BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

289 related articles for article (PubMed ID: 10764742)

  • 1. A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1.
    Balendran A; Biondi RM; Cheung PC; Casamayor A; Deak M; Alessi DR
    J Biol Chem; 2000 Jul; 275(27):20806-13. PubMed ID: 10764742
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms.
    Balendran A; Hare GR; Kieloch A; Williams MR; Alessi DR
    FEBS Lett; 2000 Nov; 484(3):217-23. PubMed ID: 11078882
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1).
    Dettori R; Sonzogni S; Meyer L; Lopez-Garcia LA; Morrice NA; Zeuzem S; Engel M; Piiper A; Neimanis S; Frödin M; Biondi RM
    J Biol Chem; 2009 Oct; 284(44):30318-27. PubMed ID: 19723632
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vivo role of the phosphate groove of PDK1 defined by knockin mutation.
    Collins BJ; Deak M; Murray-Tait V; Storey KG; Alessi DR
    J Cell Sci; 2005 Nov; 118(Pt 21):5023-34. PubMed ID: 16219676
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of both PDK1 and the phosphorylation of PKC-zeta and -delta by a C-terminal PRK2 fragment.
    Hodgkinson CP; Sale GJ
    Biochemistry; 2002 Jan; 41(2):561-9. PubMed ID: 11781095
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA.
    Biondi RM; Cheung PC; Casamayor A; Deak M; Currie RA; Alessi DR
    EMBO J; 2000 Mar; 19(5):979-88. PubMed ID: 10698939
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252.
    Balendran A; Currie R; Armstrong CG; Avruch J; Alessi DR
    J Biol Chem; 1999 Dec; 274(52):37400-6. PubMed ID: 10601311
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells.
    Williams MR; Arthur JS; Balendran A; van der Kaay J; Poli V; Cohen P; Alessi DR
    Curr Biol; 2000 Apr; 10(8):439-48. PubMed ID: 10801415
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
    Balendran A; Casamayor A; Deak M; Paterson A; Gaffney P; Currie R; Downes CP; Alessi DR
    Curr Biol; 1999 Apr; 9(8):393-404. PubMed ID: 10226025
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of PDK2 activity against protein kinase B gamma.
    Hodgkinson CP; Sale EM; Sale GJ
    Biochemistry; 2002 Aug; 41(32):10351-9. PubMed ID: 12162751
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential roles of PDK1- and PDK2-phosphorylation sites in the yeast AGC kinases Ypk1, Pkc1 and Sch9.
    Roelants FM; Torrance PD; Thorner J
    Microbiology (Reading); 2004 Oct; 150(Pt 10):3289-304. PubMed ID: 15470109
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1.
    Wick MJ; Dong LQ; Riojas RA; Ramos FJ; Liu F
    J Biol Chem; 2000 Dec; 275(51):40400-6. PubMed ID: 11006271
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.
    Frödin M; Antal TL; Dümmler BA; Jensen CJ; Deak M; Gammeltoft S; Biondi RM
    EMBO J; 2002 Oct; 21(20):5396-407. PubMed ID: 12374740
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein kinase Cζ exhibits constitutive phosphorylation and phosphatidylinositol-3,4,5-triphosphate-independent regulation.
    Tobias IS; Kaulich M; Kim PK; Simon N; Jacinto E; Dowdy SF; King CC; Newton AC
    Biochem J; 2016 Feb; 473(4):509-23. PubMed ID: 26635352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1.
    Le Good JA; Ziegler WH; Parekh DB; Alessi DR; Cohen P; Parker PJ
    Science; 1998 Sep; 281(5385):2042-5. PubMed ID: 9748166
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1).
    Keshwani MM; von Daake S; Newton AC; Harris TK; Taylor SS
    J Biol Chem; 2011 Jul; 286(26):23552-8. PubMed ID: 21561857
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo.
    Lizcano JM; Deak M; Morrice N; Kieloch A; Hastie CJ; Dong L; Schutkowski M; Reimer U; Alessi DR
    J Biol Chem; 2002 Aug; 277(31):27839-49. PubMed ID: 12023960
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A chimeric mechanism for polyvalent trans-phosphorylation of PKA by PDK1.
    Romano RA; Kannan N; Kornev AP; Allison CJ; Taylor SS
    Protein Sci; 2009 Jul; 18(7):1486-97. PubMed ID: 19530248
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3.
    Sato S; Fujita N; Tsuruo T
    J Biol Chem; 2002 Oct; 277(42):39360-7. PubMed ID: 12177059
    [TBL] [Abstract][Full Text] [Related]  

  • 20. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
    García-Martínez JM; Alessi DR
    Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.