BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 10746933)

  • 1. Sensitivity analysis of a physiological model for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): assessing the impact of specific model parameters on sequestration in liver and fat in the rat.
    Evans MV; Andersen ME
    Toxicol Sci; 2000 Mar; 54(1):71-80. PubMed ID: 10746933
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Use of a physiologically based pharmacokinetic model for rats to study the influence of body fat mass and induction of CYP1A2 on the pharmacokinetics of TCDD.
    Emond C; Birnbaum LS; DeVito MJ
    Environ Health Perspect; 2006 Sep; 114(9):1394-400. PubMed ID: 16966094
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Physiological modeling of a proposed mechanism of enzyme induction by TCDD.
    Kohn MC; Walker NJ; Kim AH; Portier CJ
    Toxicology; 2001 May; 162(3):193-208. PubMed ID: 11369115
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The effect of dose on 2,3,7,8-TCDD tissue distribution, metabolism and elimination in CYP1A2 (-/-) knockout and C57BL/6N parental strains of mice.
    Hakk H; Diliberto JJ; Birnbaum LS
    Toxicol Appl Pharmacol; 2009 Nov; 241(1):119-26. PubMed ID: 19695277
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Determination of parameters responsible for pharmacokinetic behavior of TCDD in female Sprague-Dawley rats.
    Wang X; Santostefano MJ; Evans MV; Richardson VM; Diliberto JJ; Birnbaum LS
    Toxicol Appl Pharmacol; 1997 Nov; 147(1):151-68. PubMed ID: 9356318
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A mechanistic model of effects of dioxin on thyroid hormones in the rat.
    Kohn MC; Sewall CH; Lucier GW; Portier CJ
    Toxicol Appl Pharmacol; 1996 Jan; 136(1):29-48. PubMed ID: 8560478
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Time- and concentration-dependent induction of CYP1A1 and CYP1A2 in precision-cut rat liver slices incubated in dynamic organ culture in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Drahushuk AT; McGarrigle BP; Slezak BP; Stegeman JJ; Olson JR
    Toxicol Appl Pharmacol; 1999 Mar; 155(2):127-38. PubMed ID: 10053167
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin evaluated with a multicompartment geometric model of hepatic zonation.
    Andersen ME; Birnbaum LS; Barton HA; Eklund CR
    Toxicol Appl Pharmacol; 1997 May; 144(1):145-55. PubMed ID: 9169078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A pharmacodynamic analysis of TCDD-induced cytochrome P450 gene expression in multiple tissues: dose- and time-dependent effects.
    Santostefano MJ; Wang X; Richardson VM; Ross DG; DeVito MJ; Birnbaum LS
    Toxicol Appl Pharmacol; 1998 Aug; 151(2):294-310. PubMed ID: 9707506
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A physiological pharmacokinetic description of the tissue distribution and enzyme-inducing properties of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat.
    Leung HW; Paustenbach DJ; Murray FJ; Andersen ME
    Toxicol Appl Pharmacol; 1990 May; 103(3):399-410. PubMed ID: 2160135
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A pharmacodynamically responsive model of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) transfer between liver and fat at low and high doses.
    Roth WL; Ernst S; Weber LW; Kerecsen L; Rozman KK
    Toxicol Appl Pharmacol; 1994 Jul; 127(1):151-62. PubMed ID: 8048047
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice.
    Diliberto JJ; Akubue PI; Luebke RW; Birnbaum LS
    Toxicol Appl Pharmacol; 1995 Feb; 130(2):197-208. PubMed ID: 7871533
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver.
    Tritscher AM; Goldstein JA; Portier CJ; McCoy Z; Clark GC; Lucier GW
    Cancer Res; 1992 Jun; 52(12):3436-42. PubMed ID: 1596902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A physiologically based pharmacokinetic model for 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in the rat: tissue distribution and CYP1A induction.
    Kedderis LB; Mills JJ; Andersen ME; Birnbaum LS
    Toxicol Appl Pharmacol; 1993 Jul; 121(1):87-98. PubMed ID: 8337704
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NTP technical report on the toxicology and carcinogenesis studies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (CAS No. 1746-01-6) in female Harlan Sprague-Dawley rats (Gavage Studies).
    National Toxicology Program
    Natl Toxicol Program Tech Rep Ser; 2006 Apr; (521):4-232. PubMed ID: 16835633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Walker NJ; Portier CJ; Lax SF; Crofts FG; Li Y; Lucier GW; Sutter TR
    Toxicol Appl Pharmacol; 1999 Feb; 154(3):279-86. PubMed ID: 9931287
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disposition of 2,3,7,8-tetrabromodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat: biliary excretion and induction of cytochromes CYP1A1 and CYP1A2.
    Kedderis LB; Diliberto JJ; Linko P; Goldstein JA; Birnbaum LS
    Toxicol Appl Pharmacol; 1991 Oct; 111(1):163-72. PubMed ID: 1949032
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Extrapolation of a PBPK model for dioxins across dosage regimen, gender, strain, and species.
    Wang X; Santostefano MJ; DeVito MJ; Birnbaum LS
    Toxicol Sci; 2000 Jul; 56(1):49-60. PubMed ID: 10869453
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A mechanistic model of effects of dioxin on gene expression in the rat liver.
    Kohn MC; Lucier GW; Clark GC; Sewall C; Tritscher AM; Portier CJ
    Toxicol Appl Pharmacol; 1993 May; 120(1):138-54. PubMed ID: 8511776
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tissue distribution after a single subcutaneous administration of 2,3,7,8-tetrabromodibenzo-p-dioxin in comparison with toxicokinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Wistar rats.
    Nagao T; Yamashita K; Golor G; Bittmann H; Körner W; Hagenmaier H; Neubert D
    Life Sci; 1996; 58(4):325-36. PubMed ID: 8538369
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.