224 related articles for article (PubMed ID: 10761907)
1. Peptide exosite inhibitors of factor VIIa as anticoagulants.
Dennis MS; Eigenbrot C; Skelton NJ; Ultsch MH; Santell L; Dwyer MA; O'Connell MP; Lazarus RA
Nature; 2000 Mar; 404(6777):465-70. PubMed ID: 10761907
[TBL] [Abstract][Full Text] [Related]
2. Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant.
Zhang E; St Charles R; Tulinsky A
J Mol Biol; 1999 Feb; 285(5):2089-104. PubMed ID: 9925787
[TBL] [Abstract][Full Text] [Related]
3. Selective attenuation of the extrinsic limb of the tissue factor-driven coagulation protease cascade by occupancy of a novel peptidyl docking site on tissue factor.
Huang H; Norledge BV; Liu C; Olson AJ; Edgington TS
Biochemistry; 2003 Sep; 42(36):10619-26. PubMed ID: 12962485
[TBL] [Abstract][Full Text] [Related]
4. The quest for Factor VIIa exosite inhibitors.
Amour A; Hutchinson J; Ruiz Avendaño AM; Ratcliffe S; Alvarez E; Martin J; Toomey JR; Senger S; Wolfendale M; Mooney C
Biochem Soc Trans; 2007 Jun; 35(Pt 3):555-8. PubMed ID: 17511650
[TBL] [Abstract][Full Text] [Related]
5. The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.
Banner DW; D'Arcy A; Chène C; Winkler FK; Guha A; Konigsberg WH; Nemerson Y; Kirchhofer D
Nature; 1996 Mar; 380(6569):41-6. PubMed ID: 8598903
[TBL] [Abstract][Full Text] [Related]
6. Design, parallel synthesis, and crystal structures of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.
Parlow JJ; Case BL; Dice TA; Fenton RL; Hayes MJ; Jones DE; Neumann WL; Wood RS; Lachance RM; Girard TJ; Nicholson NS; Clare M; Stegeman RA; Stevens AM; Stallings WC; Kurumbail RG; South MS
J Med Chem; 2003 Sep; 46(19):4050-62. PubMed ID: 12954058
[TBL] [Abstract][Full Text] [Related]
7. Structure-based design of P3 moieties in the peptide mimetic factor VIIa inhibitor.
Kadono S; Sakamoto A; Kikuchi Y; Oh-eda M; Yabuta N; Yoshihashi K; Kitazawa T; Suzuki T; Koga T; Hattori K; Shiraishi T; Haramura M; Kodama H; Ono Y; Esaki T; Sato H; Watanabe Y; Itoh S; Ohta M; Kozono T
Biochem Biophys Res Commun; 2005 Feb; 327(2):589-96. PubMed ID: 15629154
[TBL] [Abstract][Full Text] [Related]
8. A novel exosite on coagulation factor VIIa and its molecular interactions with a new class of peptide inhibitors.
Roberge M; Santell L; Dennis MS; Eigenbrot C; Dwyer MA; Lazarus RA
Biochemistry; 2001 Aug; 40(32):9522-31. PubMed ID: 11583151
[TBL] [Abstract][Full Text] [Related]
9. Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors.
Zbinden KG; Obst-Sander U; Hilpert K; Kühne H; Banner DW; Böhm HJ; Stahl M; Ackermann J; Alig L; Weber L; Wessel HP; Riederer MA; Tschopp TB; Lavé T
Bioorg Med Chem Lett; 2005 Dec; 15(23):5344-52. PubMed ID: 16213138
[TBL] [Abstract][Full Text] [Related]
10. Conformational transitions in factor VIIa: can we stabilize the inactive form of the enzyme?
De CR
Thromb Haemost; 2002 Jan; 87(1):4-6. PubMed ID: 11848455
[No Abstract] [Full Text] [Related]
11. Engineering exosite peptides for complete inhibition of factor VIIa using a protease switch with substrate phage.
Maun HR; Eigenbrot C; Lazarus RA
J Biol Chem; 2003 Jun; 278(24):21823-30. PubMed ID: 12657647
[TBL] [Abstract][Full Text] [Related]
12. Similar molecular interactions of factor VII and factor VIIa with the tissue factor region that allosterically regulates enzyme activity.
Kelley RF; Yang J; Eigenbrot C; Moran P; Peek M; Lipari MT; Kirchhofer D
Biochemistry; 2004 Feb; 43(5):1223-9. PubMed ID: 14756558
[TBL] [Abstract][Full Text] [Related]
13. Inhibitors of factor VIIa affect the interface between the protease domain and tissue factor.
Carlsson K; Persson E; Carlsson U; Svensson M
Biochem Biophys Res Commun; 2006 Oct; 349(3):1111-6. PubMed ID: 16970919
[TBL] [Abstract][Full Text] [Related]
14. Novel interactions of large P3 moiety and small P4 moiety in the binding of the peptide mimetic factor VIIa inhibitor.
Kadono S; Sakamoto A; Kikuchi Y; Oh-Eda M; Yabuta N; Yoshihashi K; Kitazawa T; Suzuki T; Koga T; Hattori K; Shiraishi T; Haramura M; Kodama H; Ono Y; Esaki T; Sato H; Watanabe Y; Itoh S; Ohta M; Kozono T
Biochem Biophys Res Commun; 2005 Jan; 326(4):859-65. PubMed ID: 15607748
[TBL] [Abstract][Full Text] [Related]
15. Discovery of a novel, potent, and specific family of factor Xa inhibitors via combinatorial chemistry.
Ostrem JA; al-Obeidi F; Safar P; Safarova A; Stringer SK; Patek M; Cross MT; Spoonamore J; LoCascio JC; Kasireddy P; Thorpe DS; Sepetov N; Lebl M; Wildgoose P; Strop P
Biochemistry; 1998 Jan; 37(4):1053-9. PubMed ID: 9454596
[TBL] [Abstract][Full Text] [Related]
16. The solution structure of human coagulation factor VIIa in its complex with tissue factor is similar to free factor VIIa: a study of a heterodimeric receptor-ligand complex by X-ray and neutron scattering and computational modeling.
Ashton AW; Boehm MK; Johnson DJ; Kemball-Cook G; Perkins SJ
Biochemistry; 1998 Jun; 37(22):8208-17. PubMed ID: 9609717
[TBL] [Abstract][Full Text] [Related]
17. Influence of cofactor binding and active site occupancy on the conformation of the macromolecular substrate exosite of factor VIIa.
Dickinson CD; Shobe J; Ruf W
J Mol Biol; 1998 Apr; 277(4):959-71. PubMed ID: 9545384
[TBL] [Abstract][Full Text] [Related]
18. Crystal structure of human factor VIIa/tissue factor in complex with peptide mimetic inhibitor.
Kadono S; Sakamoto A; Kikuchi Y; Oh-eda M; Yabuta N; Koga T; Hattori K; Shiraishi T; Haramura M; Kodama H; Esaki T; Sato H; Watanabe Y; Itoh S; Ohta M; Kozono T
Biochem Biophys Res Commun; 2004 Nov; 324(4):1227-33. PubMed ID: 15504346
[TBL] [Abstract][Full Text] [Related]
19. Selection and characterization of a new class of peptide exosite inhibitors of coagulation factor VIIa.
Dennis MS; Roberge M; Quan C; Lazarus RA
Biochemistry; 2001 Aug; 40(32):9513-21. PubMed ID: 11583150
[TBL] [Abstract][Full Text] [Related]
20. Regulation of the catalytic function of coagulation factor VIIa by a conformational linkage of surface residue Glu 154 to the active site.
Shobe J; Dickinson CD; Ruf W
Biochemistry; 1999 Mar; 38(9):2745-51. PubMed ID: 10052945
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]