347 related articles for article (PubMed ID: 10758003)
1. Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
McMillan FM; Cahoon M; White A; Hedstrom L; Petsko GA; Ringe D
Biochemistry; 2000 Apr; 39(15):4533-42. PubMed ID: 10758003
[TBL] [Abstract][Full Text] [Related]
2. Expression, purification, and characterization of inosine 5'-monophosphate dehydrogenase from Borrelia burgdorferi.
Zhou X; Cahoon M; Rosa P; Hedstrom L
J Biol Chem; 1997 Aug; 272(35):21977-81. PubMed ID: 9268334
[TBL] [Abstract][Full Text] [Related]
3. Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
Makowska-Grzyska M; Kim Y; Wu R; Wilton R; Gollapalli DR; Wang XK; Zhang R; Jedrzejczak R; Mack JC; Maltseva N; Mulligan R; Binkowski TA; Gornicki P; Kuhn ML; Anderson WF; Hedstrom L; Joachimiak A
Biochemistry; 2012 Aug; 51(31):6148-63. PubMed ID: 22788966
[TBL] [Abstract][Full Text] [Related]
4. Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis.
Gan L; Petsko GA; Hedstrom L
Biochemistry; 2002 Nov; 41(44):13309-17. PubMed ID: 12403633
[TBL] [Abstract][Full Text] [Related]
5. IMP dehydrogenase : structural aspects of inhibitor binding.
Goldstein BM; Colby TD
Curr Med Chem; 1999 Jul; 6(7):519-36. PubMed ID: 10390598
[TBL] [Abstract][Full Text] [Related]
6. Crystal structure of Tritrichomonas foetus inosine monophosphate dehydrogenase in complex with the inhibitor ribavirin monophosphate reveals a catalysis-dependent ion-binding site.
Prosise GL; Wu JZ; Luecke H
J Biol Chem; 2002 Dec; 277(52):50654-9. PubMed ID: 12235158
[TBL] [Abstract][Full Text] [Related]
7. Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
Prosise GL; Luecke H
J Mol Biol; 2003 Feb; 326(2):517-27. PubMed ID: 12559919
[TBL] [Abstract][Full Text] [Related]
8. Tritrichomonas foetus: a strategy for structure-based inhibitor design of a protozoan inosine-5'-monophosphate dehydrogenase.
Luecke H; Prosise GL; Whitby FG
Exp Parasitol; 1997 Nov; 87(3):203-11. PubMed ID: 9371085
[TBL] [Abstract][Full Text] [Related]
9. IMP dehydrogenase: mechanism of action and inhibition.
Hedstrom L
Curr Med Chem; 1999 Jul; 6(7):545-60. PubMed ID: 10390600
[TBL] [Abstract][Full Text] [Related]
10. Kinetic mechanism of human inosine 5'-monophosphate dehydrogenase type II: random addition of substrates and ordered release of products.
Wang W; Hedstrom L
Biochemistry; 1997 Jul; 36(28):8479-83. PubMed ID: 9214292
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.
Colby TD; Vanderveen K; Strickler MD; Markham GD; Goldstein BM
Proc Natl Acad Sci U S A; 1999 Mar; 96(7):3531-6. PubMed ID: 10097070
[TBL] [Abstract][Full Text] [Related]
12. Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid.
Sintchak MD; Fleming MA; Futer O; Raybuck SA; Chambers SP; Caron PR; Murcko MA; Wilson KP
Cell; 1996 Jun; 85(6):921-30. PubMed ID: 8681386
[TBL] [Abstract][Full Text] [Related]
13. Inactivation of inosine 5'-monophosphate dehydrogenase by the antiviral agent 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide 5'-monophosphate.
Wang W; Papov VV; Minakawa N; Matsuda A; Biemann K; Hedstrom L
Biochemistry; 1996 Jan; 35(1):95-101. PubMed ID: 8555204
[TBL] [Abstract][Full Text] [Related]
14. Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex.
Whitby FG; Luecke H; Kuhn P; Somoza JR; Huete-Perez JA; Phillips JD; Hill CP; Fletterick RJ; Wang CC
Biochemistry; 1997 Sep; 36(35):10666-74. PubMed ID: 9271497
[TBL] [Abstract][Full Text] [Related]
15. Use of Inosine Monophosphate Dehydrogenase Activity Assay to Determine the Specificity of PARP-1 Inhibitors.
Anthony S; Peterson JR; Ji Y
Methods Mol Biol; 2017; 1608():337-342. PubMed ID: 28695520
[TBL] [Abstract][Full Text] [Related]
16. The structure of inosine 5'-monophosphate dehydrogenase and the design of novel inhibitors.
Sintchak MD; Nimmesgern E
Immunopharmacology; 2000 May; 47(2-3):163-84. PubMed ID: 10878288
[TBL] [Abstract][Full Text] [Related]
17. Kinetic mechanism of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase.
Digits JA; Hedstrom L
Biochemistry; 1999 Feb; 38(8):2295-306. PubMed ID: 10029522
[TBL] [Abstract][Full Text] [Related]
18. Mycophenolic acid and thiazole adenine dinucleotide inhibition of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: implications on enzyme mechanism.
Hedstrom L; Wang CC
Biochemistry; 1990 Jan; 29(4):849-54. PubMed ID: 1971185
[TBL] [Abstract][Full Text] [Related]
19. Human IMP dehydrogenase catalyzes the dehalogenation of 2-fluoro- and 2-chloroinosine 5'-monophosphate in the absence of NAD.
Antonino LC; Wu JC
Biochemistry; 1994 Feb; 33(7):1753-9. PubMed ID: 7906542
[TBL] [Abstract][Full Text] [Related]
20. Acid-base catalysis in the chemical mechanism of inosine monophosphate dehydrogenase.
Markham GD; Bock CL; Schalk-Hihi C
Biochemistry; 1999 Apr; 38(14):4433-40. PubMed ID: 10194364
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
