BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 10794706)

  • 1. Subtype-selective N-methyl-D-aspartate receptor antagonists: benzimidazalone and hydantoin as phenol replacements.
    Schelkun RM; Yuen PW; Serpa K; Meltzer LT; Wise LD; Whittemore ER; Woodward RM
    J Med Chem; 2000 May; 43(9):1892-7. PubMed ID: 10794706
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(heteroarylalkynyl)-4-benzylpiperidines.
    Wright JL; Gregory TF; Kesten SR; Boxer PA; Serpa KA; Meltzer LT; Wise LD; Espitia SA; Konkoy CS; Whittemore ER; Woodward RM
    J Med Chem; 2000 Sep; 43(18):3408-19. PubMed ID: 10978188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(arylalkynyl)-4-benzylpiperidines.
    Wright JL; Gregory TF; Bigge CF; Boxer PA; Serpa K; Meltzer LT; Wise LD; Cai SX; Hawkinson JE; Konkoy CS; Whittemore ER; Woodward RM; Zhou ZL
    J Med Chem; 1999 Jul; 42(13):2469-77. PubMed ID: 10395488
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: a novel, potent, and selective NR1/2B NMDA receptor antagonist.
    Zhou ZL; Cai SX; Whittemore ER; Konkoy CS; Espitia SA; Tran M; Rock DM; Coughenour LL; Hawkinson JE; Boxer PA; Bigge CF; Wise LD; Weber E; Woodward RM; Keana JF
    J Med Chem; 1999 Jul; 42(15):2993-3000. PubMed ID: 10425109
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of N-substituted 4-(4-hydroxyphenyl)piperidines, 4-(4-hydroxybenzyl)piperidines, and (+/-)-3-(4-hydroxyphenyl)pyrrolidines: selective antagonists at the 1A/2B NMDA receptor subtype.
    Guzikowski AP; Tamiz AP; Acosta-Burruel M; Hong-Bae S; Cai SX; Hawkinson JE; Keana JF; Kesten SR; Shipp CT; Tran M; Whittemore ER; Woodward RM; Wright JL; Zhou ZL
    J Med Chem; 2000 Mar; 43(5):984-94. PubMed ID: 10715162
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of (R)-1-[2-hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol: a novel NR1/2B subtype selective NMDA receptor antagonist.
    Pinard E; Alanine A; Bourson A; Büttelmann B; Gill R; Heitz M; Jaeschke G; Mutel V; Trube G; Wyler R
    Bioorg Med Chem Lett; 2001 Aug; 11(16):2173-6. PubMed ID: 11514163
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Parallel synthesis of a series of subtype-selective NMDA receptor antagonists.
    Gregory TF; Wright JL; Wise LD; Meltzer LT; Serpa KA; Konkoy CS; Whittemore ER; Woodward RM
    Bioorg Med Chem Lett; 2000 Mar; 10(6):527-9. PubMed ID: 10741546
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterisation of striatal NMDA receptors involved in the generation of parkinsonian symptoms: intrastriatal microinjection studies in the 6-OHDA-lesioned rat.
    Nash JE; Brotchie JM
    Mov Disord; 2002 May; 17(3):455-66. PubMed ID: 12112191
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, SAR, and biological evaluation of highly potent benzimidazole-spaced phosphono-alpha-amino acid competitive NMDA antagonists of the AP-6 type.
    Baudy RB; Fletcher H; Yardley JP; Zaleska MM; Bramlett DR; Tasse RP; Kowal DM; Katz AH; Moyer JA; Abou-Gharbia M
    J Med Chem; 2001 May; 44(10):1516-29. PubMed ID: 11334562
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of a series of γ-amino alcohols comprising an N-methyl isoindoline moiety and their evaluation as NMDA receptor antagonists.
    Müller A; Höfner G; Renukappa-Gutke T; Parsons CG; Wanner KT
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5795-9. PubMed ID: 21875803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential interaction of competitive NMDA and AMPA antagonists with selective dopamine D-1 and D-2 agonists in a rat model of Parkinson's disease.
    Löschmann PA; Wüllner U; Heneka MT; Schulz JB; Kunow M; Wachtel H; Klockgether T
    Synapse; 1997 Aug; 26(4):381-91. PubMed ID: 9215597
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antagonism of N-methyl-D-aspartate receptors by sigma site ligands: potency, subtype-selectivity and mechanisms of inhibition.
    Whittemore ER; Ilyin VI; Woodward RM
    J Pharmacol Exp Ther; 1997 Jul; 282(1):326-38. PubMed ID: 9223571
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+parafascicular lesions.
    Truong L; Allbutt HN; Coster MJ; Kassiou M; Henderson JM
    Brain Res Bull; 2009 Feb; 78(2-3):91-6. PubMed ID: 19007866
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differing effects of N-methyl-D-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl-tetrahydropyridine monkeys.
    Blanchet PJ; Konitsiotis S; Whittemore ER; Zhou ZL; Woodward RM; Chase TN
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1034-40. PubMed ID: 10454475
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action.
    Kleckner NW; Glazewski JC; Chen CC; Moscrip TD
    J Pharmacol Exp Ther; 1999 May; 289(2):886-94. PubMed ID: 10215667
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of subtype-selective NMDA receptor ligands: 4-benzyl-1-piperidinylalkynylpyrroles, pyrazoles and imidazoles as NR1A/2B antagonists.
    Wright JL; Gregory TF; Boxer PA; Meltzer LT; Serpa KA; Wise LD
    Bioorg Med Chem Lett; 1999 Oct; 9(19):2815-8. PubMed ID: 10522697
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-activity relationships for a series of bis(phenylalkyl)amines: potent subtype-selective inhibitors of N-methyl-D-aspartate receptors.
    Tamiz AP; Whittemore ER; Zhou ZL; Huang JC; Drewe JA; Chen JC; Cai SX; Weber E; Woodward RM; Keana JF
    J Med Chem; 1998 Aug; 41(18):3499-506. PubMed ID: 9719603
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist.
    Gill R; Alanine A; Bourson A; Buttelmann B; Fischer G; Heitz MP; Kew JN; Levet-Trafit B; Lorez HP; Malherbe P; Miss MT; Mutel V; Pinard E; Roever S; Schmitt M; Trube G; Wybrecht R; Wyler R; Kemp JA
    J Pharmacol Exp Ther; 2002 Sep; 302(3):940-8. PubMed ID: 12183650
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes.
    Pahk AJ; Williams K
    Neurosci Lett; 1997 Mar; 225(1):29-32. PubMed ID: 9143010
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Subtype-selective antagonism of NMDA receptors by nylidrin.
    Whittemore ER; Ilyin VI; Konkoy CS; Woodward RM
    Eur J Pharmacol; 1997 Oct; 337(2-3):197-208. PubMed ID: 9430414
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.