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2. Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion. Williams TM; Medina F; Badano I; Hazan RB; Hutchinson J; Muller WJ; Chopra NG; Scherer PE; Pestell RG; Lisanti MP J Biol Chem; 2004 Dec; 279(49):51630-46. PubMed ID: 15355971 [TBL] [Abstract][Full Text] [Related]
3. Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. Galbiati F; Volonte D; Engelman JA; Watanabe G; Burk R; Pestell RG; Lisanti MP EMBO J; 1998 Nov; 17(22):6633-48. PubMed ID: 9822607 [TBL] [Abstract][Full Text] [Related]
4. Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain. Engelman JA; Chu C; Lin A; Jo H; Ikezu T; Okamoto T; Kohtz DS; Lisanti MP FEBS Lett; 1998 May; 428(3):205-11. PubMed ID: 9654135 [TBL] [Abstract][Full Text] [Related]
5. Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation. Capozza F; Williams TM; Schubert W; McClain S; Bouzahzah B; Sotgia F; Lisanti MP Am J Pathol; 2003 Jun; 162(6):2029-39. PubMed ID: 12759258 [TBL] [Abstract][Full Text] [Related]
6. Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers. Engelman JA; Zhang XL; Lisanti MP FEBS Lett; 1998 Oct; 436(3):403-10. PubMed ID: 9801158 [TBL] [Abstract][Full Text] [Related]
7. Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice. Williams TM; Cheung MW; Park DS; Razani B; Cohen AW; Muller WJ; Di Vizio D; Chopra NG; Pestell RG; Lisanti MP Mol Biol Cell; 2003 Mar; 14(3):1027-42. PubMed ID: 12631721 [TBL] [Abstract][Full Text] [Related]
9. Up-regulation of caveolin attenuates epidermal growth factor signaling in senescent cells. Park WY; Park JS; Cho KA; Kim DI; Ko YG; Seo JS; Park SC J Biol Chem; 2000 Jul; 275(27):20847-52. PubMed ID: 10781609 [TBL] [Abstract][Full Text] [Related]
10. Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines. Engelman JA; Zhang XL; Lisanti MP FEBS Lett; 1999 Apr; 448(2-3):221-30. PubMed ID: 10218480 [TBL] [Abstract][Full Text] [Related]
12. Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia. Williams TM; Lee H; Cheung MW; Cohen AW; Razani B; Iyengar P; Scherer PE; Pestell RG; Lisanti MP J Biol Chem; 2004 Jun; 279(23):24745-56. PubMed ID: 15044451 [TBL] [Abstract][Full Text] [Related]
13. p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity. Engelman JA; Zhang XL; Razani B; Pestell RG; Lisanti MP J Biol Chem; 1999 Nov; 274(45):32333-41. PubMed ID: 10542274 [TBL] [Abstract][Full Text] [Related]
14. Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells. Fiucci G; Ravid D; Reich R; Liscovitch M Oncogene; 2002 Apr; 21(15):2365-75. PubMed ID: 11948420 [TBL] [Abstract][Full Text] [Related]
15. Rapid effects of EGF on cytoskeletal structures and adhesive properties of highly metastatic rat mammary adenocarcinoma cells. Lichtner RB; Wiedemuth M; Noeske-Jungblut C; Schirrmacher V Clin Exp Metastasis; 1993 Jan; 11(1):113-25. PubMed ID: 8422702 [TBL] [Abstract][Full Text] [Related]
16. Attenuation of EGF signaling in senescent cells by caveolin. Park WY; Cho KA; Park JS; Kim DI; Park SC Ann N Y Acad Sci; 2001 Apr; 928():79-84. PubMed ID: 11795531 [TBL] [Abstract][Full Text] [Related]
17. N-terminal domains of the class ia phosphoinositide 3-kinase regulatory subunit play a role in cytoskeletal but not mitogenic signaling. Hill KM; Huang Y; Yip SC; Yu J; Segall JE; Backer JM J Biol Chem; 2001 May; 276(19):16374-8. PubMed ID: 11278326 [TBL] [Abstract][Full Text] [Related]
18. Regulation of protrusion shape and adhesion to the substratum during chemotactic responses of mammalian carcinoma cells. Bailly M; Yan L; Whitesides GM; Condeelis JS; Segall JE Exp Cell Res; 1998 Jun; 241(2):285-99. PubMed ID: 9637770 [TBL] [Abstract][Full Text] [Related]
19. EGF enhances attachment of metastatic rat mammary adenocarcinoma cell clone MTLn3 to fibronectin and collagen. Rohde-Schulz B; Lichtner RB Invasion Metastasis; 1995; 15(1-2):1-10. PubMed ID: 7672928 [TBL] [Abstract][Full Text] [Related]
20. Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. Lee H; Park DS; Razani B; Russell RG; Pestell RG; Lisanti MP Am J Pathol; 2002 Oct; 161(4):1357-69. PubMed ID: 12368209 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]