BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 10779626)

  • 1. Development of a novel (32)P-postlabeling method for the analysis of 3'-azido-3'-deoxythymidine.
    Fang JL; Beland FA
    Cancer Lett; 2000 May; 153(1-2):25-33. PubMed ID: 10779626
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Plasma drug levels compared with DNA incorporation of 3'-azido-3'-deoxythymidine (AZT) in adult cynomolgus (Macaca fascicularis) monkeys.
    Olivero OA; Reddy MK; Pietras SM; Poirier MC
    Exp Biol Med (Maywood); 2001 May; 226(5):446-9. PubMed ID: 11393173
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantitative analysis of 3'-azido-3'-deoxythymidine incorporation into DNA in human colon tumor cells.
    Sharma M; Jain R; Ionescu E; Darnowski JW
    Bioconjug Chem; 1995; 6(5):536-40. PubMed ID: 8974451
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.
    Boyer PL; Sarafianos SG; Arnold E; Hughes SH
    J Virol; 2001 May; 75(10):4832-42. PubMed ID: 11312355
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in mice treated neonatally with zidovudine and didanosine.
    Von Tungeln LS; Dobrovolsky VN; Bishop ME; Shaddock JG; Heflich RH; Beland FA
    Mutagenesis; 2004 Jul; 19(4):307-11. PubMed ID: 15215330
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transplacental drug transfer and frequency of Tk and Hprt lymphocyte mutants and peripheral blood micronuclei in mice treated transplacentally with zidovudine and lamivudine.
    Von Tungeln LS; Williams LD; Doerge DR; Shaddock JG; McGarrity LJ; Morris SM; Mittelstaedt RA; Heflich RH; Beland FA
    Environ Mol Mutagen; 2007; 48(3-4):258-69. PubMed ID: 16850453
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Incorporation of 3'-azido-3'-deoxythymidine (AZT) into fetal DNA and fetal tissue distribution of drug after infusion of pregnant late-term rhesus macaques with a human-equivalent AZT dose.
    Poirier MC; Patterson TA; Slikker W; Olivero OA
    J Acquir Immune Defic Syndr; 1999 Dec; 22(5):477-83. PubMed ID: 10961609
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 3'-azido-3'-deoxythymidine induces deletions in L5178Y mouse lymphoma cells.
    Wang J; Chen T; Honma M; Chen L; Moore MM
    Environ Mol Mutagen; 2007; 48(3-4):248-57. PubMed ID: 17358034
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine.
    Meng Q; Su T; Olivero OA; Poirier MC; Shi X; Ding X; Walker VE
    Toxicol Sci; 2000 Apr; 54(2):322-9. PubMed ID: 10774814
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyrimidine deoxynucleoside and nucleoside reverse transcriptase inhibitor metabolism in the perfused heart and isolated mitochondria.
    Morris GW; Laclair DD; McKee EE
    Antivir Ther; 2010; 15(4):587-97. PubMed ID: 20587852
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3'-Azido-3'-deoxythymidine cytotoxicity and metabolism in the human colon tumor cell line HCT-8.
    Darnowski JW; Goulette FA
    Biochem Pharmacol; 1994 Nov; 48(9):1797-805. PubMed ID: 7980649
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
    Periclou AP; Nandy P; Avramis VI
    In Vivo; 2000; 14(3):377-88. PubMed ID: 10904870
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intracellular metabolism of 3'-azido-3'-deoxythymidine (AZT): a nuclear magnetic resonance study on T-lymphoblastoid cell lines with different resistance to AZT.
    Di Vito M; Bozzi A; Ferretti A; Cianfriglia M; Barca S; Signoretti C; Lenti L; d'Agostino F; Strom R; Podo F
    Biochem Pharmacol; 1997 Nov; 54(9):979-90. PubMed ID: 9374418
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line.
    Prakash O; Tang ZY; Zhou P; Peng X; Kolls J; Shellito JE; Nelson S
    Alcohol Clin Exp Res; 2002 Mar; 26(3):295-302. PubMed ID: 11923581
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
    Boyer PL; Sarafianos SG; Arnold E; Hughes SH
    J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitors.
    Olivero OA
    Environ Mol Mutagen; 2007; 48(3-4):215-23. PubMed ID: 16395695
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure and conformational analysis of the anti-HIV reverse transcriptase inhibitor AZT using MP2 and DFT methods. Differences with the natural nucleoside thymidine. Simulation of the 1st phosphorylation step with ATP.
    Palafox MA
    Phys Chem Chem Phys; 2014 Dec; 16(45):24763-83. PubMed ID: 25317835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
    Kerr SG; Anderson KS
    Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of Zidovudine Treatment on Heart mRNA Expression and Mitochondrial DNA Copy Number Associated with Alterations in Deoxynucleoside Triphosphate Composition in a Neonatal Rat Model.
    Snowdin JW; Hsiung CH; Kesterson DG; Kamath VG; McKee EE
    Antimicrob Agents Chemother; 2015 Oct; 59(10):6328-36. PubMed ID: 26248377
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of thymidine and uridine on the phosphorylation of 3'-azido-3'-deoxythymidine (zidovudine) in human mononuclear cells.
    Szebeni J; Patel SS; Hung K; Wahl LM; Weinstein JN
    Antimicrob Agents Chemother; 1991 Jan; 35(1):198-200. PubMed ID: 2014977
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.