487 related articles for article (PubMed ID: 10751437)
1. Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
Tanaka T; Tatsuno I; Uchida D; Moroo I; Morio H; Nakamura S; Noguchi Y; Yasuda T; Kitagawa M; Saito Y; Hirai A
J Neurosci; 2000 Apr; 20(8):2852-9. PubMed ID: 10751437
[TBL] [Abstract][Full Text] [Related]
2. Statins inhibit blastocyst formation by preventing geranylgeranylation.
Alarcon VB; Marikawa Y
Mol Hum Reprod; 2016 May; 22(5):350-63. PubMed ID: 26908642
[TBL] [Abstract][Full Text] [Related]
3. Geranylgeranylpyrophosphate, a metabolite of mevalonate, regulates the cell cycle progression and DNA synthesis in human lymphocytes.
Tatsuno I; Tanaka T; Oeda T; Yasuda T; Kitagawa M; Saito Y; Hirai A
Biochem Biophys Res Commun; 1997 Dec; 241(2):376-82. PubMed ID: 9425279
[TBL] [Abstract][Full Text] [Related]
4. Mevalonate Cascade and its Regulation in Cholesterol Metabolism in Different Tissues in Health and Disease.
Hashemi M; Hoshyar R; Ande SR; Chen QM; Solomon C; Zuse A; Naderi M
Curr Mol Pharmacol; 2017; 10(1):13-26. PubMed ID: 26758949
[TBL] [Abstract][Full Text] [Related]
5. HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis.
Schulz JG; Bösel J; Stoeckel M; Megow D; Dirnagl U; Endres M
J Neurochem; 2004 Apr; 89(1):24-32. PubMed ID: 15030386
[TBL] [Abstract][Full Text] [Related]
6. Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells.
Xia Z; Tan MM; Wong WW; Dimitroulakos J; Minden MD; Penn LZ
Leukemia; 2001 Sep; 15(9):1398-407. PubMed ID: 11516100
[TBL] [Abstract][Full Text] [Related]
7. HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway.
Qi XF; Zheng L; Lee KJ; Kim DH; Kim CS; Cai DQ; Wu Z; Qin JW; Yu YH; Kim SK
Cell Death Dis; 2013 Feb; 4(2):e518. PubMed ID: 23449454
[TBL] [Abstract][Full Text] [Related]
8. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase.
Laufs U; Liao JK
J Biol Chem; 1998 Sep; 273(37):24266-71. PubMed ID: 9727051
[TBL] [Abstract][Full Text] [Related]
9. Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux.
Argmann CA; Edwards JY; Sawyez CG; O'Neil CH; Hegele RA; Pickering JG; Huff MW
J Biol Chem; 2005 Jun; 280(23):22212-21. PubMed ID: 15817453
[TBL] [Abstract][Full Text] [Related]
10. Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase.
Kato S; Smalley S; Sadarangani A; Chen-Lin K; Oliva B; Brañes J; Carvajal J; Gejman R; Owen GI; Cuello M
J Cell Mol Med; 2010 May; 14(5):1180-93. PubMed ID: 19432822
[TBL] [Abstract][Full Text] [Related]
11. Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells.
Gbelcová H; Rimpelová S; Knejzlík Z; Šáchová J; Kolář M; Strnad H; Repiská V; D'Acunto WC; Ruml T; Vítek L
Lipids Health Dis; 2017 Dec; 16(1):250. PubMed ID: 29262834
[TBL] [Abstract][Full Text] [Related]
12. Geranylgeranylpyrophosphate plays a key role for the G1 to S transition in vascular smooth muscle cells.
Terano T; Shiina T; Noguchi Y; Tanaka T; Tatsuno I; Saito Y; Yasuda T; Kitagawa M; Hirai A
J Atheroscler Thromb; 1998; 5(1):1-6. PubMed ID: 10077451
[TBL] [Abstract][Full Text] [Related]
13. Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas.
Dimitroulakos J; Marhin WH; Tokunaga J; Irish J; Gullane P; Penn LZ; Kamel-Reid S
Neoplasia; 2002; 4(4):337-46. PubMed ID: 12082550
[TBL] [Abstract][Full Text] [Related]
14. Effects of farnesyl pyrophosphate accumulation on calvarial osteoblast differentiation.
Weivoda MM; Hohl RJ
Endocrinology; 2011 Aug; 152(8):3113-22. PubMed ID: 21586555
[TBL] [Abstract][Full Text] [Related]
15. HMG CoA reductase inhibitor-induced myotoxicity: pravastatin and lovastatin inhibit the geranylgeranylation of low-molecular-weight proteins in neonatal rat muscle cell culture.
Flint OP; Masters BA; Gregg RE; Durham SK
Toxicol Appl Pharmacol; 1997 Jul; 145(1):99-110. PubMed ID: 9221829
[TBL] [Abstract][Full Text] [Related]
16. Importance of geranylgeranyl pyrophosphate for mesangial cell DNA synthesis.
Massy ZA; Guijarro C; Oda H; Kasiske BL; Keane WF; O'Donnell MP
Kidney Int Suppl; 1999 Jul; 71():S80-3. PubMed ID: 10412744
[TBL] [Abstract][Full Text] [Related]
17. Effect of pravastatin on type IV collagen secretion and mesangial cell proliferation.
Nishimura M; Tanaka T; Yasuda T; Kurakata S; Kitagawa M; Yamada K; Saito Y; Hirai A
Kidney Int Suppl; 1999 Jul; 71():S97-100. PubMed ID: 10412748
[TBL] [Abstract][Full Text] [Related]
18. Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins).
Eberlein M; Heusinger-Ribeiro J; Goppelt-Struebe M
Br J Pharmacol; 2001 Aug; 133(7):1172-80. PubMed ID: 11487529
[TBL] [Abstract][Full Text] [Related]
19. 3-Hydroxy-3-methylglutaryl coenzyme a reductase and isoprenylation inhibitors induce apoptosis of vascular smooth muscle cells in culture.
Guijarro C; Blanco-Colio LM; Ortego M; Alonso C; Ortiz A; Plaza JJ; Díaz C; Hernández G; Egido J
Circ Res; 1998 Sep; 83(5):490-500. PubMed ID: 9734471
[TBL] [Abstract][Full Text] [Related]
20. Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells.
Wong DH; Villanueva JA; Cress AB; Sokalska A; Ortega I; Duleba AJ
Fertil Steril; 2011 Nov; 96(5):1252-8. PubMed ID: 21907337
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]