375 related articles for article (PubMed ID: 10777494)
21. Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state.
Rehmann H; Das J; Knipscheer P; Wittinghofer A; Bos JL
Nature; 2006 Feb; 439(7076):625-8. PubMed ID: 16452984
[TBL] [Abstract][Full Text] [Related]
22. cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membrane.
Consonni SV; Gloerich M; Spanjaard E; Bos JL
Proc Natl Acad Sci U S A; 2012 Mar; 109(10):3814-9. PubMed ID: 22343288
[TBL] [Abstract][Full Text] [Related]
23. Origin and Isoform Specific Functions of Exchange Proteins Directly Activated by cAMP: A Phylogenetic Analysis.
Ni Z; Cheng X
Cells; 2021 Oct; 10(10):. PubMed ID: 34685730
[TBL] [Abstract][Full Text] [Related]
24. Exchange protein directly activated by cAMP 1 (Epac1) is expressed in human neutrophils and mediates cAMP-dependent activation of the monomeric GTPase Rap1.
Dash-Koney M; Deevi RK; McFarlane C; Dib K
J Leukoc Biol; 2011 Oct; 90(4):741-9. PubMed ID: 21750123
[TBL] [Abstract][Full Text] [Related]
25. Possible roles of the cAMP-mediators EPAC and RAP1 in decidualization of rat uterus.
Kusama K; Yoshie M; Tamura K; Daikoku T; Takarada T; Tachikawa E
Reproduction; 2014 Jun; 147(6):897-906. PubMed ID: 24586073
[TBL] [Abstract][Full Text] [Related]
26. Microtubule-associated protein 1B-light chain 1 enhances activation of Rap1 by exchange protein activated by cyclic AMP but not intracellular targeting.
Borland G; Gupta M; Magiera MM; Rundell CJ; Fuld S; Yarwood SJ
Mol Pharmacol; 2006 Jan; 69(1):374-84. PubMed ID: 16244178
[TBL] [Abstract][Full Text] [Related]
27. Entropy-driven cAMP-dependent allosteric control of inhibitory interactions in exchange proteins directly activated by cAMP.
Das R; Mazhab-Jafari MT; Chowdhury S; SilDas S; Selvaratnam R; Melacini G
J Biol Chem; 2008 Jul; 283(28):19691-703. PubMed ID: 18411261
[TBL] [Abstract][Full Text] [Related]
28. Rap1 activation plays a regulatory role in pancreatic amylase secretion.
Sabbatini ME; Chen X; Ernst SA; Williams JA
J Biol Chem; 2008 Aug; 283(35):23884-94. PubMed ID: 18577515
[TBL] [Abstract][Full Text] [Related]
29. Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac.
Dupuy AG; L'Hoste S; Cherfils J; Camonis J; Gaudriault G; de Gunzburg J
Oncogene; 2005 Jun; 24(28):4509-20. PubMed ID: 15856025
[TBL] [Abstract][Full Text] [Related]
30. cAMP-Epac2-mediated activation of Rap1 in developing male germ cells: RA-RhoGAP as a possible direct down-stream effector.
Aivatiadou E; Ripolone M; Brunetti F; Berruti G
Mol Reprod Dev; 2009 Apr; 76(4):407-16. PubMed ID: 18937323
[TBL] [Abstract][Full Text] [Related]
31. Isoform-specific antagonists of exchange proteins directly activated by cAMP.
Tsalkova T; Mei FC; Li S; Chepurny OG; Leech CA; Liu T; Holz GG; Woods VL; Cheng X
Proc Natl Acad Sci U S A; 2012 Nov; 109(45):18613-8. PubMed ID: 23091014
[TBL] [Abstract][Full Text] [Related]
32. Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1.
Baameur F; Singhmar P; Zhou Y; Hancock JF; Cheng X; Heijnen CJ; Kavelaars A
Sci Rep; 2016 Nov; 6():36370. PubMed ID: 27808165
[TBL] [Abstract][Full Text] [Related]
33. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.
Rangarajan S; Enserink JM; Kuiperij HB; de Rooij J; Price LS; Schwede F; Bos JL
J Cell Biol; 2003 Feb; 160(4):487-93. PubMed ID: 12578910
[TBL] [Abstract][Full Text] [Related]
34. Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis.
Tiwari S; Felekkis K; Moon EY; Flies A; Sherr DH; Lerner A
Blood; 2004 Apr; 103(7):2661-7. PubMed ID: 14615375
[TBL] [Abstract][Full Text] [Related]
35. Small GTPase Rap1 regulates cell migration through regulation of small GTPase RhoA activity in response to transforming growth factor-β1.
Moon MY; Kim HJ; Kim JG; Lee JY; Kim J; Kim SC; Choi IG; Kim PH; Park JB
J Cell Physiol; 2013 Nov; 228(11):2119-26. PubMed ID: 23559363
[TBL] [Abstract][Full Text] [Related]
36. Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1.
Beck EM; Parnell E; Cowley A; Porter A; Gillespie J; Robinson J; Robinson L; Pannifer AD; Hamon V; Jones P; Morrison A; McElroy S; Timmerman M; Rutjes H; Mahajan P; Wiejak J; Luchowska-Stańska U; Morgan D; Barker G; Rehmann H; Yarwood SJ
Cells; 2019 Nov; 8(11):. PubMed ID: 31726720
[TBL] [Abstract][Full Text] [Related]
37. RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activation.
Liao Y; Satoh T; Gao X; Jin TG; Hu CD; Kataoka T
J Biol Chem; 2001 Jul; 276(30):28478-83. PubMed ID: 11359771
[TBL] [Abstract][Full Text] [Related]
38. Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy.
Ulucan C; Wang X; Baljinnyam E; Bai Y; Okumura S; Sato M; Minamisawa S; Hirotani S; Ishikawa Y
Am J Physiol Heart Circ Physiol; 2007 Sep; 293(3):H1662-72. PubMed ID: 17557924
[TBL] [Abstract][Full Text] [Related]
39. Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells.
Aumo L; Rusten M; Mellgren G; Bakke M; Lewis AE
Endocrinology; 2010 May; 151(5):2151-61. PubMed ID: 20233795
[TBL] [Abstract][Full Text] [Related]
40. Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2.
Liu C; Takahashi M; Li Y; Song S; Dillon TJ; Shinde U; Stork PJ
Mol Cell Biol; 2008 Dec; 28(23):7109-25. PubMed ID: 18824540
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
