181 related articles for article (PubMed ID: 10780528)
1. Enhancement of the anti-tumour effect of cyclophosphamide by the bioreductive drugs AQ4N and tirapazamine.
Friery OP; Gallagher R; Murray MM; Hughes CM; Galligan ES; McIntyre IA; Patterson LH; Hirst DG; McKeown SR
Br J Cancer; 2000 Apr; 82(8):1469-73. PubMed ID: 10780528
[TBL] [Abstract][Full Text] [Related]
2. The chemopotentiation of cisplatin by the novel bioreductive drug AQ4N.
Gallagher R; Hughes CM; Murray MM; Friery OP; Patterson LH; Hirst DG; McKeown SR
Br J Cancer; 2001 Aug; 85(4):625-9. PubMed ID: 11506506
[TBL] [Abstract][Full Text] [Related]
3. Enhancement of chemotherapy and radiotherapy of murine tumours by AQ4N, a bioreductively activated anti-tumour agent.
Patterson LH; McKeown SR; Ruparelia K; Double JA; Bibby MC; Cole S; Stratford IJ
Br J Cancer; 2000 Jun; 82(12):1984-90. PubMed ID: 10864207
[TBL] [Abstract][Full Text] [Related]
4. Evidence for a therapeutic gain when AQ4N or tirapazamine is combined with radiation.
McKeown SR; Friery OP; McIntyre IA; Hejmadi MV; Patterson LH; Hirst DG
Br J Cancer Suppl; 1996 Jul; 27():S39-42. PubMed ID: 8763843
[TBL] [Abstract][Full Text] [Related]
5. AQ4N: an alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo.
McKeown SR; Hejmadi MV; McIntyre IA; McAleer JJ; Patterson LH
Br J Cancer; 1995 Jul; 72(1):76-81. PubMed ID: 7599069
[TBL] [Abstract][Full Text] [Related]
6. The in situ tumour response to combinations of cyclophosphamide and tirapazamine.
Siemann DW
Br J Cancer Suppl; 1996 Jul; 27():S65-9. PubMed ID: 8763849
[TBL] [Abstract][Full Text] [Related]
7. Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs.
Lash CJ; Li AE; Rutland M; Baguley BC; Zwi LJ; Wilson WR
Br J Cancer; 1998 Aug; 78(4):439-45. PubMed ID: 9716024
[TBL] [Abstract][Full Text] [Related]
8. A cytochrome P450 2B6 meditated gene therapy strategy to enhance the effects of radiation or cyclophosphamide when combined with the bioreductive drug AQ4N.
McErlane V; Yakkundi A; McCarthy HO; Hughes CM; Patterson LH; Hirst DG; Robson T; McKeown SR
J Gene Med; 2005 Jul; 7(7):851-9. PubMed ID: 15712360
[TBL] [Abstract][Full Text] [Related]
9. DNA damage following combination of radiation with the bioreductive drug AQ4N: possible selective toxicity to oxic and hypoxic tumour cells.
Hejmadi MV; McKeown SR; Friery OP; McIntyre IA; Patterson LH; Hirst DG
Br J Cancer; 1996 Feb; 73(4):499-505. PubMed ID: 8595165
[TBL] [Abstract][Full Text] [Related]
10. Synergistic enhancement of the antitumor effect of taxol by the bioreductive compound NLCQ-1, in vivo: comparison with tirapazamine.
Papadopoulou MV; Ji M; Bloomer WD
Oncol Res; 2002; 13(1):47-54. PubMed ID: 12201674
[TBL] [Abstract][Full Text] [Related]
11. Potentiation of cisplatin activity by the bioreductive agent tirapazamine.
Siemann DW; Hinchman CA
Radiother Oncol; 1998 May; 47(2):215-20. PubMed ID: 9683372
[TBL] [Abstract][Full Text] [Related]
12. AQ4N: a new approach to hypoxia-activated cancer chemotherapy.
Patterson LH; McKeown SR
Br J Cancer; 2000 Dec; 83(12):1589-93. PubMed ID: 11104551
[TBL] [Abstract][Full Text] [Related]
13. DNA damage induced in T50/80 tumour cells following exposure to the bioreductive drug Tirapazamine in combination with a single dose of radiation (12Gy).
Friery OP; Hejmadi MV; McKeown SR
Biochem Soc Trans; 1997 Feb; 25(1):135S. PubMed ID: 9057033
[No Abstract] [Full Text] [Related]
14. Schedule-dependent potentiation of chemotherapeutic drugs by the bioreductive compounds NLCQ-1 and tirapazamine against EMT6 tumors in mice.
Papadopoulou MV; Ji M; Bloomer WD
Cancer Chemother Pharmacol; 2001 Aug; 48(2):160-8. PubMed ID: 11561782
[TBL] [Abstract][Full Text] [Related]
15. Bioreductive GDEPT using cytochrome P450 3A4 in combination with AQ4N.
McCarthy HO; Yakkundi A; McErlane V; Hughes CM; Keilty G; Murray M; Patterson LH; Hirst DG; McKeown SR; Robson T
Cancer Gene Ther; 2003 Jan; 10(1):40-8. PubMed ID: 12489027
[TBL] [Abstract][Full Text] [Related]
16. Combination of the bioreductive drug tirapazamine with the chemotherapeutic prodrug cyclophosphamide for P450/P450-reductase-based cancer gene therapy.
Jounaidi Y; Waxman DJ
Cancer Res; 2000 Jul; 60(14):3761-9. PubMed ID: 10919648
[TBL] [Abstract][Full Text] [Related]
17. The effect of tirapazamine (SR-4233) alone or combined with chemotherapeutic agents on xenografted human tumours.
Lartigau E; Guichard M
Br J Cancer; 1996 Jun; 73(12):1480-5. PubMed ID: 8664116
[TBL] [Abstract][Full Text] [Related]
18. Hypoxia-dependent retinal toxicity of NLCQ-1 (NSC 709257) in BALB/c mice. Comparison with tirapazamine.
Papadopoulou MV; Ji M; Bloomer WD
Basic Clin Pharmacol Toxicol; 2011 Jun; 108(6):396-9. PubMed ID: 21205223
[TBL] [Abstract][Full Text] [Related]
19. Bioreductive drugs: from concept to clinic.
McKeown SR; Cowen RL; Williams KJ
Clin Oncol (R Coll Radiol); 2007 Aug; 19(6):427-42. PubMed ID: 17482438
[TBL] [Abstract][Full Text] [Related]
20. Antitumour prodrug development using cytochrome P450 (CYP) mediated activation.
Patterson LH; McKeown SR; Robson T; Gallagher R; Raleigh SM; Orr S
Anticancer Drug Des; 1999 Dec; 14(6):473-86. PubMed ID: 10834269
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
