BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 10777585)

  • 1. Roles of thermal instability and proteolytic cleavage in regulation of activated thrombin-activable fibrinolysis inhibitor.
    Boffa MB; Bell R; Stevens WK; Nesheim ME
    J Biol Chem; 2000 Apr; 275(17):12868-78. PubMed ID: 10777585
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of active thrombin-activable fibrinolysis inhibitor takes place by a process that involves conformational instability rather than proteolytic cleavage.
    Marx PF; Hackeng TM; Dawson PE; Griffin JH; Meijers JC; Bouma BN
    J Biol Chem; 2000 Apr; 275(17):12410-5. PubMed ID: 10777524
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Plasma and recombinant thrombin-activable fibrinolysis inhibitor (TAFI) and activated TAFI compared with respect to glycosylation, thrombin/thrombomodulin-dependent activation, thermal stability, and enzymatic properties.
    Boffa MB; Wang W; Bajzar L; Nesheim ME
    J Biol Chem; 1998 Jan; 273(4):2127-35. PubMed ID: 9442053
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The intrinsic threshold of the fibrinolytic system is modulated by basic carboxypeptidases, but the magnitude of the antifibrinolytic effect of activated thrombin-activable fibrinolysis inhibitor is masked by its instability.
    Walker JB; Bajzar L
    J Biol Chem; 2004 Jul; 279(27):27896-904. PubMed ID: 15128744
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Generation of a stable activated thrombin activable fibrinolysis inhibitor variant.
    Ceresa E; Van de Borne K; Peeters M; Lijnen HR; Declerck PJ; Gils A
    J Biol Chem; 2006 Jun; 281(23):15878-83. PubMed ID: 16595693
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative evaluation of stable TAFIa variants: importance of alpha-helix 9 and beta-sheet 11 for TAFIa (in)stability.
    Ceresa E; De Maeyer M; Jonckheer A; Peeters M; Engelborghs Y; Declerck PJ; Gils A
    J Thromb Haemost; 2007 Oct; 5(10):2105-12. PubMed ID: 17666015
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of isoleucine residues 182 and 183 in thrombin-activatable fibrinolysis inhibitor.
    Marx PF; Havik SR; Bouma BN; Meijers JC
    J Thromb Haemost; 2005 Jun; 3(6):1293-300. PubMed ID: 15946220
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Two naturally occurring variants of TAFI (Thr-325 and Ile-325) differ substantially with respect to thermal stability and antifibrinolytic activity of the enzyme.
    Schneider M; Boffa M; Stewart R; Rahman M; Koschinsky M; Nesheim M
    J Biol Chem; 2002 Jan; 277(2):1021-30. PubMed ID: 11684677
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thrombin-activable fibrinolysis inhibitor zymogen does not play a significant role in the attenuation of fibrinolysis.
    Foley JH; Kim P; Nesheim ME
    J Biol Chem; 2008 Apr; 283(14):8863-7. PubMed ID: 18252711
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of zinc ions in activation and inactivation of thrombin-activatable fibrinolysis inhibitor.
    Marx PF; Bouma BN; Meijers JC
    Biochemistry; 2002 Jan; 41(4):1211-6. PubMed ID: 11802720
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Monoclonal antibodies targeting the antifibrinolytic activity of activated thrombin-activatable fibrinolysis inhibitor but not the anti-inflammatory activity on osteopontin and C5a.
    Semeraro F; Ammollo CT; Gils A; Declerck PJ; Colucci M
    J Thromb Haemost; 2013 Dec; 11(12):2137-47. PubMed ID: 24134522
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into thrombin activatable fibrinolysis inhibitor function and regulation.
    Foley JH; Kim PY; Mutch NJ; Gils A
    J Thromb Haemost; 2013 Jun; 11 Suppl 1():306-15. PubMed ID: 23809134
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Plasmin-mediated activation and inactivation of thrombin-activatable fibrinolysis inhibitor.
    Marx PF; Dawson PE; Bouma BN; Meijers JC
    Biochemistry; 2002 May; 41(21):6688-96. PubMed ID: 12022872
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity.
    Zhou X; Weeks SD; Ameloot P; Callewaert N; Strelkov SV; Declerck PJ
    J Thromb Haemost; 2016 Aug; 14(8):1629-38. PubMed ID: 27279497
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thrombin activatable fibrinolysis inhibitor, a potential regulator of vascular inflammation.
    Myles T; Nishimura T; Yun TH; Nagashima M; Morser J; Patterson AJ; Pearl RG; Leung LL
    J Biol Chem; 2003 Dec; 278(51):51059-67. PubMed ID: 14525995
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Generation and characterization of a highly stable form of activated thrombin-activable fibrinolysis inhibitor.
    Marx PF; Havik SR; Marquart JA; Bouma BN; Meijers JC
    J Biol Chem; 2004 Feb; 279(8):6620-8. PubMed ID: 14660622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Generation of a stable thrombin-activatable fibrinolysis inhibitor deletion mutant exerting full carboxypeptidase activity without activation.
    Zhou X; Declerck PJ
    J Thromb Haemost; 2015 Jun; 13(6):1084-9. PubMed ID: 25773535
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Both cellular and soluble forms of thrombomodulin inhibit fibrinolysis by potentiating the activation of thrombin-activable fibrinolysis inhibitor.
    Bajzar L; Nesheim M; Morser J; Tracy PB
    J Biol Chem; 1998 Jan; 273(5):2792-8. PubMed ID: 9446587
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a thrombomodulin interaction site on thrombin-activatable fibrinolysis inhibitor that mediates accelerated activation by thrombin.
    Marar TT; Boffa MB
    J Thromb Haemost; 2016 Apr; 14(4):772-83. PubMed ID: 26816270
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation.
    Marx PF; Brondijk TH; Plug T; Romijn RA; Hemrika W; Meijers JC; Huizinga EG
    Blood; 2008 Oct; 112(7):2803-9. PubMed ID: 18559974
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.