BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 10749126)

  • 1. Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: genotype-specific effects on cancer predisposition and pathology of tumors.
    Cheo DL; Meira LB; Burns DK; Reis AM; Issac T; Friedberg EC
    Cancer Res; 2000 Mar; 60(6):1580-4. PubMed ID: 10749126
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genotype-specific Trp53 mutational analysis in ultraviolet B radiation-induced skin cancers in Xpc and Xpc Trp53 mutant mice.
    Reis AM; Cheo DL; Meira LB; Greenblatt MS; Bond JP; Nahari D; Friedberg EC
    Cancer Res; 2000 Mar; 60(6):1571-9. PubMed ID: 10749125
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutations in the Trp53 gene of UV-irradiated Xpc mutant mice suggest a novel Xpc-dependent DNA repair process.
    Nahari D; McDaniel LD; Task LB; Daniel RL; Velasco-Miguel S; Friedberg EC
    DNA Repair (Amst); 2004 Apr; 3(4):379-86. PubMed ID: 15010313
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Persistence of p53 mutations and resistance of keratinocytes to apoptosis are associated with the increased susceptibility of mice lacking the XPC gene to UV carcinogenesis.
    Ananthaswamy HN; Ouhtit A; Evans RL; Gorny A; Khaskina P; Sands AT; Conti CJ
    Oncogene; 1999 Dec; 18(51):7395-8. PubMed ID: 10602497
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutational inactivation of the xeroderma pigmentosum group C gene confers predisposition to 2-acetylaminofluorene-induced liver and lung cancer and to spontaneous testicular cancer in Trp53-/- mice.
    Cheo DL; Burns DK; Meira LB; Houle JF; Friedberg EC
    Cancer Res; 1999 Feb; 59(4):771-5. PubMed ID: 10029060
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity.
    Rebel H; Mosnier LO; Berg RJ; Westerman-de Vries A; van Steeg H; van Kranen HJ; de Gruijl FR
    Cancer Res; 2001 Feb; 61(3):977-83. PubMed ID: 11221893
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions.
    Meira LB; Reis AM; Cheo DL; Nahari D; Burns DK; Friedberg EC
    Mutat Res; 2001 Jun; 477(1-2):51-8. PubMed ID: 11376686
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p53 protects against skin cancer induction by UV-B radiation.
    Jiang W; Ananthaswamy HN; Muller HK; Kripke ML
    Oncogene; 1999 Jul; 18(29):4247-53. PubMed ID: 10435637
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice.
    Rebel H; Kram N; Westerman A; Banus S; van Kranen HJ; de Gruijl FR
    Carcinogenesis; 2005 Dec; 26(12):2123-30. PubMed ID: 16051635
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Frequent recovery of triplet mutations in UVB-exposed skin epidermis of Xpc-knockout mice.
    Ikehata H; Saito Y; Yanase F; Mori T; Nikaido O; Ono T
    DNA Repair (Amst); 2007 Jan; 6(1):82-93. PubMed ID: 17049932
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Defective nucleotide excision repair in xpc mutant mice and its association with cancer predisposition.
    Friedberg EC; Bond JP; Burns DK; Cheo DL; Greenblatt MS; Meira LB; Nahari D; Reis AM
    Mutat Res; 2000 Mar; 459(2):99-108. PubMed ID: 10725660
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC.
    Sands AT; Abuin A; Sanchez A; Conti CJ; Bradley A
    Nature; 1995 Sep; 377(6545):162-5. PubMed ID: 7675084
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice.
    Kramata P; Lu YP; Lou YR; Singh RN; Kwon SM; Conney AH
    Cancer Res; 2005 May; 65(9):3577-85. PubMed ID: 15867351
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fate of UVB-induced p53 mutations in SKH-hr1 mouse skin after discontinuation of irradiation: relationship to skin cancer development.
    Melnikova VO; Pacifico A; Chimenti S; Peris K; Ananthaswamy HN
    Oncogene; 2005 Oct; 24(47):7055-63. PubMed ID: 16007135
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice.
    Berg RJ; Rebel H; van der Horst GT; van Kranen HJ; Mullenders LH; van Vloten WA; de Gruijl FR
    Cancer Res; 2000 Jun; 60(11):2858-63. PubMed ID: 10850428
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of UV induced lesions in skin carcinogenesis: an overview of oncogene and tumor suppressor gene modifications in xeroderma pigmentosum skin tumors.
    Daya-Grosjean L; Sarasin A
    Mutat Res; 2005 Apr; 571(1-2):43-56. PubMed ID: 15748637
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions.
    Inga A; Nahari D; Velasco-Miguel S; Friedberg EC; Resnick MA
    Oncogene; 2002 Aug; 21(37):5704-15. PubMed ID: 12173040
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Apoptosis, UV-radiation, precancerosis and skin tumors].
    Tomas D
    Acta Med Croatica; 2009 Oct; 63 Suppl 2():53-8. PubMed ID: 19999548
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.
    Wikonkal NM; Remenyik E; Knezevic D; Zhang W; Liu M; Zhao H; Berton TR; Johnson DG; Brash DE
    Nat Cell Biol; 2003 Jul; 5(7):655-60. PubMed ID: 12833065
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Strand specificity and absence of hot spots for p53 mutations in ultraviolet B-induced skin tumors of XPA-deficient mice.
    Takeuchi S; Nakatsu Y; Nakane H; Murai H; Hirota S; Kitamura Y; Okuyama A; Tanaka K
    Cancer Res; 1998 Feb; 58(4):641-6. PubMed ID: 9485015
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.