: 8291057
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) polymorphisms in susceptibility to bladder cancer: the influence of smoking.
    Okkels H; Sigsgaard T; Wolf H; Autrup H
    Cancer Epidemiol Biomarkers Prev; 1997 Apr; 6(4):225-31. PubMed ID: 9107426
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A pilot study investigating the role of NAT1 and NAT2 polymorphisms in gastric adenocarcinoma.
    Boissy RJ; Watson MA; Umbach DM; Deakin M; Elder J; Strange RC; Bell DA
    Int J Cancer; 2000 Aug; 87(4):507-11. PubMed ID: 10918189
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-acetyltransferase (NAT1, NAT2) and glutathione S-transferase (GSTM1, GSTT1) polymorphisms in breast cancer.
    Lee KM; Park SK; Kim SU; Doll MA; Yoo KY; Ahn SH; Noh DY; Hirvonen A; Hein DW; Kang D
    Cancer Lett; 2003 Jul; 196(2):179-86. PubMed ID: 12860276
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inherited polymorphism in the N-acetyltransferase 1 (NAT1) and 2 (NAT2) genes and susceptibility to gastric and colorectal adenocarcinoma.
    Katoh T; Boissy R; Nagata N; Kitagawa K; Kuroda Y; Itoh H; Kawamoto T; Bell DA
    Int J Cancer; 2000 Jan; 85(1):46-9. PubMed ID: 10585581
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic activation of aromatic and heterocyclic N-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases.
    Hein DW; Rustan TD; Ferguson RJ; Doll MA; Gray K
    Arch Toxicol; 1994; 68(2):129-33. PubMed ID: 8179482
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes.
    Grant DM; Blum M; Beer M; Meyer UA
    Mol Pharmacol; 1991 Feb; 39(2):184-91. PubMed ID: 1996083
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk.
    Hein DW
    Oncogene; 2006 Mar; 25(11):1649-58. PubMed ID: 16550165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.