BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 10758785)

  • 1. DNA sequence-recognizing properties of minor groove alkylating agents. Effects of the replacement of N-methylpyrrole by an N-methylimidazole on tallimustine and its own homologue.
    Baraldi PG; Romagnoli R; Spalluto G; Cozzi P; Mongelli N; Bianchi N; Gambari R
    Arzneimittelforschung; 2000 Mar; 50(3):309-15. PubMed ID: 10758785
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PNU 157977: a new potent antitumour agent exhibiting low in vivo toxicity in mice injected with L1210 leukaemia cells.
    Baraldi PG; Balboni G; Romagnoli R; Spalluto G; Cozzi P; Geroni C; Mongelli N; Rutigliano C; Bianchi N; Gambari R
    Anticancer Drug Des; 1999 Feb; 14(1):71-6. PubMed ID: 10363029
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA-Directed alkylating agents. 7. Synthesis, DNA interaction, and antitumor activity of bis(hydroxymethyl)- and bis(carbamate)-substituted pyrrolizines and imidazoles.
    Atwell GJ; Fan JY; Tan K; Denny WA
    J Med Chem; 1998 Nov; 41(24):4744-54. PubMed ID: 9822545
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The alkylating antitumor drug tallimustine does not induce DNA repair.
    Rossi R; Montecucco A; Capolongo L; Mezzina M; Chevallier-Lagente O; Sarasin A; Ciarrocchi G
    Anticancer Res; 1996; 16(6B):3779-83. PubMed ID: 9042257
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytotoxic alpha-halogenoacrylic derivatives of distamycin A and congeners.
    Beria I; Baraldi PG; Cozzi P; Caldarelli M; Geroni C; Marchini S; Mongelli N; Romagnoli R
    J Med Chem; 2004 May; 47(10):2611-23. PubMed ID: 15115402
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequence-specific DNA alkylation of novel tallimustine derivatives.
    Marchini S; Cozzi P; Beria I; Geroni C; Capolongo L; D'Incalci M; Broggini M
    Anticancer Drug Des; 1998 Apr; 13(3):193-205. PubMed ID: 9595033
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycin.
    Wyatt MD; Garbiras BJ; Haskell MK; Lee M; Souhami RL; Hartley JA
    Anticancer Drug Des; 1994 Dec; 9(6):511-25. PubMed ID: 7880376
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, DNA binding, cytotoxicity and sequence specificity of a series of imidazole-containing analogs of the benzoic acid mustard distamycin derivative tallimustine containing an alkylating group at the C-terminus.
    Brooks N; Lee M; Wright SR; Woo S; Centioni S; Hartley JA
    Anticancer Drug Des; 1997 Oct; 12(7):591-606. PubMed ID: 9365504
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combinatorial identification of a novel consensus sequence for the covalent DNA-binding polyamide tallimustine.
    Sunavala-Dossabhoy G; Van Dyke MW
    Biochemistry; 2005 Feb; 44(7):2510-22. PubMed ID: 15709763
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Benzoyl and cinnamoyl nitrogen mustard derivatives of benzoheterocyclic analogues of the tallimustine: synthesis and antitumour activity.
    Baraldi PG; Romagnoli R; Giovanna Pavani M; del Carmen Nunez M; Bingham JP; Hartley JA
    Bioorg Med Chem; 2002 May; 10(5):1611-8. PubMed ID: 11886822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition.
    Shinohara K; Bando T; Sugiyama H
    Anticancer Drugs; 2010 Mar; 21(3):228-42. PubMed ID: 20038830
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological properties of highly sequence-specific-alkylating N-methylpyrrole-N-methylimidazole polyamide conjugates.
    Kashiwazaki G; Bando T; Yoshidome T; Masui S; Takagaki T; Hashiya K; Pandian GN; Yasuoka J; Akiyoshi K; Sugiyama H
    J Med Chem; 2012 Mar; 55(5):2057-66. PubMed ID: 22309169
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hybrid molecules between distamycin A and active moieties of antitumor agents.
    Baraldi PG; Preti D; Fruttarolo F; Tabrizi MA; Romagnoli R
    Bioorg Med Chem; 2007 Jan; 15(1):17-35. PubMed ID: 17081759
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies.
    Baraldi PG; Beria I; Cozzi P; Geroni C; Espinosa A; Gallo MA; Entrena A; Bingham JP; Hartley JA; Romagnoli R
    Bioorg Med Chem; 2004 Jul; 12(14):3911-21. PubMed ID: 15210158
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders.
    Baraldi PG; Balboni G; Pavani MG; Spalluto G; Tabrizi MA; Clercq ED; Balzarini J; Bando T; Sugiyama H; Romagnoli R
    J Med Chem; 2001 Aug; 44(16):2536-43. PubMed ID: 11472207
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new class of cytotoxic DNA minor groove binders: alpha-halogenoacrylic derivatives of pyrrolecarbamoyl oligomers.
    Cozzi P
    Farmaco; 2001; 56(1-2):57-65. PubMed ID: 11347968
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytotoxic and antitumor activity of MEN 10710, a novel alkylating derivative of distamycin.
    Bigioni M; Salvatore C; Palma C; Manzini S; Animati F; Lombardi P; Pratesi G; Supino R; Zunino F
    Anticancer Drugs; 1997 Oct; 8(9):845-52. PubMed ID: 9402311
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genotoxic, cytostatic, antineoplastic and apoptotic effects of newly synthesized antitumour steroidal esters.
    Karapidaki I; Bakopoulou A; Papageorgiou A; Iakovidou Z; Mioglou E; Nikolaropoulos S; Mourelatos D; Lialiaris T
    Mutat Res; 2009 Apr; 675(1-2):51-9. PubMed ID: 19386248
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combination of the new minor groove alkylator tallimustine and melphalan.
    Tagliabue G; Filippini C; Ubezio P; D'Incalci M
    Eur J Cancer; 1997 Feb; 33(2):284-7. PubMed ID: 9135501
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationship of a series of C-terminus modified aminoalkyl, diaminoalkyl- and anilino-containing analogues of the benzoic acid mustard distamycin derivative tallimustine: synthesis, DNA binding and cytotoxicity studies.
    Brooks N; Hartley JA; Simpson JE; Wright SR; Woo S; Centioni S; Fontaine MD; McIntyre TE; Lee M
    Bioorg Med Chem; 1997 Aug; 5(8):1497-507. PubMed ID: 9313856
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.