184 related articles for article (PubMed ID: 10760475)
1. Function of human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase in androgen metabolism.
He XY; Merz G; Yang YZ; Pullakart R; Mehta P; Schulz H; Yang SY
Biochim Biophys Acta; 2000 Apr; 1484(2-3):267-77. PubMed ID: 10760475
[TBL] [Abstract][Full Text] [Related]
2. Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease.
Bauman DR; Steckelbroeck S; Williams MV; Peehl DM; Penning TM
Mol Endocrinol; 2006 Feb; 20(2):444-58. PubMed ID: 16179381
[TBL] [Abstract][Full Text] [Related]
3. Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men.
Blouin K; Richard C; Brochu G; Hould FS; Lebel S; Marceau S; Biron S; Luu-The V; Tchernof A
J Endocrinol; 2006 Dec; 191(3):637-49. PubMed ID: 17170221
[TBL] [Abstract][Full Text] [Related]
4. Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.
Rizner TL; Lin HK; Peehl DM; Steckelbroeck S; Bauman DR; Penning TM
Endocrinology; 2003 Jul; 144(7):2922-32. PubMed ID: 12810547
[TBL] [Abstract][Full Text] [Related]
5. Role of human type 3 3alpha-hydroxysteroid dehydrogenase (AKR1C2) in androgen metabolism of prostate cancer cells.
Rizner TL; Lin HK; Penning TM
Chem Biol Interact; 2003 Feb; 143-144():401-9. PubMed ID: 12604227
[TBL] [Abstract][Full Text] [Related]
6. Oxidative 3alpha-hydroxysteroid dehydrogenase activity of human type 10 17beta-hydroxysteroid dehydrogenase.
He XY; Yang YZ; Peehl DM; Lauderdale A; Schulz H; Yang SY
J Steroid Biochem Mol Biol; 2003 Nov; 87(2-3):191-8. PubMed ID: 14672739
[TBL] [Abstract][Full Text] [Related]
7. Intrinsic alcohol dehydrogenase and hydroxysteroid dehydrogenase activities of human mitochondrial short-chain L-3-hydroxyacyl-CoA dehydrogenase.
He XY; Yang YZ; Schulz H; Yang SY
Biochem J; 2000 Jan; 345 Pt 1(Pt 1):139-43. PubMed ID: 10600649
[TBL] [Abstract][Full Text] [Related]
8. Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution.
Lin HK; Jez JM; Schlegel BP; Peehl DM; Pachter JA; Penning TM
Mol Endocrinol; 1997 Dec; 11(13):1971-84. PubMed ID: 9415401
[TBL] [Abstract][Full Text] [Related]
9. 5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: implication of androgen-independent prostate cancer progression.
Yang Q; Titus MA; Fung KM; Lin HK
J Cell Biochem; 2008 Aug; 104(5):1612-24. PubMed ID: 18320593
[TBL] [Abstract][Full Text] [Related]
10. Androgen formation and metabolism in the pulmonary epithelial cell line A549: expression of 17beta-hydroxysteroid dehydrogenase type 5 and 3alpha-hydroxysteroid dehydrogenase type 3.
Provost PR; Blomquist CH; Godin C; Huang XF; Flamand N; Luu-The V; Nadeau D; Tremblay Y
Endocrinology; 2000 Aug; 141(8):2786-94. PubMed ID: 10919264
[TBL] [Abstract][Full Text] [Related]
11. Partitioning of 5alpha-dihydrotestosterone and 5alpha-androstane-3alpha, 17beta-diol activated pathways for stimulating human prostate cancer LNCaP cell proliferation.
Nunlist EH; Dozmorov I; Tang Y; Cowan R; Centola M; Lin HK
J Steroid Biochem Mol Biol; 2004 Jul; 91(3):157-70. PubMed ID: 15276623
[TBL] [Abstract][Full Text] [Related]
12. Formation of 5α-dihydrotestosterone from 5α-androstane-3α,17β-diol in prostate cancer LAPC-4 cells - Identifying inhibitors of non-classical pathways producing the most potent androgen.
Boutin S; Roy J; Maltais R; Poirier D
Bioorg Med Chem Lett; 2020 Jan; 30(2):126783. PubMed ID: 31753699
[TBL] [Abstract][Full Text] [Related]
13. Dissection of the physiological interconversion of 5alpha-DHT and 3alpha-diol by rat 3alpha-HSD via transient kinetics shows that the chemical step is rate-determining: effect of mutating cofactor and substrate-binding pocket residues on catalysis.
Heredia VV; Penning TM
Biochemistry; 2004 Sep; 43(38):12028-37. PubMed ID: 15379543
[TBL] [Abstract][Full Text] [Related]
14. Roles of Mitochondrial 17β-Hydroxysteroid Dehydrogenase Type 10 in Alzheimer's Disease.
He XY; Isaacs C; Yang SY
J Alzheimers Dis; 2018; 62(2):665-673. PubMed ID: 29480196
[TBL] [Abstract][Full Text] [Related]
15. CYP7B1-mediated metabolism of 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol): a novel pathway for potential regulation of the cellular levels of androgens and neurosteroids.
Pettersson H; Lundqvist J; Oliw E; Norlin M
Biochim Biophys Acta; 2009 Dec; 1791(12):1206-15. PubMed ID: 19732851
[TBL] [Abstract][Full Text] [Related]
16. Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
Penning TM; Burczynski ME; Jez JM; Hung CF; Lin HK; Ma H; Moore M; Palackal N; Ratnam K
Biochem J; 2000 Oct; 351(Pt 1):67-77. PubMed ID: 10998348
[TBL] [Abstract][Full Text] [Related]
17. Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.
Hardy DO; Ge RS; Catterall JF; Hou YT; Penning TM; Hardy MP
Endocrinology; 2000 May; 141(5):1608-17. PubMed ID: 10803568
[TBL] [Abstract][Full Text] [Related]
18. Steroid 5alpha-reductases and 3alpha-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism.
Jin Y; Penning TM
Best Pract Res Clin Endocrinol Metab; 2001 Mar; 15(1):79-94. PubMed ID: 11469812
[TBL] [Abstract][Full Text] [Related]
19. Human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase is a single-domain multifunctional enzyme. Characterization of a novel 17beta-hydroxysteroid dehydrogenase.
He XY; Merz G; Mehta P; Schulz H; Yang SY
J Biol Chem; 1999 May; 274(21):15014-9. PubMed ID: 10329704
[TBL] [Abstract][Full Text] [Related]
20. Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action.
Steckelbroeck S; Jin Y; Gopishetty S; Oyesanmi B; Penning TM
J Biol Chem; 2004 Mar; 279(11):10784-95. PubMed ID: 14672942
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]