BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 10764142)

  • 1. Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias.
    Frankel AE; McCubrey JA; Miller MS; Delatte S; Ramage J; Kiser M; Kucera GL; Alexander RL; Beran M; Tagge EP; Kreitman RJ; Hogge DE
    Leukemia; 2000 Apr; 14(4):576-85. PubMed ID: 10764142
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.
    Feuring-Buske M; Frankel AE; Alexander RL; Gerhard B; Hogge DE
    Cancer Res; 2002 Mar; 62(6):1730-6. PubMed ID: 11912147
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Malignant progenitors from patients with CD87+ acute myelogenous leukemia are sensitive to a diphtheria toxin-urokinase fusion protein.
    Frankel AE; Beran M; Hogge DE; Powell BL; Thorburn A; Chen YQ; Vallera DA
    Exp Hematol; 2002 Nov; 30(11):1316-23. PubMed ID: 12423685
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
    Frankel AE; Lilly M; Kreitman R; Hogge D; Beran M; Freedman MH; Emanuel PD; McLain C; Hall P; Tagge E; Berger M; Eaves C
    Blood; 1998 Dec; 92(11):4279-86. PubMed ID: 9834234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials.
    Urieto JO; Liu T; Black JH; Cohen KA; Hall PD; Willingham MC; Pennell LK; Hogge DE; Kreitman RJ; Frankel AE
    Protein Expr Purif; 2004 Jan; 33(1):123-33. PubMed ID: 14680969
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Variant diphtheria toxin-interleukin-3 fusion proteins with increased receptor affinity have enhanced cytotoxicity against acute myeloid leukemia progenitors.
    Hogge DE; Yalcintepe L; Wong SH; Gerhard B; Frankel AE
    Clin Cancer Res; 2006 Feb; 12(4):1284-91. PubMed ID: 16489085
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High affinity interleukin-3 receptor expression on blasts from patients with acute myelogenous leukemia correlates with cytotoxicity of a diphtheria toxin/IL-3 fusion protein.
    Alexander RL; Ramage J; Kucera GL; Caligiuri MA; Frankel AE
    Leuk Res; 2001 Oct; 25(10):875-81. PubMed ID: 11532521
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Granulocyte-macrophage colony-stimulating factor receptor-targeted therapy of chemotherapy- and radiation-resistant human myeloid leukemias.
    Perentesis JP; Bendel AE; Shao Y; Warman B; Davies SM; Yang CH; Chandan-Langlie M; Waddick KG; Uckun FM
    Leuk Lymphoma; 1997 Apr; 25(3-4):247-56. PubMed ID: 9168435
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor.
    Bendel AE; Shao Y; Davies SM; Warman B; Yang CH; Waddick KG; Uckun FM; Perentesis JP
    Leuk Lymphoma; 1997 Apr; 25(3-4):257-70. PubMed ID: 9168436
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diphtheria toxin fused to variant interleukin-3 provides enhanced binding to the interleukin-3 receptor and more potent leukemia cell cytotoxicity.
    Liu TF; Urieto JO; Moore JE; Miller MS; Lowe AC; Thorburn A; Frankel AE
    Exp Hematol; 2004 Mar; 32(3):277-81. PubMed ID: 15003313
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro interleukin-3 binding to leukemia cells predicts cytotoxicity of a diphtheria toxin/IL-3 fusion protein.
    Alexander RL; Kucera GL; Klein B; Frankel AE
    Bioconjug Chem; 2000; 11(4):564-8. PubMed ID: 10898579
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of interleukin-3 receptor subunits on defined subpopulations of acute myeloid leukemia blasts predicts the cytotoxicity of diphtheria toxin interleukin-3 fusion protein against malignant progenitors that engraft in immunodeficient mice.
    Yalcintepe L; Frankel AE; Hogge DE
    Blood; 2006 Nov; 108(10):3530-7. PubMed ID: 16882709
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of diphtheria fusion proteins targeted to the human interleukin-3 receptor.
    Frankel AE; Ramage J; Kiser M; Alexander R; Kucera G; Miller MS
    Protein Eng; 2000 Aug; 13(8):575-81. PubMed ID: 10964987
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL3) prolongs disease-free survival of leukemic immunocompromised mice.
    Black JH; McCubrey JA; Willingham MC; Ramage J; Hogge DE; Frankel AE
    Leukemia; 2003 Jan; 17(1):155-9. PubMed ID: 12529673
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells.
    Terpstra W; Rozemuller H; Breems DA; Rombouts EJ; Prins A; FitzGerald DJ; Kreitman RJ; Wielenga JJ; Ploemacher RE; Löwenberg B; Hagenbeek A; Martens AC
    Blood; 1997 Nov; 90(9):3735-42. PubMed ID: 9345060
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein.
    Frankel AE; Hall PD; Burbage C; Vesely J; Willingham M; Bhalla K; Kreitman RJ
    Blood; 1997 Nov; 90(9):3654-61. PubMed ID: 9345050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein.
    Hogge DE; Willman CL; Kreitman RJ; Berger M; Hall PD; Kopecky KJ; McLain C; Tagge EP; Eaves CJ; Frankel AE
    Blood; 1998 Jul; 92(2):589-95. PubMed ID: 9657759
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acute-myeloid-leukemia-targeted toxins kill tumor cells by cell-type-specific mechanisms and synergize with TRAIL to allow manipulation of the extent and mechanism of tumor cell death.
    Horita H; Frankel AE; Thorburn A
    Leukemia; 2008 Mar; 22(3):652-5. PubMed ID: 17882279
    [No Abstract]   [Full Text] [Related]  

  • 19. Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia.
    Frankel AE; Powell BL; Hall PD; Case LD; Kreitman RJ
    Clin Cancer Res; 2002 May; 8(5):1004-13. PubMed ID: 12006512
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cell-specific modulation of drug resistance in acute myeloid leukemic blasts by diphtheria fusion toxin, DT388-GMCSF.
    Frankel AE; Hall PD; McLain C; Safa AR; Tagge EP; Kreitman RJ
    Bioconjug Chem; 1998; 9(4):490-6. PubMed ID: 9667951
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.