BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 10787428)

  • 1. Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments.
    Garver WS; Heidenreich RA; Erickson RP; Thomas MA; Wilson JM
    J Lipid Res; 2000 May; 41(5):673-87. PubMed ID: 10787428
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease.
    Patel SC; Suresh S; Kumar U; Hu CY; Cooney A; Blanchette-Mackie EJ; Neufeld EB; Patel RC; Brady RO; Patel YC; Pentchev PG; Ong WY
    Proc Natl Acad Sci U S A; 1999 Feb; 96(4):1657-62. PubMed ID: 9990080
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo.
    Neufeld EB; Wastney M; Patel S; Suresh S; Cooney AM; Dwyer NK; Roff CF; Ohno K; Morris JA; Carstea ED; Incardona JP; Strauss JF; Vanier MT; Patterson MC; Brady RO; Pentchev PG; Blanchette-Mackie EJ
    J Biol Chem; 1999 Apr; 274(14):9627-35. PubMed ID: 10092649
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Niemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization.
    Watari H; Blanchette-Mackie EJ; Dwyer NK; Glick JM; Patel S; Neufeld EB; Brady RO; Pentchev PG; Strauss JF
    Proc Natl Acad Sci U S A; 1999 Feb; 96(3):805-10. PubMed ID: 9927649
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol.
    Cruz JC; Sugii S; Yu C; Chang TY
    J Biol Chem; 2000 Feb; 275(6):4013-21. PubMed ID: 10660558
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols.
    Frolov A; Zielinski SE; Crowley JR; Dudley-Rucker N; Schaffer JE; Ory DS
    J Biol Chem; 2003 Jul; 278(28):25517-25. PubMed ID: 12719428
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemann-Pick type C1 mice.
    Reid PC; Sugii S; Chang TY
    J Lipid Res; 2003 May; 44(5):1010-9. PubMed ID: 12611909
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations in the leucine zipper motif and sterol-sensing domain inactivate the Niemann-Pick C1 glycoprotein.
    Watari H; Blanchette-Mackie EJ; Dwyer NK; Watari M; Neufeld EB; Patel S; Pentchev PG; Strauss JF
    J Biol Chem; 1999 Jul; 274(31):21861-6. PubMed ID: 10419504
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function.
    Frolov A; Srivastava K; Daphna-Iken D; Traub LM; Schaffer JE; Ory DS
    J Biol Chem; 2001 Dec; 276(49):46414-21. PubMed ID: 11571306
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1.
    Sun X; Marks DL; Park WD; Wheatley CL; Puri V; O'Brien JF; Kraft DL; Lundquist PA; Patterson MC; Pagano RE; Snow K
    Am J Hum Genet; 2001 Jun; 68(6):1361-72. PubMed ID: 11349231
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain.
    Liao G; Yao Y; Liu J; Yu Z; Cheung S; Xie A; Liang X; Bi X
    Am J Pathol; 2007 Sep; 171(3):962-75. PubMed ID: 17631520
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transmembrane molecular pump activity of Niemann-Pick C1 protein.
    Davies JP; Chen FW; Ioannou YA
    Science; 2000 Dec; 290(5500):2295-8. PubMed ID: 11125140
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of liver disease and lipid metabolism in the Niemann-Pick C1 mouse.
    Garver WS; Jelinek D; Oyarzo JN; Flynn J; Zuckerman M; Krishnan K; Chung BH; Heidenreich RA
    J Cell Biochem; 2007 May; 101(2):498-516. PubMed ID: 17216601
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes.
    Zhang M; Dwyer NK; Neufeld EB; Love DC; Cooney A; Comly M; Patel S; Watari H; Strauss JF; Pentchev PG; Hanover JA; Blanchette-Mackie EJ
    J Biol Chem; 2001 Feb; 276(5):3417-25. PubMed ID: 11032830
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Relevance of Niemann-Pick type C1 protein expression in controlling plasma cholesterol and biliary lipid secretion in mice.
    Amigo L; Mendoza H; Castro J; QuiƱones V; Miquel JF; Zanlungo S
    Hepatology; 2002 Oct; 36(4 Pt 1):819-28. PubMed ID: 12297829
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correction of apolipoprotein A-I-mediated lipid efflux and high density lipoprotein particle formation in human Niemann-Pick type C disease fibroblasts.
    Boadu E; Choi HY; Lee DW; Waddington EI; Chan T; Asztalos B; Vance JE; Chan A; Castro G; Francis GA
    J Biol Chem; 2006 Dec; 281(48):37081-90. PubMed ID: 17020879
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Niemann-Pick C1 protein in feline fibroblasts.
    Garver WS; Somers K; Krishnan K; Mitchell T; Heidenreich RA; Thrall MA
    Mol Genet Metab; 2002 May; 76(1):31-6. PubMed ID: 12175778
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol.
    Sokol J; Blanchette-Mackie J; Kruth HS; Dwyer NK; Amende LM; Butler JD; Robinson E; Patel S; Brady RO; Comly ME
    J Biol Chem; 1988 Mar; 263(7):3411-7. PubMed ID: 3277970
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann-Pick C1-deficient neurons.
    Karten B; Vance DE; Campenot RB; Vance JE
    J Neurochem; 2002 Dec; 83(5):1154-63. PubMed ID: 12437586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
    Boadu E; Nelson RC; Francis GA
    Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.