149 related articles for article (PubMed ID: 10744044)
1. Immunohistochemical detection of carcinogen-DNA adducts in normal human prostate tissues transplanted into the subcutis of athymic nude mice: results with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 3,2'-dimethyl-4-aminobiphenyl (DMAB) and relation to cytochrome P450s and N-acetyltransferase activity.
Cui L; Takahashi S; Tada M; Kato K; Yamada Y; Kohri K; Shirai T
Jpn J Cancer Res; 2000 Jan; 91(1):52-8. PubMed ID: 10744044
[TBL] [Abstract][Full Text] [Related]
2. 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced DNA adducts and genotoxicity in chinese hamster ovary (CHO) cells expressing human CYP1A2 and rapid or slow acetylator N-acetyltransferase 2.
Metry KJ; Zhao S; Neale JR; Doll MA; States JC; McGregor WG; Pierce WM; Hein DW
Mol Carcinog; 2007 Jul; 46(7):553-63. PubMed ID: 17295238
[TBL] [Abstract][Full Text] [Related]
3. Organ dependent enhancement of rat 3,2'-dimethyl-4-aminobiphenyl (DMAB) carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): positive effects on the intestine but not the prostate.
Imaida K; Sano M; Tamano S; Asamoto M; Ogawa K; Futakuchi M; Shirai T
Carcinogenesis; 2001 Aug; 22(8):1295-9. PubMed ID: 11470761
[TBL] [Abstract][Full Text] [Related]
4. Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse.
Leff MA; Epstein PN; Doll MA; Fretland AJ; Devanaboyina US; Rustan TD; Hein DW
J Pharmacol Exp Ther; 1999 Jul; 290(1):182-7. PubMed ID: 10381774
[TBL] [Abstract][Full Text] [Related]
5. Role of human CYP1A1 and NAT2 in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutagenicity and DNA adducts.
Bendaly J; Metry KJ; Doll MA; Jiang G; States JC; Smith NB; Neale JR; Holloman JL; Pierce WM; Hein DW
Xenobiotica; 2009 May; 39(5):399-406. PubMed ID: 19301197
[TBL] [Abstract][Full Text] [Related]
6. Excretion of the N(2)-glucuronide conjugate of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in urine and its relationship to CYP1A2 and NAT2 activity levels in humans.
Stillwell WG; Sinha R; Tannenbaum SR
Carcinogenesis; 2002 May; 23(5):831-8. PubMed ID: 12016157
[TBL] [Abstract][Full Text] [Related]
7. Metabolic activation and DNA adduct detection of PhIP in dogs, rats, and humans in relation to urinary bladder and colon carcinogenesis.
Kadlubar F; Kaderlik RK; Mulder GJ; Lin D; Butler MA; Teitel CH; Minchin RF; Ilett KF; Friesen MD; Bartsch H
Princess Takamatsu Symp; 1995; 23():207-13. PubMed ID: 8844812
[TBL] [Abstract][Full Text] [Related]
8. N-Acetyltransferase expression and DNA binding of N-hydroxyheterocyclic amines in human prostate epithelium.
Wang CY; Debiec-Rychter M; Schut HA; Morse P; Jones RF; Archer C; King CM; Haas GP
Carcinogenesis; 1999 Aug; 20(8):1591-5. PubMed ID: 10426812
[TBL] [Abstract][Full Text] [Related]
9. Use of polyclonal antibodies against carcinogen-DNA adducts in analysis of carcinogenesis.
Shirai T; Takahashi S; Cui L; Yamada Y; Tada M; Kadlubar FF; Ito N
Toxicol Lett; 1998 Dec; 102-103():441-6. PubMed ID: 10022293
[TBL] [Abstract][Full Text] [Related]
10. Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.
Metry KJ; Neale JR; Bendaly J; Smith NB; Pierce WM; Hein DW
Drug Metab Dispos; 2009 Nov; 37(11):2123-6. PubMed ID: 19666988
[TBL] [Abstract][Full Text] [Related]
11. Metabolic Activation of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Human Prostate.
Bellamri M; Xiao S; Murugan P; Weight CJ; Turesky RJ
Toxicol Sci; 2018 Jun; 163(2):543-556. PubMed ID: 29596660
[TBL] [Abstract][Full Text] [Related]
12. DNA adducts of the tobacco carcinogens 2-amino-9H-pyrido[2,3-b]indole and 4-aminobiphenyl are formed at environmental exposure levels and persist in human hepatocytes.
Nauwelaërs G; Bellamri M; Fessard V; Turesky RJ; Langouët S
Chem Res Toxicol; 2013 Sep; 26(9):1367-77. PubMed ID: 23898916
[TBL] [Abstract][Full Text] [Related]
13. Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
Fretland AJ; Devanaboyina US; Doll MA; Zhao S; Xiao GH; Hein DW
Toxicol Sci; 2003 Aug; 74(2):253-9. PubMed ID: 12773763
[TBL] [Abstract][Full Text] [Related]
14. Biomonitoring DNA Adducts of Cooked Meat Carcinogens in Human Prostate by Nano Liquid Chromatography-High Resolution Tandem Mass Spectrometry: Identification of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine DNA Adduct.
Xiao S; Guo J; Yun BH; Villalta PW; Krishna S; Tejpaul R; Murugan P; Weight CJ; Turesky RJ
Anal Chem; 2016 Dec; 88(24):12508-12515. PubMed ID: 28139123
[TBL] [Abstract][Full Text] [Related]
15. Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes.
Bacon JR; Williamson G; Garner RC; Lappin G; Langouët S; Bao Y
Carcinogenesis; 2003 Dec; 24(12):1903-11. PubMed ID: 12949046
[TBL] [Abstract][Full Text] [Related]
16. Human prostate epithelial cells metabolize chemicals of dietary origin to mutagens.
Lawson T; Kolar C
Cancer Lett; 2002 Jan; 175(2):141-6. PubMed ID: 11741741
[TBL] [Abstract][Full Text] [Related]
17. Oral administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) yields PhIP-DNA adducts but not tumors in male Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
Fretland AJ; Devanaboyina US; Feng Y; Leff MA; Xiao GH; Webb SJ; Hein DW
Toxicol Sci; 2001 Feb; 59(2):226-30. PubMed ID: 11158715
[TBL] [Abstract][Full Text] [Related]
18. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans.
Malfatti MA; Dingley KH; Nowell-Kadlubar S; Ubick EA; Mulakken N; Nelson D; Lang NP; Felton JS; Turteltaub KW
Cancer Res; 2006 Nov; 66(21):10541-7. PubMed ID: 17079477
[TBL] [Abstract][Full Text] [Related]
19. Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells.
Stone EM; Williams JA; Grover PL; Gusterson BA; Phillips DH
Carcinogenesis; 1998 May; 19(5):873-9. PubMed ID: 9635877
[TBL] [Abstract][Full Text] [Related]
20. The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats.
Turesky RJ; Richoz J; Constable A; Curtis KD; Dingley KH; Turteltaub KW
Chem Biol Interact; 2003 Jun; 145(3):251-65. PubMed ID: 12732453
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]