BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

89 related articles for article (PubMed ID: 10731721)

  • 1. Development of a new inhibitor of glucosylceramide synthase.
    Jimbo M; Yamagishi K; Yamaki T; Nunomura K; Kabayama K; Igarashi Y; Inokuchi JI
    J Biochem; 2000 Mar; 127(3):485-91. PubMed ID: 10731721
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological Modulation of Glycosphingolipid Metabolism.
    Inokuchi JI; Ode T; Hara-Yokoyama M
    Methods Mol Biol; 2018; 1804():401-410. PubMed ID: 29926420
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth.
    Abe A; Radin NS; Shayman JA; Wotring LL; Zipkin RE; Sivakumar R; Ruggieri JM; Carson KG; Ganem B
    J Lipid Res; 1995 Mar; 36(3):611-21. PubMed ID: 7775872
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Improved inhibitors of glucosylceramide synthase.
    Lee L; Abe A; Shayman JA
    J Biol Chem; 1999 May; 274(21):14662-9. PubMed ID: 10329660
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glycosphingolipid depletion in fabry disease lymphoblasts with potent inhibitors of glucosylceramide synthase.
    Abe A; Arend LJ; Lee L; Lingwood C; Brady RO; Shayman JA
    Kidney Int; 2000 Feb; 57(2):446-54. PubMed ID: 10652021
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stimulation of glycosphingolipid biosynthesis by L-threo-1-phenyl-2-decanoylamino-1-propanol and its homologs in B16 melanoma cells.
    Inokuchi J; Usuki S; Jimbo M
    J Biochem; 1995 Apr; 117(4):766-73. PubMed ID: 7592537
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glucosylceramide synthase inhibition enhances vincristine-induced cytotoxicity.
    Olshefski RS; Ladisch S
    Int J Cancer; 2001 Jul; 93(1):131-8. PubMed ID: 11391632
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucosylceramide synthase activity in murine epidermis: quantitation, localization, regulation, and requirement for barrier homeostasis.
    Chujor CS; Feingold KR; Elias PM; Holleran WM
    J Lipid Res; 1998 Feb; 39(2):277-85. PubMed ID: 9507988
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of an inhibitor of glucosylceramide synthesis on cultured human keratinocytes.
    Takami Y; Abe A; Matsuda T; Shayman JA; Radin NS; Walter RJ
    J Dermatol; 1998 Feb; 25(2):73-7. PubMed ID: 9563272
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disruption of the glucosylceramide biosynthetic pathway in Aspergillus nidulans and Aspergillus fumigatus by inhibitors of UDP-Glc:ceramide glucosyltransferase strongly affects spore germination, cell cycle, and hyphal growth.
    Levery SB; Momany M; Lindsey R; Toledo MS; Shayman JA; Fuller M; Brooks K; Doong RL; Straus AH; Takahashi HK
    FEBS Lett; 2002 Aug; 525(1-3):59-64. PubMed ID: 12163162
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of morpholino- and pyrrolidinosphingolipids as inhibitors of glucosylceramide synthase.
    Miura T; Kajimoto T; Jimbo M; Yamagishi K; Inokuchi JC; Wong CH
    Bioorg Med Chem; 1998 Sep; 6(9):1481-9. PubMed ID: 9801819
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of glucosylceramide synthase stimulates autophagy flux in neurons.
    Shen W; Henry AG; Paumier KL; Li L; Mou K; Dunlop J; Berger Z; Hirst WD
    J Neurochem; 2014 Jun; 129(5):884-94. PubMed ID: 24494600
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cholesterol-dependent increases in glucosylceramide synthase activity in Niemann-Pick disease type C model cells: Abnormal trafficking of endogenously formed ceramide metabolites by inhibition of the enzyme.
    Hashimoto N; Matsumoto I; Takahashi H; Ashikawa H; Nakamura H; Murayama T
    Neuropharmacology; 2016 Nov; 110(Pt A):458-469. PubMed ID: 27539961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific glycosphingolipids mediate epithelial-to-mesenchymal transition of human and mouse epithelial cell lines.
    Guan F; Handa K; Hakomori SI
    Proc Natl Acad Sci U S A; 2009 May; 106(18):7461-6. PubMed ID: 19380734
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential chemosensitizing effect of two glucosylceramide synthase inhibitors in hepatoma cells.
    di Bartolomeo S; Spinedi A
    Biochem Biophys Res Commun; 2001 Oct; 288(1):269-74. PubMed ID: 11594784
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A role for glycosphingolipid accumulation in the renal hypertrophy of streptozotocin-induced diabetes mellitus.
    Zador IZ; Deshmukh GD; Kunkel R; Johnson K; Radin NS; Shayman JA
    J Clin Invest; 1993 Mar; 91(3):797-803. PubMed ID: 8450061
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glucosylceramide synthase inhibitors D-PDMP and D-EtDO-P4 decrease the GM3 ganglioside level, differ in their effects on insulin receptor autophosphorylation but increase Akt1 kinase phosphorylation in human hepatoma HepG2 cells.
    Fedoryszak-Kuśka N; Panasiewicz M; Domek H; Pacuszka T
    Acta Biochim Pol; 2016; 63(2):247-51. PubMed ID: 27172362
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of phospholipase C-gamma activity by glycosphingolipids.
    Shu L; Lee L; Shayman JA
    J Biol Chem; 2002 May; 277(21):18447-53. PubMed ID: 11886852
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitors of glucosylceramide synthase.
    Shayman JA; Lee L; Abe A; Shu L
    Methods Enzymol; 2000; 311():373-87. PubMed ID: 10563341
    [No Abstract]   [Full Text] [Related]  

  • 20. Synthesis, shedding, and intercellular transfer of human medulloblastoma gangliosides: abrogation by a new inhibitor of glucosylceramide synthase.
    Olshefski R; Ladisch S
    J Neurochem; 1998 Feb; 70(2):467-72. PubMed ID: 9453539
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.