BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 10749122)

  • 1. Transfection of constitutively active mitogen-activated protein/extracellular signal-regulated kinase kinase confers tumorigenic and metastatic potentials to NIH3T3 cells.
    Welch DR; Sakamaki T; Pioquinto R; Leonard TO; Goldberg SF; Hon Q; Erikson RL; Rieber M; Rieber MS; Hicks DJ; Bonventre JV; Alessandrini A
    Cancer Res; 2000 Mar; 60(6):1552-6. PubMed ID: 10749122
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mek1 phosphorylation site mutants activate Raf-1 in NIH 3T3 cells.
    Alessandrini A; Greulich H; Huang W; Erikson RL
    J Biol Chem; 1996 Dec; 271(49):31612-8. PubMed ID: 8940180
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
    Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.
    Ikenoue T; Hikiba Y; Kanai F; Aragaki J; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Matsumura M; Kawabe T; Omata M
    Cancer Res; 2004 May; 64(10):3428-35. PubMed ID: 15150094
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEK1 signaling mediates transformation and metastasis of EpH4 mammary epithelial cells independent of an epithelial to mesenchymal transition.
    Pinkas J; Leder P
    Cancer Res; 2002 Aug; 62(16):4781-90. PubMed ID: 12183438
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Malolactomycin D, a potent inhibitor of transcription controlled by the Ras responsive element, inhibits Ras-mediated transformation activity with suppression of MMP-1 and MMP-9 in NIH3T3 cells.
    Futamura M; Kamiya S; Tsukamoto M; Hirano A; Monden Y; Arakawa H; Nishimura S
    Oncogene; 2001 Oct; 20(46):6724-30. PubMed ID: 11709707
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MEK1 and the extracellular signal-regulated kinases are required for the stimulation of IL-2 gene transcription in T cells.
    Whitehurst CE; Geppert TD
    J Immunol; 1996 Feb; 156(3):1020-9. PubMed ID: 8557975
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MAP kinase activation is essential for oncogenic transformation of NIH3T3 cells by Mos.
    Okazaki K; Sagata N
    Oncogene; 1995 Mar; 10(6):1149-57. PubMed ID: 7700641
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R; Piperdi S; Gorlick R
    Clin Cancer Res; 2008 Oct; 14(20):6396-404. PubMed ID: 18927278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation.
    Robinson MJ; Stippec SA; Goldsmith E; White MA; Cobb MH
    Curr Biol; 1998 Oct; 8(21):1141-50. PubMed ID: 9799732
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biochemical and biological analysis of Mek1 phosphorylation site mutants.
    Huang W; Kessler DS; Erikson RL
    Mol Biol Cell; 1995 Mar; 6(3):237-45. PubMed ID: 7612960
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Signaling pathways in Ras-mediated tumorigenicity and metastasis.
    Webb CP; Van Aelst L; Wigler MH; Vande Woude GF
    Proc Natl Acad Sci U S A; 1998 Jul; 95(15):8773-8. PubMed ID: 9671754
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells.
    Plattner R; Gupta S; Khosravi-Far R; Sato KY; Perucho M; Der CJ; Stanbridge EJ
    Oncogene; 1999 Mar; 18(10):1807-17. PubMed ID: 10086335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reversion of Ras- and phosphatidylcholine-hydrolyzing phospholipase C-mediated transformation of NIH 3T3 cells by a dominant interfering mutant of protein kinase C lambda is accompanied by the loss of constitutive nuclear mitogen-activated protein kinase/extracellular signal-regulated kinase activity.
    Bjorkoy G; Perander M; Overvatn A; Johansen T
    J Biol Chem; 1997 Apr; 272(17):11557-65. PubMed ID: 9111071
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular assembly of mitogen-activated protein kinase module in ras-transformed NIH3T3 cell line.
    Park KS; Kim JA; Chai KJ
    Exp Mol Med; 2000 Sep; 32(3):120-6. PubMed ID: 11048642
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposing roles of Ras/Raf oncogenes and the MEK1/ERK signaling module in regulation of expression and adhesive function of surface transglutaminase.
    Akimov SS; Belkin AM
    J Biol Chem; 2003 Sep; 278(37):35609-19. PubMed ID: 12832399
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cot protooncoprotein activates the dual specificity kinases MEK-1 and SEK-1 and induces differentiation of PC12 cells.
    Hagemann D; Troppmair J; Rapp UR
    Oncogene; 1999 Feb; 18(7):1391-400. PubMed ID: 10050876
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SCH 51344 inhibits ras transformation by a novel mechanism.
    Kumar CC; Prorock-Rogers C; Kelly J; Dong Z; Lin JJ; Armstrong L; Kung HF; Weber MJ; Afonso A
    Cancer Res; 1995 Nov; 55(21):5106-17. PubMed ID: 7585559
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Signal pathways which promote invasion and metastasis: critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways.
    Ward Y; Wang W; Woodhouse E; Linnoila I; Liotta L; Kelly K
    Mol Cell Biol; 2001 Sep; 21(17):5958-69. PubMed ID: 11486034
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reversible regulation of the transformed phenotype of ornithine decarboxylase- and ras-overexpressing cells by dominant-negative mutants of c-Jun.
    Kielosto M; Nummela P; Katainen R; Leaner V; Birrer MJ; Hölttä E
    Cancer Res; 2004 Jun; 64(11):3772-9. PubMed ID: 15172983
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.