BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 10775267)

  • 1. Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia.
    Liu Q; Schwaller J; Kutok J; Cain D; Aster JC; Williams IR; Gilliland DG
    EMBO J; 2000 Apr; 19(8):1827-38. PubMed ID: 10775267
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells.
    Wai DH; Knezevich SR; Lucas T; Jansen B; Kay RJ; Sorensen PH
    Oncogene; 2000 Feb; 19(7):906-15. PubMed ID: 10702799
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways.
    Guasch G; Ollendorff V; Borg JP; Birnbaum D; Pébusque MJ
    Mol Cell Biol; 2001 Dec; 21(23):8129-42. PubMed ID: 11689702
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The detection of Tel-TrkC chimeric transcripts is more specific than TrkC immunoreactivity for the diagnosis of congenital fibrosarcoma.
    Dubus P; Coindre JM; Groppi A; Jouan H; Ferrer J; Cohen C; Rivel J; Copin MC; Leroy JP; de Muret A; Merlio JP
    J Pathol; 2001 Jan; 193(1):88-94. PubMed ID: 11169520
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma.
    Knezevich SR; McFadden DE; Tao W; Lim JF; Sorensen PH
    Nat Genet; 1998 Feb; 18(2):184-7. PubMed ID: 9462753
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways.
    Sternberg DW; Tomasson MH; Carroll M; Curley DP; Barker G; Caprio M; Wilbanks A; Kazlauskas A; Gilliland DG
    Blood; 2001 Dec; 98(12):3390-7. PubMed ID: 11719379
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581.
    Tomasson MH; Sternberg DW; Williams IR; Carroll M; Cain D; Aster JC; Ilaria RL; Van Etten RA; Gilliland DG
    J Clin Invest; 2000 Feb; 105(4):423-32. PubMed ID: 10683371
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Constitutive activation of STAT3 and STAT5 is induced by leukemic fusion proteins with protein tyrosine kinase activity and is sufficient for transformation of hematopoietic precursor cells.
    Spiekermann K; Pau M; Schwab R; Schmieja K; Franzrahe S; Hiddemann W
    Exp Hematol; 2002 Mar; 30(3):262-71. PubMed ID: 11882364
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TEL-Syk fusion constitutively activates PI3-K/Akt, MAPK and JAK2-independent STAT5 signal pathways.
    Kanie T; Abe A; Matsuda T; Kuno Y; Towatari M; Yamamoto T; Saito H; Emi N; Naoe T
    Leukemia; 2004 Mar; 18(3):548-55. PubMed ID: 14749700
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia.
    Lacronique V; Boureux A; Valle VD; Poirel H; Quang CT; Mauchauffé M; Berthou C; Lessard M; Berger R; Ghysdael J; Bernard OA
    Science; 1997 Nov; 278(5341):1309-12. PubMed ID: 9360930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma.
    Rubin BP; Chen CJ; Morgan TW; Xiao S; Grier HE; Kozakewich HP; Perez-Atayde AR; Fletcher JA
    Am J Pathol; 1998 Nov; 153(5):1451-8. PubMed ID: 9811336
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells.
    Lacronique V; Boureux A; Monni R; Dumon S; Mauchauffé M; Mayeux P; Gouilleux F; Berger R; Gisselbrecht S; Ghysdael J; Bernard OA
    Blood; 2000 Mar; 95(6):2076-83. PubMed ID: 10706877
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tel/PDGFRbeta induces stem cell differentiation via the Ras/ERK and STAT5 signaling pathways.
    Dobbin E; Graham C; Corrigan PM; Thomas KG; Freeburn RW; Wheadon H
    Exp Hematol; 2009 Jan; 37(1):111-121. PubMed ID: 19100521
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway.
    Santos SC; Lacronique V; Bouchaert I; Monni R; Bernard O; Gisselbrecht S; Gouilleux F
    Oncogene; 2001 Apr; 20(17):2080-90. PubMed ID: 11360192
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes.
    Schwaller J; Frantsve J; Aster J; Williams IR; Tomasson MH; Ross TS; Peeters P; Van Rompaey L; Van Etten RA; Ilaria R; Marynen P; Gilliland DG
    EMBO J; 1998 Sep; 17(18):5321-33. PubMed ID: 9736611
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: a common mechanism for transformation by tyrosine kinase fusion proteins.
    Wilbanks AM; Mahajan S; Frank DA; Druker BJ; Gilliland DG; Carroll M
    Exp Hematol; 2000 May; 28(5):584-93. PubMed ID: 10812249
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fusion of ETV6 to neurotrophin-3 receptor TRKC in acute myeloid leukemia with t(12;15)(p13;q25).
    Eguchi M; Eguchi-Ishimae M; Tojo A; Morishita K; Suzuki K; Sato Y; Kudoh S; Tanaka K; Setoyama M; Nagamura F; Asano S; Kamada N
    Blood; 1999 Feb; 93(4):1355-63. PubMed ID: 9949179
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a SRC-like tyrosine kinase gene, FRK, fused with ETV6 in a patient with acute myelogenous leukemia carrying a t(6;12)(q21;p13) translocation.
    Hosoya N; Qiao Y; Hangaishi A; Wang L; Nannya Y; Sanada M; Kurokawa M; Chiba S; Hirai H; Ogawa S
    Genes Chromosomes Cancer; 2005 Mar; 42(3):269-79. PubMed ID: 15611931
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Congenital-infantile fibrosarcoma. A clinicopathologic study of 10 cases and molecular detection of the ETV6-NTRK3 fusion transcripts using paraffin-embedded tissues.
    Sheng WQ; Hisaoka M; Okamoto S; Tanaka A; Meis-Kindblom JM; Kindblom LG; Ishida T; Nojima T; Hashimoto H
    Am J Clin Pathol; 2001 Mar; 115(3):348-55. PubMed ID: 11242790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation.
    Frantsve J; Schwaller J; Sternberg DW; Kutok J; Gilliland DG
    Mol Cell Biol; 2001 May; 21(10):3547-57. PubMed ID: 11313480
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.