BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 10722161)

  • 1. Synthesis and antitumor activity of duocarmycin derivatives: modification at C-8 position of A-ring pyrrole compounds bearing the simplified DNA-binding groups.
    Amishiro N; Nagamura S; Murakata C; Okamoto A; Kobayashi E; Asada M; Gomi K; Tamaoki T; Okabe M; Yamaguchi N; Yamaguchi K; Saito H
    Bioorg Med Chem; 2000 Feb; 8(2):381-91. PubMed ID: 10722161
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and antitumor activity of duocarmycin derivatives: a-ring pyrrole compounds bearing 5-membered heteroarylacryloyl groups.
    Amishiro N; Nagamura S; Kobayashi E; Okamoto A; Gomi K; Saito H
    Chem Pharm Bull (Tokyo); 1999 Oct; 47(10):1393-403. PubMed ID: 10553637
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New water-soluble duocarmycin derivatives: synthesis and antitumor activity of A-ring pyrrole compounds bearing beta-heteroarylacryloyl groups.
    Amishiro N; Nagamura S; Kobayashi E; Gomi K; Saito H
    J Med Chem; 1999 Feb; 42(4):669-76. PubMed ID: 10052974
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing cinnamoyl groups.
    Nagamura S; Asai A; Amishiro N; Kobayashi E; Gomi K; Saito H
    J Med Chem; 1997 Mar; 40(6):972-9. PubMed ID: 9083487
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and antitumor activity of duocarmycin derivatives: modification at the C-7 position of segment-A of A-ring pyrrole compounds.
    Amishiro N; Okamoto A; Okabe M; Saito H
    Bioorg Med Chem; 2000 May; 8(5):1195-201. PubMed ID: 10882029
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole analogues of duocarmycin B2.
    Nagamura S; Kobayashi E; Gomi K; Saito H
    Bioorg Med Chem; 1996 Aug; 4(8):1379-91. PubMed ID: 8879561
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing beta-(5',6',7'-trimethoxy-2'-indolyl)acryloyl group.
    Amishiro N; Nagamura S; Kobayashi E; Okamoto A; Gomi K; Okabe M; Saito H
    Bioorg Med Chem; 2000 Jul; 8(7):1637-43. PubMed ID: 10976511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds.
    Amishiro N; Okamoto A; Murakata C; Tamaoki T; Okabe M; Saito H
    J Med Chem; 1999 Jul; 42(15):2946-60. PubMed ID: 10425104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and antitumor activity of duocarmycin derivatives: modification of segment A of duocarmycin B2.
    Nagamura S; Asai A; Kanda Y; Kobayashi E; Gomi K; Saito H
    Chem Pharm Bull (Tokyo); 1996 Sep; 44(9):1723-30. PubMed ID: 8855367
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and antitumor activity of duocarmycin derivatives.
    Nagamura S; Kanda Y; Kobayashi E; Gomi K; Saito H
    Chem Pharm Bull (Tokyo); 1995 Sep; 43(9):1530-5. PubMed ID: 7586077
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Studies on duocarmycin SA and its derivatives.
    Nagamura S; Asai A; Kobayashi E; Gomi K; Saito H
    Bioorg Med Chem; 1997 Mar; 5(3):623-30. PubMed ID: 9113339
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and antitumor activity of water-soluble duocarmycin B1 prodrugs.
    Asai A; Nagamura S; Kobayashi E; Gomi K; Saito H
    Bioorg Med Chem Lett; 1999 Oct; 9(20):2995-8. PubMed ID: 10571162
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characteristics of antitumor activity of KW-2189, a novel water-soluble derivative of duocarmycin, against murine and human tumors.
    Kobayashi E; Okamoto A; Asada M; Okabe M; Nagamura S; Asai A; Saito H; Gomi K; Hirata T
    Cancer Res; 1994 May; 54(9):2404-10. PubMed ID: 8162588
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, chemical properties, and biological evaluation of CC-1065 and duocarmycin analogues incorporating the 5-methoxycarbonyl-1,2,9,9a-tetrahydrocyclopropa.
    Boger DL; Hughes TV; Hedrick MP
    J Org Chem; 2001 Apr; 66(7):2207-16. PubMed ID: 11281757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of a series of C3-substituted CBI analogues of CC-1065 and the duocarmycins.
    Boger DL; Brunette SR; Garbaccio RM
    J Org Chem; 2001 Jul; 66(15):5163-73. PubMed ID: 11463270
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recent developments in novel pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis and biological evaluation.
    Kumar R; Lown JW
    Mini Rev Med Chem; 2003 Jun; 3(4):323-39. PubMed ID: 12678826
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.
    Ichimura M; Ogawa T; Takahashi K; Mihara A; Takahashi I; Nakano H
    Oncol Res; 1993; 5(4-5):165-71. PubMed ID: 8305742
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and Anti-cancer Activity of 3-substituted Benzoyl-4-substituted Phenyl-1H-pyrrole Derivatives.
    Zhan X; Qin W; Wang S; Zhao K; Xin Y; Wang Y; Qi Q; Mao Z
    Anticancer Agents Med Chem; 2017; 17(6):821-831. PubMed ID: 27671311
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunits.
    Parrish JP; Hughes TV; Hwang I; Boger DL
    J Am Chem Soc; 2004 Jan; 126(1):80-1. PubMed ID: 14709069
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substituent effects within the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065.
    Boger DL; Stauffer F; Hedrick MP
    Bioorg Med Chem Lett; 2001 Aug; 11(15):2021-4. PubMed ID: 11454471
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.