223 related articles for article (PubMed ID: 10761907)
21. Probing the S2 site of factor VIIa to generate potent and selective inhibitors: the structure of BCX-3607 in complex with tissue factor-factor VIIa.
Krishnan R; Kotian PL; Chand P; Bantia S; Rowland S; Babu YS
Acta Crystallogr D Biol Crystallogr; 2007 Jun; 63(Pt 6):689-97. PubMed ID: 17505107
[TBL] [Abstract][Full Text] [Related]
22. Kinetics of the inhibition of tissue factor-factor VIIa by tissue factor pathway inhibitor.
Lindhout T; Franssen J; Willems G
Thromb Haemost; 1995 Sep; 74(3):910-5. PubMed ID: 8571320
[TBL] [Abstract][Full Text] [Related]
23. Fusion of two distinct peptide exosite inhibitors of Factor VIIa.
Roberge M; Peek M; Kirchhofer D; Dennis MS; Lazarus RA
Biochem J; 2002 Apr; 363(Pt 2):387-93. PubMed ID: 11931669
[TBL] [Abstract][Full Text] [Related]
24. Optimization of a coagulation factor VIIa inhibitor found in factor Xa inhibitor library.
Sagi K; Fujita K; Sugiki M; Takahashi M; Takehana S; Tashiro K; Kayahara T; Yamanashi M; Fukuda Y; Oono S; Okajima A; Iwata S; Shoji M; Sakurai K
Bioorg Med Chem; 2005 Mar; 13(5):1487-96. PubMed ID: 15698764
[TBL] [Abstract][Full Text] [Related]
25. Intermolecular interactions and characterization of the novel factor Xa exosite involved in macromolecular recognition and inhibition: crystal structure of human Gla-domainless factor Xa complexed with the anticoagulant protein NAPc2 from the hematophagous nematode Ancylostoma caninum.
Murakami MT; Rios-Steiner J; Weaver SE; Tulinsky A; Geiger JH; Arni RK
J Mol Biol; 2007 Feb; 366(2):602-10. PubMed ID: 17173931
[TBL] [Abstract][Full Text] [Related]
26. Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores.
Kotian PL; Krishnan R; Rowland S; El-Kattan Y; Saini SK; Upshaw R; Bantia S; Arnold S; Babu YS; Chand P
Bioorg Med Chem; 2009 Jun; 17(11):3934-58. PubMed ID: 19409795
[TBL] [Abstract][Full Text] [Related]
27. Prevention of beta strand movement into a zymogen-like position does not confer higher activity to coagulation factor VIIa.
Olsen OH; Nielsen PF; Persson E
Biochemistry; 2004 Nov; 43(44):14096-103. PubMed ID: 15518559
[TBL] [Abstract][Full Text] [Related]
28. Crystal structure of active site-inhibited human coagulation factor VIIa (des-Gla).
Kemball-Cook G; Johnson DJ; Tuddenham EG; Harlos K
J Struct Biol; 1999 Oct; 127(3):213-23. PubMed ID: 10544046
[TBL] [Abstract][Full Text] [Related]
29. Inhibitors of Factor VIIa/tissue factor.
Shirk RA; Vlasuk GP
Arterioscler Thromb Vasc Biol; 2007 Sep; 27(9):1895-900. PubMed ID: 17600222
[TBL] [Abstract][Full Text] [Related]
30. Polymer-assisted solution-phase library synthesis and crystal structure of alpha-ketothiazoles as tissue factor VIIa inhibitors.
Parlow JJ; Dice TA; Lachance RM; Girard TJ; Stevens AM; Stegeman RA; Stallings WC; Kurumbail RG; South MS
J Med Chem; 2003 Sep; 46(19):4043-9. PubMed ID: 12954057
[TBL] [Abstract][Full Text] [Related]
31. Current status on tissue factor activation of factor VIIa.
Persson E; Olsen OH
Thromb Res; 2010 Apr; 125 Suppl 1():S11-2. PubMed ID: 20153879
[TBL] [Abstract][Full Text] [Related]
32. The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex.
Kohrt JT; Filipski KJ; Cody WL; Cai C; Dudley DA; Van Huis CA; Willardsen JA; Rapundalo ST; Saiya-Cork K; Leadley RJ; Narasimhan L; Zhang E; Whitlow M; Adler M; McLean K; Chou YL; McKnight C; Arnaiz DO; Shaw KJ; Light DR; Edmunds JJ
Bioorg Med Chem Lett; 2005 Nov; 15(21):4752-6. PubMed ID: 16125385
[TBL] [Abstract][Full Text] [Related]
33. [Tissue factor pathway inhibitors].
Sierko E; Zawadzki RJ; Wojtukiewicz MZ
Pol Merkur Lekarski; 2002 Jul; 13(73):66-9. PubMed ID: 12362512
[TBL] [Abstract][Full Text] [Related]
34. Phospholipid regulates the activation of factor X by tissue factor/factor VIIa (TF/VIIa) via substrate and product interactions.
Hathcock JJ; Rusinova E; Gentry RD; Andree H; Nemerson Y
Biochemistry; 2005 Jun; 44(22):8187-97. PubMed ID: 15924438
[TBL] [Abstract][Full Text] [Related]
35. Factor VIIa inhibitors: target hopping in the serine protease family using X-ray structure determination.
Shiraishi T; Kadono S; Haramura M; Kodama H; Ono Y; Iikura H; Esaki T; Koga T; Hattori K; Watanabe Y; Sakamoto A; Yoshihashi K; Kitazawa T; Esaki K; Ohta M; Sato H; Kozono T
Bioorg Med Chem Lett; 2008 Aug; 18(16):4533-7. PubMed ID: 18674905
[TBL] [Abstract][Full Text] [Related]
36. Dose-dependent antithrombotic activity of an orally active tissue factor/factor VIIa inhibitor without concomitant enhancement of bleeding propensity.
Groebke Zbinden K; Banner DW; Hilpert K; Himber J; Lavé T; Riederer MA; Stahl M; Tschopp TB; Obst-Sander U
Bioorg Med Chem; 2006 Aug; 14(15):5357-69. PubMed ID: 16621574
[TBL] [Abstract][Full Text] [Related]
37. Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide.
Lu D; Fütterer K; Korolev S; Zheng X; Tan K; Waksman G; Sadler JE
J Mol Biol; 1999 Sep; 292(2):361-73. PubMed ID: 10493881
[TBL] [Abstract][Full Text] [Related]
38. Ancylostoma ceylanicum anticoagulant peptide-1: role of the predicted reactive site amino acid in mediating inhibition of coagulation factors Xa and VIIa.
Mieszczanek J; Harrison LM; Cappello M
Mol Biochem Parasitol; 2004 Sep; 137(1):151-9. PubMed ID: 15279961
[TBL] [Abstract][Full Text] [Related]
39. A cyclic pentapeptide derived from the second EGF-like domain of Factor VII is an inhibitor of tissue factor dependent coagulation and thrombus formation.
Orning L; Fischer PM; Hu CK; Agner E; Engebretsen M; Husbyn M; Petersen LB; Orvim U; Llinas M; Sakariassen KS
Thromb Haemost; 2002 Jan; 87(1):13-21. PubMed ID: 11848442
[TBL] [Abstract][Full Text] [Related]
40. Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor.
Pan B; Li B; Russell SJ; Tom JY; Cochran AG; Fairbrother WJ
J Mol Biol; 2002 Feb; 316(3):769-87. PubMed ID: 11866530
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
