BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 10737741)

  • 1. Highly selective chiral N-substituted 3alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues for the dopamine transporter: synthesis and comparative molecular field analysis.
    Robarge MJ; Agoston GE; Izenwasser S; Kopajtic T; George C; Katz JL; Newman AH
    J Med Chem; 2000 Mar; 43(6):1085-93. PubMed ID: 10737741
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine transporter.
    Agoston GE; Wu JH; Izenwasser S; George C; Katz J; Kline RH; Newman AH
    J Med Chem; 1997 Dec; 40(26):4329-39. PubMed ID: 9435902
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationships at monoamine transporters and muscarinic receptors for N-substituted-3alpha-(3'-chloro-, 4'-chloro-, and 4',4''-dichloro-substituted-diphenyl)methoxytropanes.
    Newman AH; Robarge MJ; Howard IM; Wittkopp SL; George C; Kopajtic T; Izenwasser S; Katz JL
    J Med Chem; 2001 Feb; 44(4):633-40. PubMed ID: 11170654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
    Kulkarni SS; Grundt P; Kopajtic T; Katz JL; Newman AH
    J Med Chem; 2004 Jun; 47(13):3388-98. PubMed ID: 15189035
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation.
    Zou MF; Cao J; Kopajtic T; Desai RI; Katz JL; Newman AH
    J Med Chem; 2006 Oct; 49(21):6391-9. PubMed ID: 17034144
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel tropane-based irreversible ligands for the dopamine transporter.
    Zou MF; Kopajtic T; Katz JL; Wirtz S; Justice JB; Newman AH
    J Med Chem; 2001 Dec; 44(25):4453-61. PubMed ID: 11728190
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CoMFA study of novel phenyl ring-substituted 3alpha-(diphenylmethoxy)tropane analogues at the dopamine transporter.
    Newman AH; Izenwasser S; Robarge MJ; Kline RH
    J Med Chem; 1999 Sep; 42(18):3502-9. PubMed ID: 10479283
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationship comparison of (S)-2beta-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes and (R)-2beta-substituted 3beta-(3,4-dichlorophenyl)tropanes at the dopamine transporter.
    Zou MF; Kopajtic T; Katz JL; Newman AH
    J Med Chem; 2003 Jul; 46(14):2908-16. PubMed ID: 12825932
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.
    Kline RH; Izenwasser S; Katz JL; Joseph DB; Bowen WD; Newman AH
    J Med Chem; 1997 Mar; 40(6):851-7. PubMed ID: 9083473
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.
    Zhang Y; Joseph DB; Bowen WD; Flippen-Anderson JL; Dersch CM; Rothman RB; Jacobson AE; Rice KC
    J Med Chem; 2001 Nov; 44(23):3937-45. PubMed ID: 11689080
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enantioselective synthesis of S-(+)-2beta-carboalkoxy-3alpha-[bis(4-fluorophenyl)methoxy]tropanes as novel probes for the dopamine transporter.
    Zou MF; Agoston GE; Belov Y; Kopajtic T; Katz JL; Newman AH
    Bioorg Med Chem Lett; 2002 May; 12(9):1249-52. PubMed ID: 11965364
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 3-Aryl-2-(3'-substituted-1',2',4'-oxadiazol-5'-yl)tropane analogues of cocaine: affinities at the cocaine binding site at the dopamine, serotonin, and norepinephrine transporters.
    Carroll FI; Gray JL; Abraham P; Kuzemko MA; Lewin AH; Boja JW; Kuhar MJ
    J Med Chem; 1993 Oct; 36(20):2886-90. PubMed ID: 8411004
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.
    Husbands SM; Izenwasser S; Kopajtic T; Bowen WD; Vilner BJ; Katz JL; Newman AH
    J Med Chem; 1999 Oct; 42(21):4446-55. PubMed ID: 10543888
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, structure, dopamine transporter affinity, and dopamine uptake inhibition of 6-alkyl-3-benzyl-2-[(methoxycarbonyl)methyl]tropane derivatives.
    Lomenzo SA; Izenwasser S; Katz JL; Terry PD; Zhu N; Klein CL; Trudell ML
    J Med Chem; 1997 Dec; 40(26):4406-14. PubMed ID: 9435910
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter.
    Hoepping A; Johnson KM; George C; Flippen-Anderson J; Kozikowski AP
    J Med Chem; 2000 May; 43(10):2064-71. PubMed ID: 10821718
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and monoamine transporter binding of 2-(diarylmethoxymethyl)-3 beta-aryltropane derivatives.
    Xu L; Kulkarni SS; Izenwasser S; Katz JL; Kopajtic T; Lomenzo SA; Newman AH; Trudell ML
    J Med Chem; 2004 Mar; 47(7):1676-82. PubMed ID: 15027858
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.
    Zhang A; Zhou G; Hoepping A; Mukhopadhyaya J; Johnson KM; Zhang M; Kozikowski AP
    J Med Chem; 2002 Apr; 45(9):1930-41. PubMed ID: 11960503
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, biodistribution, and primate imaging of fluorine-18 labeled 2beta-carbo-1'-fluoro-2-propoxy-3beta-(4-chlorophenyl)tr opanes. Ligands for the imaging of dopamine transporters by positron emission tomography.
    Xing D; Chen P; Keil R; Kilts CD; Shi B; Camp VM; Malveaux G; Ely T; Owens MJ; Votaw J; Davis M; Hoffman JM; BaKay RA; Subramanian T; Watts RL; Goodman MM
    J Med Chem; 2000 Feb; 43(4):639-48. PubMed ID: 10691690
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel 3alpha-diphenylmethoxytropane analogs: selective dopamine uptake inhibitors with behavioral effects distinct from those of cocaine.
    Katz JL; Izenwasser S; Kline RH; Allen AC; Newman AH
    J Pharmacol Exp Ther; 1999 Jan; 288(1):302-15. PubMed ID: 9862785
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands.
    Katz JL; Kopajtic TA; Agoston GE; Newman AH
    J Pharmacol Exp Ther; 2004 May; 309(2):650-60. PubMed ID: 14755006
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.