BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

387 related articles for article (PubMed ID: 10772658)

  • 1. A revised view of cardiac sodium channel "blockade" in the long-QT syndrome.
    Kambouris NG; Nuss HB; Johns DC; Marbán E; Tomaselli GF; Balser JR
    J Clin Invest; 2000 Apr; 105(8):1133-40. PubMed ID: 10772658
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phenotypic characterization of a novel long-QT syndrome mutation (R1623Q) in the cardiac sodium channel.
    Kambouris NG; Nuss HB; Johns DC; Tomaselli GF; Marban E; Balser JR
    Circulation; 1998 Feb; 97(7):640-4. PubMed ID: 9495298
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gating-dependent mechanisms for flecainide action in SCN5A-linked arrhythmia syndromes.
    Viswanathan PC; Bezzina CR; George AL; Roden DM; Wilde AA; Balser JR
    Circulation; 2001 Sep; 104(10):1200-5. PubMed ID: 11535580
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impaired stretch modulation in potentially lethal cardiac sodium channel mutants.
    Banderali U; Juranka PF; Clark RB; Giles WR; Morris CE
    Channels (Austin); 2010; 4(1):12-21. PubMed ID: 20090423
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lidocaine alters activation gating of cardiac Na channels.
    Hanck DA; Makielski JC; Sheets MF
    Pflugers Arch; 2000 Apr; 439(6):814-21. PubMed ID: 10784357
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective block of late currents in the DeltaKPQ Na(+) channel mutant by pilsicainide and lidocaine with distinct mechanisms.
    Ono K; Kaku T; Makita N; Kitabatake A; Arita M
    Mol Pharmacol; 2000 Feb; 57(2):392-400. PubMed ID: 10648650
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A de novo missense mutation of human cardiac Na+ channel exhibiting novel molecular mechanisms of long QT syndrome.
    Makita N; Shirai N; Nagashima M; Matsuoka R; Yamada Y; Tohse N; Kitabatake A
    FEBS Lett; 1998 Feb; 423(1):5-9. PubMed ID: 9506831
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of lidocaine block of late current in long Q-T mutant Na+ channels.
    Dumaine R; Kirsch GE
    Am J Physiol; 1998 Feb; 274(2):H477-87. PubMed ID: 9486250
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of action.
    Fredj S; Sampson KJ; Liu H; Kass RS
    Br J Pharmacol; 2006 May; 148(1):16-24. PubMed ID: 16520744
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: compound effects of hERG pore region mutation and SCN5A N-terminus variant.
    Lin MT; Wu MH; Chang CC; Chiu SN; Thériault O; Huang H; Christé G; Ficker E; Chahine M
    Heart Rhythm; 2008 Nov; 5(11):1567-74. PubMed ID: 18848812
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Congenital long-QT syndrome caused by a novel mutation in a conserved acidic domain of the cardiac Na+ channel.
    Wei J; Wang DW; Alings M; Fish F; Wathen M; Roden DM; George AL
    Circulation; 1999 Jun; 99(24):3165-71. PubMed ID: 10377081
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations.
    Liu H; Tateyama M; Clancy CE; Abriel H; Kass RS
    J Gen Physiol; 2002 Jul; 120(1):39-51. PubMed ID: 12084774
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome.
    Abriel H; Wehrens XH; Benhorin J; Kerem B; Kass RS
    Circulation; 2000 Aug; 102(8):921-5. PubMed ID: 10952963
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel mutation L619F in the cardiac Na+ channel SCN5A associated with long-QT syndrome (LQT3): a role for the I-II linker in inactivation gating.
    Wehrens XH; Rossenbacker T; Jongbloed RJ; Gewillig M; Heidbüchel H; Doevendans PA; Vos MA; Wellens HJ; Kass RS
    Hum Mutat; 2003 May; 21(5):552. PubMed ID: 12673799
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel mutation in SCN5A, delQKP 1507-1509, causing long QT syndrome: role of Q1507 residue in sodium channel inactivation.
    Keller DI; Acharfi S; Delacrétaz E; Benammar N; Rotter M; Pfammatter JP; Fressart V; Guicheney P; Chahine M
    J Mol Cell Cardiol; 2003 Dec; 35(12):1513-21. PubMed ID: 14654377
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels.
    Sheets MF; Hanck DA
    J Physiol; 2007 Jul; 582(Pt 1):317-34. PubMed ID: 17510181
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of human cardiac Na+ channel mutations in the congenital long QT syndrome.
    Wang DW; Yazawa K; George AL; Bennett PB
    Proc Natl Acad Sci U S A; 1996 Nov; 93(23):13200-5. PubMed ID: 8917568
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential modulation of late sodium current by protein kinase A in R1623Q mutant of LQT3.
    Tsurugi T; Nagatomo T; Abe H; Oginosawa Y; Takemasa H; Kohno R; Makita N; Makielski JC; Otsuji Y
    Life Sci; 2009 Mar; 84(11-12):380-7. PubMed ID: 19167409
    [TBL] [Abstract][Full Text] [Related]  

  • 19. State-dependent trapping of flecainide in the cardiac sodium channel.
    Ramos E; O'leary ME
    J Physiol; 2004 Oct; 560(Pt 1):37-49. PubMed ID: 15272045
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intrinsic mechanism of the enhanced rate-dependent QT shortening in the R1623Q mutant of the LQT3 syndrome.
    Oginosawa Y; Nagatomo T; Abe H; Makita N; Makielski JC; Nakashima Y
    Cardiovasc Res; 2005 Jan; 65(1):138-47. PubMed ID: 15621041
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.