BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1249 related articles for article (PubMed ID: 10773015)

  • 21. Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4.
    Feierman DE; Lasker JM
    Drug Metab Dispos; 1996 Sep; 24(9):932-9. PubMed ID: 8886601
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.
    Hamman MA; Thompson GA; Hall SD
    Biochem Pharmacol; 1997 Jul; 54(1):33-41. PubMed ID: 9296349
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone.
    Baldwin SJ; Clarke SE; Chenery RJ
    Br J Clin Pharmacol; 1999 Sep; 48(3):424-32. PubMed ID: 10510156
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes. Role of cytochrome P4502C and 3A subfamily members.
    Stearns RA; Chakravarty PK; Chen R; Chiu SH
    Drug Metab Dispos; 1995 Feb; 23(2):207-15. PubMed ID: 7736913
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Roles of two allelic variants (Arg144Cys and Ile359Leu) of cytochrome P4502C9 in the oxidation of tolbutamide and warfarin by human liver microsomes.
    Yamazaki H; Inoue K; Shimada T
    Xenobiotica; 1998 Feb; 28(2):103-15. PubMed ID: 9522436
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB; Surry D; Price RJ; Lake BG; Evans DC
    Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Relative quantities of catalytically active CYP 2C9 and 2C19 in human liver microsomes: application of the relative activity factor approach.
    Venkatakrishnan K; von Moltke LL; Greenblatt DJ
    J Pharm Sci; 1998 Jul; 87(7):845-53. PubMed ID: 9649353
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes.
    Transon C; Lecoeur S; Leemann T; Beaune P; Dayer P
    Eur J Clin Pharmacol; 1996; 51(1):79-85. PubMed ID: 8880056
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase.
    Crespi CL; Miller VP
    Pharmacogenetics; 1997 Jun; 7(3):203-10. PubMed ID: 9241660
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6.
    Voorman RL; Payne NA; Wienkers LC; Hauer MJ; Sanders PE
    Drug Metab Dispos; 2001 Jan; 29(1):41-7. PubMed ID: 11124228
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro.
    Ufer M; Svensson JO; Krausz KW; Gelboin HV; Rane A; Tybring G
    Eur J Clin Pharmacol; 2004 May; 60(3):173-82. PubMed ID: 15054565
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9.
    Wen X; Wang JS; Backman JT; Kivistö KT; Neuvonen PJ
    Drug Metab Dispos; 2001 Nov; 29(11):1359-61. PubMed ID: 11602509
    [TBL] [Abstract][Full Text] [Related]  

  • 33. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X; Wang JS; Kivistö KT; Neuvonen PJ; Backman JT
    Br J Clin Pharmacol; 2001 Nov; 52(5):547-53. PubMed ID: 11736863
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Metabolism of Meloxicam in human liver involves cytochromes P4502C9 and 3A4.
    Chesné C; Guyomard C; Guillouzo A; Schmid J; Ludwig E; Sauter T
    Xenobiotica; 1998 Jan; 28(1):1-13. PubMed ID: 9493314
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.
    Chang SY; Li W; Traeger SC; Wang B; Cui D; Zhang H; Wen B; Rodrigues AD
    Drug Metab Dispos; 2008 Dec; 36(12):2513-22. PubMed ID: 18787056
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Evidence for involvement of polymorphic CYP2C19 and 2C9 in the N-demethylation of sertraline in human liver microsomes.
    Xu ZH; Wang W; Zhao XJ; Huang SL; Zhu B; He N; Shu Y; Liu ZQ; Zhou HH
    Br J Clin Pharmacol; 1999 Sep; 48(3):416-23. PubMed ID: 10510155
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples.
    Yamazaki H; Inoue K; Shaw PM; Checovich WJ; Guengerich FP; Shimada T
    J Pharmacol Exp Ther; 1997 Nov; 283(2):434-42. PubMed ID: 9353355
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Roles of cytochromes P450 1A2, 2A6, and 2C8 in 5-fluorouracil formation from tegafur, an anticancer prodrug, in human liver microsomes.
    Komatsu T; Yamazaki H; Shimada N; Nakajima M; Yokoi T
    Drug Metab Dispos; 2000 Dec; 28(12):1457-63. PubMed ID: 11095583
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone.
    Korhonen T; Turpeinen M; Tolonen A; Laine K; Pelkonen O
    J Steroid Biochem Mol Biol; 2008 May; 110(1-2):56-66. PubMed ID: 18356043
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K; von Moltke LL; Duan SX; Fleishaker JC; Shader RI; Greenblatt DJ
    J Pharm Pharmacol; 1998 Mar; 50(3):265-74. PubMed ID: 9600717
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 63.