BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

367 related articles for article (PubMed ID: 10759686)

  • 21. In vitro metabolism of quinidine: the (3S)-3-hydroxylation of quinidine is a specific marker reaction for cytochrome P-4503A4 activity in human liver microsomes.
    Nielsen TL; Rasmussen BB; Flinois JP; Beaune P; Brosen K
    J Pharmacol Exp Ther; 1999 Apr; 289(1):31-7. PubMed ID: 10086984
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Metabolism of thioridazine by microsomal monooxygenases: relative roles of P450 and flavin-containing monooxygenase.
    Blake BL; Rose RL; Mailman RB; Levi PE; Hodgson E
    Xenobiotica; 1995 Apr; 25(4):377-93. PubMed ID: 7645304
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Nefiracetam metabolism by human liver microsomes: role of cytochrome P450 3A4 and cytochrome P450 1A2 in 5-hydroxynefiracetam formation.
    Fujimaki Y; Arai N; Nakazawa T; Fujimaki M
    J Pharm Pharmacol; 2001 Jun; 53(6):795-804. PubMed ID: 11428655
    [TBL] [Abstract][Full Text] [Related]  

  • 24. In vitro metabolism of clindamycin in human liver and intestinal microsomes.
    Wynalda MA; Hutzler JM; Koets MD; Podoll T; Wienkers LC
    Drug Metab Dispos; 2003 Jul; 31(7):878-87. PubMed ID: 12814964
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of FMO3 polymorphisms on enzyme activity.
    Störmer E; Roots I; Brockmöller J
    Br J Clin Pharmacol; 2000 Dec; 50(6):553-61. PubMed ID: 11136294
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4.
    Gallagher EP; Kunze KL; Stapleton PL; Eaton DL
    Toxicol Appl Pharmacol; 1996 Dec; 141(2):595-606. PubMed ID: 8975785
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Metabolism of diallyl disulfide by human liver microsomal cytochromes P-450 and flavin-containing monooxygenases.
    Teyssier C; Guenot L; Suschetet M; Siess MH
    Drug Metab Dispos; 1999 Jul; 27(7):835-41. PubMed ID: 10383929
    [TBL] [Abstract][Full Text] [Related]  

  • 28. In vitro evaluation of potential in vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms.
    Lang DH; Rettie AE
    Br J Clin Pharmacol; 2000 Oct; 50(4):311-4. PubMed ID: 11012553
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A; Satoh H; Thomas PE; Bush E; Moore D
    Drug Metab Dispos; 1996 Sep; 24(9):940-7. PubMed ID: 8886602
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Roles of FMO and CYP450 in the metabolism in human liver microsomes of S-methyl-N,N-diethyldithiocarbamate, a disulfiram metabolite.
    Pike MG; Martin YN; Mays DC; Benson LM; Naylor S; Lipsky JJ
    Alcohol Clin Exp Res; 1999 Jul; 23(7):1173-9. PubMed ID: 10443982
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.
    Chung WG; Park CS; Roh HK; Lee WK; Cha YN
    Jpn J Pharmacol; 2000 Oct; 84(2):213-20. PubMed ID: 11128045
    [TBL] [Abstract][Full Text] [Related]  

  • 32. S-oxidation of S-methyl-esonarimod by flavin-containing monooxygenases in human liver microsomes.
    Ohmi N; Yoshida H; Endo H; Hasegawa M; Akimoto M; Higuchi S
    Xenobiotica; 2003 Dec; 33(12):1221-31. PubMed ID: 14742144
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.
    Hyland R; Roe EG; Jones BC; Smith DA
    Br J Clin Pharmacol; 2001 Mar; 51(3):239-48. PubMed ID: 11298070
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
    Casabar RC; Wallace AD; Hodgson E; Rose RL
    Drug Metab Dispos; 2006 Oct; 34(10):1779-85. PubMed ID: 16855053
    [TBL] [Abstract][Full Text] [Related]  

  • 35. What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?
    Wagmann L; Meyer MR; Maurer HH
    Toxicol Lett; 2016 Sep; 258():55-70. PubMed ID: 27320963
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Identification of human drug-metabolizing enzymes involved in the metabolism of SNI-2011.
    Washio T; Arisawa H; Kohsaka K; Yasuda H
    Biol Pharm Bull; 2001 Nov; 24(11):1263-6. PubMed ID: 11725960
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Assessment of the main metabolism pathways for the flukicidal compound triclabendazole in sheep.
    Virkel G; Lifschitz A; Sallovitz J; Pis A; Lanusse C
    J Vet Pharmacol Ther; 2006 Jun; 29(3):213-23. PubMed ID: 16669866
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification of human cytochrome P450 isoforms involved in the metabolism of brotizolam.
    Senda C; Kishimoto W; Sakai K; Nagakura A; Igarashi T
    Xenobiotica; 1997 Sep; 27(9):913-22. PubMed ID: 9381732
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes.
    Zhang WV; D'Esposito F; Edwards RJ; Ramzan I; Murray M
    Drug Metab Dispos; 2008 Dec; 36(12):2547-55. PubMed ID: 18809730
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor.
    Chiba M; Hensleigh M; Nishime JA; Balani SK; Lin JH
    Drug Metab Dispos; 1996 Mar; 24(3):307-14. PubMed ID: 8820421
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.